在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human ER degradation-enhancing alpha-mannosidase-like 2 (EDEM2)

Recombinant Human ER degradation-enhancing alpha-mannosidase-like 2 (EDEM2)

  • 中文名稱：
    人EDEM2重組蛋白
  • 貨號：
    CSB-YP861146HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人EDEM2重組蛋白
  • 貨號：
    CSB-EP861146HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人EDEM2重組蛋白
  • 貨號：
    CSB-EP861146HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人EDEM2重組蛋白
  • 貨號：
    CSB-BP861146HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人EDEM2重組蛋白
  • 貨號：
    CSB-MP861146HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    bA4204.1; C20orf31; C20orf49; EDEM 2; EDEM2; EDEM2_HUMAN; ER degradation enhancer mannosidase alpha like 2; ER degradation enhancing alpha mannosidase like 2; ER degradation enhancing alpha mannosidase like protein 2; ER degradation enhancing mannosidase like protein 2; ER degradation-enhancing alpha-mannosidase-like 2; FLJ10783; UNQ573/PRO1135
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    22-578
  • 氨基酸序列
    APGPDGSAP DPAHYRERVK AMFYHAYDSY LENAFPFDEL RPLTCDGHDT WGSFSLTLID ALDTLLILGN VSEFQRVVEV LQDSVDFDID VNASVFETNI RVVGGLLSAH LLSKKAGVEV EAGWPCSGPL LRMAEEAARK LLPAFQTPTG MPYGTVNLLH GVNPGETPVT CTAGIGTFIV EFATLSSLTG DPVFEDVARV ALMRLWESRS DIGLVGNHID VLTGKWVAQD AGIGAGVDSY FEYLVKGAIL LQDKKLMAMF LEYNKAIRNY TRFDDWYLWV QMYKGTVSMP VFQSLEAYWP GLQSLIGDID NAMRTFLNYY TVWKQFGGLP EFYNIPQGYT VEKREGYPLR PELIESAMYL YRATGDPTLL ELGRDAVESI EKISKVECGF ATIKDLRDHK LDNRMESFFL AETVKYLYLL FDPTNFIHNN GSTFDAVITP YGECILGAGG YIFNTEAHPI DPAALHCCQR LKEEQWEVED LMREFYSLKR SRSKFQKNTV SSGPWEPPAR PGTLFSPENH DQARERKPAK QKVPLLSCPS QPFTSKLALL GQVFLDSS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in the endoplasmic reticulum-associated degradation (ERAD) pathway that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. May initiate ERAD by promoting the first mannose trimming step of ERAD substrates, from Man9GlcNAc2 to Man8GlcNAc2. Seems to recognize and bind to exposed hydrophobic regions in target proteins.
  • 基因功能參考文獻：
    1. EDEM2 and OS-9 are required for ER-associated degradation of non-glycosylated sonic hedgehog PMID: 24910992
    2. Glycoproteins mannose trimming from Man9GlcNAc2 to Man8GlcNAc2 is conducted mainly by EDEM2. PMID: 25092655
    3. Overexpression of EDEM2 accelerates the degradation of misfolded alpha1-antitrypsin, indicating that the protein is involved in endoplasmic reticulum associated degradation. PMID: 15537790
    4. EDEM2 regulates endoplasmic reticulum-associated glycoprotein degradation PMID: 15579471
    5. Degrades misfolded alpha1-antitrypsin in the ER. PMID: 15537790

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum lumen.
  • 蛋白家族：
    Glycosyl hydrolase 47 family
  • 組織特異性：
    Expressed ubiquitously in all tissues tested with slightly higher levels detected in small intestine and peripheral blood leukocytes and weakest levels in brain and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 15877

    OMIM: 610302

    KEGG: hsa:55741

    STRING: 9606.ENSP00000363616

    UniGene: Hs.720177



主站蜘蛛池模板： 中字幕久久久人妻熟女天美传媒| 美女张开腿黄网站免费下载| 亚洲日韩欧美一区久久久久我| 国产成人av乱码免费观看| 久久久久蜜桃精品成人片公司 | 国产成人a∨麻豆精品| 好男人社区影院www| 国产精品精华液网站| 一边捏奶头一边啪高潮视频 | 国产欧美一区二区精品久久久| 亚洲va久久久噜噜噜久久狠狠| 蕾丝av无码专区在线观看| 黄床片30分钟免费视频教程| 又大又硬又爽免费视频| 亚洲精品亚洲人成在线| 色天使亚洲综合一区二区| 久久精品超碰av无码| 久久精品国产精品亚洲色婷婷| 色婷婷久久综合中文久久一本| 97色成人综合网站| 草草浮力地址线路①屁屁影院| 丰满人妻熟妇乱又伦精品软件 | 99国产精品久久久久久久久久久| 国产精品无码免费播放| 久久久精品久久日韩一区综合| 麻豆国产成人av在线播放欲色| 亚洲成a人v欧美综合天堂| 亚洲国产精品特色大片观看完整版 | 久久精品国产精品亚洲艾草网 | 超薄丝袜足j好爽在线观看| 女人喷潮完整视频| 国产内射合集颜射| 无码中字出轨中文人妻中文中| 色久悠悠婷婷综合在线亚洲| 免费观看羞羞视频网站| 久久九九精品国产综合喷水| 成人无码a∨电影免费| 国内老熟妇对白xxxxhd| 日本一二免费不卡区| 无码人妻久久一区二区三区app | 精品人妻少妇一区二区三区在线 |