在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DPP3 Antibody

  • 中文名稱:
    DPP3兔多克隆抗體
  • 貨號:
    CSB-PA868352ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: DPP3 antibody at 1.39µg/ml + MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 83, 36, 70, 80 kDa
      Observed band size: 83 kDa
    • Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA868352ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA868352ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DPP3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Dipeptidyl aminopeptidase III antibody; Dipeptidyl arylamidase III antibody; Dipeptidyl peptidase 3 antibody; Dipeptidyl peptidase III antibody; DPP III antibody; dpp3 antibody; DPP3_HUMAN antibody; DPPIII antibody; EC 3.4.14.4 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Dipeptidyl peptidase 3 protein (1-280AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin. Also cleaves Arg-Arg-beta-naphthylamide (in vitro).
  • 基因功能參考文獻:
    1. We conclude that DPP 3 may influence the cellular expression of Ang-(1-7) and potentially reflect a therapeutic target to augment the actions of the peptide PMID: 27315786
    2. biological function of human dipeptidyl peptidase III PMID: 26887037
    3. several crystal structures of complexes of human dipeptidyl peptidase III with different peptides. PMID: 27025154
    4. Evidence for concurrent expression of hDPP III mRNA V-I and V-II in multiple human tumor derived cell lines. PMID: 27153830
    5. the DPP III conformational landscape and the influence of ligand binding on the protein structure and dynamics, was investigated. PMID: 26334575
    6. Kinetic studies revealed that the single mutant D496G lost selectivity due to the increase of the Km value. The D496G, but not S504G, showed significantly decreased binding of peptides with N-terminal arginine, and of tynorphin. PMID: 25581752
    7. The study used three different conformations of human dipeptidyl-peptidase III (DPP III) to investigate the influence of the protein environment on ligand binding and the Zn(2+) coordination. PMID: 25192149
    8. Deletion/mutagenesis of C/EBP-beta binding motif of DPP III promoter significantly increased its activity and abolished its responsiveness to IL-6 in glioblastoma cells. PMID: 24472318
    9. The activity of the yeast and human dipeptidyl peptidase III were examined. PMID: 23362197
    10. Combined results of mutational analysis and mass spectrometry suggest that glutathionylation (formation of mixed disulfide) of Cys176 and Cys654 contributes to human DPP III inactivation by oxidized glutathione. PMID: 23667907
    11. Amplification and mRNA overexpression of the DPP3 gene is associated with squamous cell lung carcinomas. PMID: 23382044
    12. results provide the basis for the design of specific inhibitors that enable the elucidation of the exact role of DPP III and the exploration of its potential as a target of pain intervention strategies PMID: 22493238
    13. Ets-1/Elk-1 is a critical mediator of DPP3 transcription in human glioblastoma cells. PMID: 20236318
    14. In malignant neoplasms of the ovary DPP III activity increased with growing histologic grade. PMID: 14529681
    15. the conserved tyrosine could be involved in transition state stabilization during the catalytic action of M49 peptidases. PMID: 18163885

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytosol.
  • 蛋白家族:
    Peptidase M49 family
  • 組織特異性:
    Detected in placenta (at protein level). Detected in erythrocytes (at protein level).
  • 數據庫鏈接:

    HGNC: 3008

    OMIM: 606818

    KEGG: hsa:10072

    STRING: 9606.ENSP00000353701

    UniGene: Hs.502914



主站蜘蛛池模板: 亚洲精品久久中文字幕| 亚洲精品一区二区三区在线| 国产精品自在在线午夜出白浆| 乱子伦一区二区三区| 欧美高清性色生活片免费观看| 国产日韩av无码免费一区二区 | 99久久久无码国产精品6| 东北少妇不戴套对白第一次| 国产一区二区三区四区精华| 一本大道大臿蕉视频无码| a亚洲va欧美va国产综合| 久久精品久久电影免费理论片| 亚洲国产精品久久久天堂麻豆宅男| 日韩av毛片无码免费| 色婷婷亚洲一区二区综合| 国产丝袜美女一区二区三区 | 亚洲国产精品无码久久秋霞| 天堂中文а√在线官网| 亚洲午夜福利av一区二区无码| 人妻少妇被粗大爽.9797pw| 一本色道久久东京热| 无码国产一区二区免费| 高潮毛片又色又爽免费| 高清国产一区二区三区在线| 人成午夜大片免费视频| 日韩a∨精品日韩在线观看| 亚洲自偷自偷图片| 亚洲欧美日韩在线资源观看| 国产亚洲欧洲aⅴ综合一区| 国产成人麻豆亚洲综合无码精品| 国产精品理论片在线观看| 97人洗澡人人澡人人爽人人模| 影音先锋日日狠狠久久| 国产精品青草久久久久福利99| 激情内射亚州一区二区三区爱妻| 一本大道av伊人久久综合 | 国内熟妇人妻色在线视频| 久草热久草热线频97精品| 色一情一乱一伦一区二区三区日本 | 国产亚洲精品无码不卡| 可以免费观看的av毛片下载|