在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Developmentally-regulated GTP-binding protein 1 (DRG1)

  • 中文名稱:
    人DRG1重組蛋白
  • 貨號:
    CSB-YP897524HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人DRG1重組蛋白
  • 貨號:
    CSB-EP897524HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人DRG1重組蛋白
  • 貨號:
    CSB-EP897524HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人DRG1重組蛋白
  • 貨號:
    CSB-BP897524HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人DRG1重組蛋白
  • 貨號:
    CSB-MP897524HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    DRG1
  • Uniprot No.:
  • 別名:
    Developmentally regulated GTP binding protein 1; Developmentally-regulated GTP-binding protein 1; DKFZp434N1827; DRG 1; DRG-1; DRG1; DRG1_HUMAN; NEDD 3; NEDD-3; NEDD3; Neural precursor cell expressed developmentally down regulated protein 3; Neural precursor cell expressed developmentally down-regulated protein 3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-367
  • 氨基酸序列
    SSTLAKIAE IEAEMARTQK NKATAHHLGL LKARLAKLRR ELITPKGGGG GGPGEGFDVA KTGDARIGFV GFPSVGKSTL LSNLAGVYSE VAAYEFTTLT TVPGVIRYKG AKIQLLDLPG IIEGAKDGKG RGRQVIAVAR TCNLILIVLD VLKPLGHKKI IENELEGFGI RLNSKPPNIG FKKKDKGGIN LTATCPQSEL DAETVKSILA EYKIHNADVT LRSDATADDL IDVVEGNRVY IPCIYVLNKI DQISIEELDI IYKVPHCVPI SAHHRWNFDD LLEKIWDYLK LVRIYTKPKG QLPDYTSPVV LPYSRTTVED FCMKIHKNLI KEFKYALVWG LSVKHNPQKV GKDHTLEDED VIQIVKK
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions.
  • 基因功能參考文獻:
    1. DRG1 was an important protein involved in spindle checkpoint signaling, and elevated levels of DRG1 caused lung adenocarcinoma and taxol resistance. PMID: 27626498
    2. DRG-1 plays an important role in melanoma cell growth and transformation, indicating that DRG1 may represent a novel target for CD4(+) T cell-mediated immunotherapy in melanoma. PMID: 25993655
    3. Lerepo4 action leaves Drg1 affinity for nucleotides unaffected, feasibly favoring a switch I reorientation, mainly via the TGS domain. PMID: 23711155
    4. Drg-1 is a candidate metastasis suppressor gene for prostate cancer and may serve as a useful prognostic marker. PMID: 12702552
    5. our results strongly suggest functional involvement of the Drg-1 gene in suppressing the metastatic advancement of human breast cancer. PMID: 15184886
    6. The tumor metastasis suppressor gene Drg-1 suppresses metastasis of prostate tumor cells by inhibiting the invasive ability of the cells via down-regulation of the expression of the ATF3 gene. PMID: 17178897

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm. Note=The DRG1-ZC3H15/DFRP1 complex associates with polysomes.
  • 蛋白家族:
    TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family
  • 組織特異性:
    High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.
  • 數據庫鏈接:

    HGNC: 3029

    OMIM: 603952

    KEGG: hsa:4733

    STRING: 9606.ENSP00000329715

    UniGene: Hs.115242



主站蜘蛛池模板: 无码熟熟妇丰满人妻porn| 亚洲免费人成视频观看| 日本一区二区三区免费播放视频站| 亚洲成aⅴ人片在线观| 毛片无码国产| 亚洲精品成人无码中文毛片| 国产三级韩国三级日产三级| 国产台湾无码av片在线观看 | 久久丫精品系列| 国产乱来乱子视频| 小雪好紧好滑好湿好爽视频 | 久久婷婷五月综合鬼色| 久久精品一区二区三区中文字幕| 天堂在/线资源中文在线| 欧美性性性性o00xx| 中文字幕久久精品波多野结百度| 18禁成人网站免费观看| 日本成本人片视频免费| 97久久国产成人免费网站| 久久午夜伦鲁片免费无码| 国内精品久久久久伊人av| 色欲视频综合免费天天| www.一区二区三区在线 | 欧洲| 中文字幕精品久久久久人妻红杏1| 欧美日韩精品久久久免费观看| 九色精品国产成人综合网站| 久久99精品国产99久久6不卡 | 亚洲精品乱码久久久久久自慰| 中文字幕乱码中文乱码777| 国模无码人体一区二区| 无人去码一码二码三码区| 一个人看的www片免费高清视频| 国产欧美日韩专区发布| 国产精品亚洲专区无码web| 久久性色欲av免费精品观看| 羞羞影院午夜男女爽爽免费| 欧美刺激性大交| 国产色在线 | 国产| 在线亚洲97se亚洲综合在线| 唐人社导航福利精品| 失禁潮痉挛潮喷av在线无码|