在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Deleted in bladder cancer protein 1 (DBC1)

  • 中文名稱:
    Recombinant Human Deleted in bladder cancer protein 1(DBC1)
  • 貨號:
    CSB-YP006515HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Deleted in bladder cancer protein 1(DBC1)
  • 貨號:
    CSB-EP006515HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Deleted in bladder cancer protein 1(DBC1)
  • 貨號:
    CSB-EP006515HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Deleted in bladder cancer protein 1(DBC1)
  • 貨號:
    CSB-BP006515HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Deleted in bladder cancer protein 1(DBC1)
  • 貨號:
    CSB-MP006515HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    BRINP1
  • Uniprot No.:
  • 別名:
    BMP/retinoic acid-inducible neural-specific protein 1; BRINP1; DBC1; DBC1_HUMAN; DBCCR1 ; Deleted in bladder cancer protein 1; Deleted in bladder cancer protein 1 precursor; FAM5A; IB3089A; Protein FAM5A
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    20-761
  • 氨基酸序列
    V QPSHQEPAGT DQHVSKEFDW LISDRGPFHH SRSYLSFVER HRQGFTTRYK IYREFARWKV RNTAIERRDL VRHPVPLMPE FQRSIRLLGR RPTTQQFIDT IIKKYGTHLL ISATLGGEEA LTMYMDKSRL DRKSGNATQS VEALHQLASS YFVDRDGTMR RLHEIQISTG AIKVTETRTG PLGCNSYDNL DSVSSVLLQS TESKLHLQGL QIIFPQYLQE KFVQSALSYI MCNGEGEYLC QNSQCRCQCA EEFPQCNCPI TDIQIMEYTL ANMAKSWAEA YKDLENSDEF KSFMKRLPSN HFLTIGSIHQ HWGNDWDLQN RYKLLQSATE AQRQKIQRTA RKLFGLSVRC RHNPNHQLPR ERTIQQWLAR VQSLLYCNEN GFWGTFLESQ RSCVCHGSTT LCQRPIPCVI GGNNSCAMCS LANISLCGSC NKGYKLYRGR CEPQNVDSER SEQFISFETD LDFQDLELKY LLQKMDSRLY VHTTFISNEI RLDTFFDPRW RKRMSLTLKS NKNRMDFIHM VIGMSMRICQ MRNSSLDPMF FVYVNPFSGS HSEGWNMPFG EFGYPRWEKI RLQNSQCYNW TLLLGNRWKT FFETVHIYLR SRTRLPTLLR NETGQGPVDL SDPSKRQFYI KISDVQVFGY SLRFNADLLR SAVQQVNQSY TQGGQFYSSS SVMLLLLDIR DRINRLAPPV APGKPQLDLF SCMLKHRLKL TNSEIIRVNH ALDLYNTEIL KQSDQMTAKL C
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.
  • 基因功能參考文獻:
    1. Results found that the expression of DBCCR1 is significantly lower in the lung cancer tissues compared with adjacent non-tumor tissues of patients, and correlates with more advanced stages of cancer, and shorter survival of patients. Interestingly, DBCCR1 attenuates the expression of DNMT1, suggesting a reciprocal regulation between genetic silencing of cancer suppressor genes and activating DNA methylation. PMID: 28427182
    2. we found that the SIRT1 modulators AROS and DBC1 have an impact on hsp70 transcription, HSF1 acetylation status, and HSF1 recruitment to the hsp70 promoter PMID: 23349863
    3. DBC1 modulates the stability and function of the nuclear receptor Rev-erb-alpha. PMID: 23398316
    4. the stress-induced DBC1-SIRT1 interaction is important for cell fate determination following genotoxic stress. PMID: 22465953
    5. Rxpression of DBC1 and SIRT1 is a significant prognostic indicator for breast carcinoma patients. PMID: 21056897
    6. High DBC1 expression is associated with breast and lung cancer.. PMID: 20429629
    7. DBCCR1 is involved in the process of bladder tumorigenesis PMID: 12442002
    8. the prevalent inactivation of DBCCR1 seen at the expression level in astrocytomas is not primarily caused by genomic loss of the gene. PMID: 15643521
    9. likely tumor suppressor for NSCLC;silencing through homozygous deletion or methylation of its promoter promotes progression PMID: 15746151
    10. hypermethylation of the DBC1 promoter region is a frequent event during the development of lymphoproliferative malignancies PMID: 18264085

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    BRINP family
  • 組織特異性:
    Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine.
  • 數據庫鏈接:

    HGNC: 2687

    OMIM: 602865

    KEGG: hsa:1620

    STRING: 9606.ENSP00000265922

    UniGene: Hs.532316



主站蜘蛛池模板: 亚洲啪啪综合av一区| 成人性生交大片免费看| 印度女人狂野牲交| 国产疯狂伦交大片| 一日本道a高清免费播放| 亚洲欧洲免费无码| 久久久久久久女国产乱让韩| 久久熟妇人妻午夜寂寞影院| 亚洲一区二区女搞男| 伊人久久大香线蕉午夜av| 国产av亚洲aⅴ一区二区| 18禁男女无遮挡啪啪网站| 果冻传媒18禁免费视频| 色狠狠av老熟女| 女人的精水喷出来视频| 1000部又爽又黄无遮挡的视频| 奶真大水真多小荡货av| 色舞月亚洲综合一区二区| 国产成人精品高清在线观看93| 任你躁在线精品免费| 免费人成视频x8x8| 久久久久久a亚洲欧洲av| 天天做天天欢摸夜夜摸狠狠摸| 国产精品vr虚拟专区| 亚洲人成色77777在线观看大战p| 亚洲国产精品嫩草影院| 国产成a人亚洲精品无码樱花| 国产精成人品一区| 国产成人无码午夜福利在线直播| 99久久国产露脸精品竹菊传媒 | 爽爽午夜影视窝窝看片| 国产精品免费视频色拍拍| 99在线精品国自产拍| 永久黄网站色视频免费| 中文成人无码精品久久久不卡| 最近中文字幕免费mv在线| 欧美丰满美乳xxⅹ高潮www| 色噜噜av男人的天堂| 国产精品久久久久久久久免费| 欧美怡红院免费全部视频| 九色porny丨国产首页注册|