在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Dipeptidyl peptidase 3 (DPP3)

Recombinant Human Dipeptidyl peptidase 3 (DPP3)

  • 中文名稱：
    人DPP3重組蛋白
  • 貨號：
    CSB-YP868352HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人DPP3重組蛋白
  • 貨號：
    CSB-EP868352HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人DPP3重組蛋白
  • 貨號：
    CSB-EP868352HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人DPP3重組蛋白
  • 貨號：
    CSB-BP868352HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人DPP3重組蛋白
  • 貨號：
    CSB-MP868352HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase 3; Dipeptidyl peptidase III; DPP III; dpp3; DPP3_HUMAN; DPPIII; EC 3.4.14.4
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-737
  • 氨基酸序列
    ADTQYILPN DIGVSSLDCR EAFRLLSPTE RLYAYHLSRA AWYGGLAVLL QTSPEAPYIY ALLSRLFRAQ DPDQLRQHAL AEGLTEEEYQ AFLVYAAGVY SNMGNYKSFG DTKFVPNLPK EKLERVILGS EAAQQHPEEV RGLWQTCGEL MFSLEPRLRH LGLGKEGITT YFSGNCTMED AKLAQDFLDS QNLSAYNTRL FKEVDGEGKP YYEVRLASVL GSEPSLDSEV TSKLKSYEFR GSPFQVTRGD YAPILQKVVE QLEKAKAYAA NSHQGQMLAQ YIESFTQGSI EAHKRGSRFW IQDKGPIVES YIGFIESYRD PFGSRGEFEG FVAVVNKAMS AKFERLVASA EQLLKELPWP PTFEKDKFLT PDFTSLDVLT FAGSGIPAGI NIPNYDDLRQ TEGFKNVSLG NVLAVAYATQ REKLTFLEED DKDLYILWKG PSFDVQVGLH ELLGHGSGKL FVQDEKGAFN FDQETVINPE TGEQIQSWYR SGETWDSKFS TIASSYEECR AESVGLYLCL HPQVLEIFGF EGADAEDVIY VNWLNMVRAG LLALEFYTPE AFNWRQAHMQ ARFVILRVLL EAGEGLVTIT PTTGSDGRPD ARVRLDRSKI RSVGKPALER FLRRLQVLKS TGDVAGGRAL YEGYATVTDA PPECFLTLRD TVLLRKESRK LIVQPNTRLE GSDVQLLEYE ASAAGLIRSF SERFPEDGPE LEEILTQLAT ADARFWKGPS EAPSGQA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin. Also cleaves Arg-Arg-beta-naphthylamide (in vitro).
  • 基因功能參考文獻：
    1. We conclude that DPP 3 may influence the cellular expression of Ang-(1-7) and potentially reflect a therapeutic target to augment the actions of the peptide PMID: 27315786
    2. biological function of human dipeptidyl peptidase III PMID: 26887037
    3. several crystal structures of complexes of human dipeptidyl peptidase III with different peptides. PMID: 27025154
    4. Evidence for concurrent expression of hDPP III mRNA V-I and V-II in multiple human tumor derived cell lines. PMID: 27153830
    5. the DPP III conformational landscape and the influence of ligand binding on the protein structure and dynamics, was investigated. PMID: 26334575
    6. Kinetic studies revealed that the single mutant D496G lost selectivity due to the increase of the Km value. The D496G, but not S504G, showed significantly decreased binding of peptides with N-terminal arginine, and of tynorphin. PMID: 25581752
    7. The study used three different conformations of human dipeptidyl-peptidase III (DPP III) to investigate the influence of the protein environment on ligand binding and the Zn(2+) coordination. PMID: 25192149
    8. Deletion/mutagenesis of C/EBP-beta binding motif of DPP III promoter significantly increased its activity and abolished its responsiveness to IL-6 in glioblastoma cells. PMID: 24472318
    9. The activity of the yeast and human dipeptidyl peptidase III were examined. PMID: 23362197
    10. Combined results of mutational analysis and mass spectrometry suggest that glutathionylation (formation of mixed disulfide) of Cys176 and Cys654 contributes to human DPP III inactivation by oxidized glutathione. PMID: 23667907
    11. Amplification and mRNA overexpression of the DPP3 gene is associated with squamous cell lung carcinomas. PMID: 23382044
    12. results provide the basis for the design of specific inhibitors that enable the elucidation of the exact role of DPP III and the exploration of its potential as a target of pain intervention strategies PMID: 22493238
    13. Ets-1/Elk-1 is a critical mediator of DPP3 transcription in human glioblastoma cells. PMID: 20236318
    14. In malignant neoplasms of the ovary DPP III activity increased with growing histologic grade. PMID: 14529681
    15. the conserved tyrosine could be involved in transition state stabilization during the catalytic action of M49 peptidases. PMID: 18163885

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Peptidase M49 family
  • 組織特異性：
    Detected in placenta (at protein level). Detected in erythrocytes (at protein level).
  • 數據庫鏈接：

    HGNC: 3008

    OMIM: 606818

    KEGG: hsa:10072

    STRING: 9606.ENSP00000353701

    UniGene: Hs.502914



主站蜘蛛池模板： 色又黄又爽18禁免费网站现观看| 插一插射一射视频| 久久综合婷婷丁香五月中文字幕| 国产又爽又粗又猛的视频| 亚洲夜夜性无码| 婷婷无套内射影院| 99精品国产福利在线观看| 国产片av片永久免费观看| 亚洲欲色欲色xxxxx在线| 激情人妻另类人妻伦| 亚洲日韩乱码久久久久久| 久久久受www免费人成| 日本孕妇潮喷高潮视频| 亚在线第一国产州精品99| 国产av丝袜一区二区三区| 国产午夜精品一区二区三区四区 | 中文在线天堂а√在线| 免费看欧美成人a片无码| 久久久亚洲精华液精华液精华液 | 欧洲无码一区二区三区在线观看| 午夜性刺激免费看视频| 久在线精品视频线观看| 99久热re在线精品视频| 欧美亚洲日本日韩在线| 亚洲欧美在线观看| 人妻无码一区二区三区 tv| 日产日韩亚洲欧美综合下载| 男人和女人高潮做爰视频| 亚洲国产无套无码av电影| 亚洲国产精品无码久久98| 国产边摸边吃奶边做爽视频| 120秒试看无码体验区| 日韩人妻ol丝袜av一二区| 色窝窝无码一区二区三区色欲| 少妇性俱乐部纵欲狂欢电影| 日本熟妇人妻videos| 久久99精品久久久久蜜芽| 野狼av午夜福利在线| 国产一区二区无码蜜芽精品| 国产一区二区三区不卡在线看| 丰满熟妇被猛烈进入高清片|