在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Dedicator of cytokinesis protein 9 (DOCK9), partial

Recombinant Human Dedicator of cytokinesis protein 9 (DOCK9), partial

  • 中文名稱：
    人DOCK9重組蛋白
  • 貨號：
    CSB-YP880144HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人DOCK9重組蛋白
  • 貨號：
    CSB-EP880144HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人DOCK9重組蛋白
  • 貨號：
    CSB-EP880144HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人DOCK9重組蛋白
  • 貨號：
    CSB-BP880144HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人DOCK9重組蛋白
  • 貨號：
    CSB-MP880144HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    DOCK9
  • Uniprot No.：
  • 別名：
    Cdc42 guanine nucleotide exchange factor zizimin 1; Cdc42 guanine nucleotide exchange factor zizimin-1; Dedicator of cytokinesis protein 9; DKFZp686C11110; DKFZp686D2047; DKFZp686N04132; DOCK 9; DOCK9; DOCK9_HUMAN; FLJ16744; FLJ44528; FLJ45282; FLJ45601; KIAA1058; KIAA1085; ZIZ1; Zizimin1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation.
  • 基因功能參考文獻：
    1. c.2262A>C substitution in DOCK9 leads to a splicing aberration. However, because the mutation effect was observed in vitro, a definitive relationship between DOCK9 and KTCN phenotype could not be established. PMID: 26641546
    2. Studies indicate that that many of the mechanistic principles of the exchange process are conserved in the DOCK9-catalyzed reaction. PMID: 19809089
    3. Sequence comparison combined with mutational analysis identified a new domain, which we named CZH2, that mediates direct interaction with Cdc42 PMID: 12172552
    4. DOCK9 contributes to both risk and increased illness severity in bipolar disorder. PMID: 17728666
    5. novel functions for the N-terminal region of zizimin1. PMID: 17935486
    6. DOCK2 and DOCK9 specifically recognize Rac2 and Cdc42 through their switch 1 as well as beta2-beta3 regions and the mode of recognition via switch 1 appears to be conserved among diverse Rac-specific DHR-2 GEFs PMID: 18056264
    7. interaction between Smad2/3 and the Cdc42 guanine nucleotide exchange factor, Zizimin1, in response to TGF-beta1 PMID: 18729074
    8. through structural analysis of DOCK9-Cdc42 complexes, we identify a nucleotide sensor within the alpha10 helix of the DHR2 domain that contributes to release of guanine diphosphate (GDP) and then to discharge of the activated GTP-bound Cdc42 PMID: 19745154

    顯示更多

    收起更多

  • 亞細胞定位：
    Endomembrane system.
  • 蛋白家族：
    DOCK family
  • 組織特異性：
    Widely expressed, with highest expression in heart and placenta. Expressed at intermediate level in kidney, brain, lung and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 14132

    OMIM: 607325

    KEGG: hsa:23348

    STRING: 9606.ENSP00000365643

    UniGene: Hs.596105



主站蜘蛛池模板： 在线日产精品一区| 337p日本欧洲亚洲大胆| 亚洲欧美中文日韩在线v日本 | 在线人人车操人人看视频| 天天狠天天透天干天天| 久久久久亚洲国产av麻豆| 黄网在线观看免费网站| 中文字幕无码日韩专区免费| 2020精品国产视| 久久久精品94久久精品| 丁香激情综合久久伊人久久| 久久久国产精华液| 永久免费无码网站在线观看个| 亚洲综合色无码| 任我撸在线视频| 日韩一区二区三区北条麻妃| 久9视频这里只有精品试看| 亚洲色成人网站www永久| 97久久精品无码一区二区| 国产天美传媒性色av出轨| 亚洲午夜高清国产拍| 国产精品麻豆欧美日韩ww| 国产二级一片内射视频播放| 蜜臀av国产精品久久久久| 国产精品夜色一区二区三区| 国内精品伊人久久久久777| 久久超碰97人人做人人爱| 国产成人麻豆亚洲综合精品| 中文字幕人妻熟女在线| 中文字幕人成乱码熟女香港| 亚洲图片校园另激情类小说| 性欧美大战久久久久久久| 少妇精品无码一区二区三区| 一区二区伊人久久大杳蕉| 国产精品白丝av网站在线观看| 在线看免费无码av天堂| 九九热线精品视频16| 十八禁无码免费网站| 精品国产乱码久久久久久浪潮| 亚洲国产人成自精在线尤物| 国语精品自产拍在线观看网站|