在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Dihydropteridine reductase (QDPR)

  • 中文名稱:
    人QDPR重組蛋白
  • 貨號(hào):
    CSB-YP019133HU
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    人QDPR重組蛋白
  • 貨號(hào):
    CSB-EP019133HU
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    人QDPR重組蛋白
  • 貨號(hào):
    CSB-EP019133HU-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人QDPR重組蛋白
  • 貨號(hào):
    CSB-BP019133HU
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人QDPR重組蛋白
  • 貨號(hào):
    CSB-MP019133HU
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    QDPR
  • Uniprot No.:
  • 別名:
    6,7 dihydropteridine reductase; DHPR; DHPR_HUMAN; Dihydropteridine reductase; HDHPR; HPR; PKU2; Qdpr; Quinoid dihydropteridine reductase; SDR33C1; Short chain dehydrogenase/reductase family 33C, member 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    2-244
  • 氨基酸序列
    AAAAAAGEA RRVLVYGGRG ALGSRCVQAF RARNWWVASV DVVENEEASA SIIVKMTDSF TEQADQVTAE VGKLLGEEKV DAILCVAGGW AGGNAKSKSL FKNCDLMWKQ SIWTSTISSH LATKHLKEGG LLTLAGAKAA LDGTPGMIGY GMAKGAVHQL CQSLAGKNSG MPPGAAAIAV LPVTLDTPMN RKSMPEADFS SWTPLEFLVE TFHDWITGKN RPSSGSLIQV VTTEGRTELT PAYF
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases.
  • 基因功能參考文獻(xiàn):
    1. show for the first time statistically significant up regulation of iNOS in QDPR overexpressing astrocytes. Increased expression of iNOS associated with astrocyte pathology seen in many neurodegenerative disorders may have implications in autoimmune neurodegenerative disorders. PMID: 29355631
    2. Mutation of dihydropteridine reductase (QDPR) inhibited the regulation of TOR serine-threonine kinases (mTOR), suggesting that QDPR is a positive regulator of autophagy via suppressing mTOR signaling. PMID: 28633336
    3. The allele frequencies for the QDPR c.68G > A(0.3%) polymorphism is not a major cause of Parkinson's disease in the Maltese. PMID: 27613114
    4. The mutation spectrum of the QDPR gene is different in the Chinese population. Most mutations are related to severe phenotype. PMID: 25124972
    5. JP1 and JP2 can facilitate the assembly of DHPR with other proteins of the excitation-contraction coupling machinery PMID: 22020936
    6. the electrostatic regulatory interaction between the SPRY2 F loop residues (that bind to imperatoxin A) and the ASI/basic residues of RyR1 does not influence bi-directional DHPR-RyR1 signaling during skeletal EC coupling PMID: 21239886
    7. less than 30 microM H2O2 increase DHPR activities, whereas levels greater than 30 microM H2O2 deactivate the enzyme based on the oxidation of Met146 and Met151 in the sequence, consequently leading to disruption of the NADH-dependent enzyme active site. PMID: 15009710
    8. This protein has been found differentially expressed in the Wernicke's Area from patients with schizophrenia. PMID: 19405953

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Hyperphenylalaninemia, BH4-deficient, C (HPABH4C)
  • 蛋白家族:
    Short-chain dehydrogenases/reductases (SDR) family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 9752

    OMIM: 261630

    KEGG: hsa:5860

    STRING: 9606.ENSP00000281243

    UniGene: Hs.75438



主站蜘蛛池模板: 亚洲免费观看视频| 亚洲精品无码不卡| 中文字幕乱码免费看电影| 日日碰狠狠躁久久躁96avv| 午夜影视啪啪免费体验区入口| 亚洲黑人巨大videos| 天天爽亚洲中文字幕| 天堂va视频一区二区| 色yeye香蕉凹凸视频在线观看| 男女后进式猛烈xx00动态图片 | 久久久久青草线综合超碰| 天码欧美日本一道免费| 日本特黄aaaaaa大片| 无码人妻一区二区三区免费看成人| 日本高清在线一区二区三区| 樱花草在线社区www中国中文 | 精品欧美一区二区在线观看| 中文字幕日本人妻久久久免费| 中文在线а天堂| 免费看女人与公拘交酡过程| 久久精品超碰av无码| 国产三级在线观看完整版| 无码少妇a片一区二区三区| 久久一本久综合久久爱| 俄罗斯少妇性xxxx另类| 国产午夜精品久久久久免费视| 乱女伦露脸对白在线播放| 亚洲精品亚洲人成在线观看| 国产精品青青青在线观看| 欧美激欧美啪啪片| 自拍偷自拍亚洲精品被多人伦好爽 | 成人国产精品一区二区网站公司| 人人超碰人摸人爱| 精品一卡二卡三卡四卡网站 | 无码国产精品一区二区免费16| 初尝黑人嗷嗷叫中文字幕| 国产日韩在线时看高清视频| 中文幕无线码中文字夫妻| 中国精品无码免费专区午夜| 久久99九九精品久久久久蜜桃 | 女人被狂躁c到高潮喷水一区二区|