在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Dedicator of cytokinesis protein 9 (DOCK9), partial

Recombinant Human Dedicator of cytokinesis protein 9 (DOCK9), partial

  • 中文名稱：
    人DOCK9重組蛋白
  • 貨號：
    CSB-YP880144HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人DOCK9重組蛋白
  • 貨號：
    CSB-EP880144HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人DOCK9重組蛋白
  • 貨號：
    CSB-EP880144HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人DOCK9重組蛋白
  • 貨號：
    CSB-BP880144HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人DOCK9重組蛋白
  • 貨號：
    CSB-MP880144HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    DOCK9
  • Uniprot No.：
  • 別名：
    Cdc42 guanine nucleotide exchange factor zizimin 1; Cdc42 guanine nucleotide exchange factor zizimin-1; Dedicator of cytokinesis protein 9; DKFZp686C11110; DKFZp686D2047; DKFZp686N04132; DOCK 9; DOCK9; DOCK9_HUMAN; FLJ16744; FLJ44528; FLJ45282; FLJ45601; KIAA1058; KIAA1085; ZIZ1; Zizimin1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation.
  • 基因功能參考文獻：
    1. c.2262A>C substitution in DOCK9 leads to a splicing aberration. However, because the mutation effect was observed in vitro, a definitive relationship between DOCK9 and KTCN phenotype could not be established. PMID: 26641546
    2. Studies indicate that that many of the mechanistic principles of the exchange process are conserved in the DOCK9-catalyzed reaction. PMID: 19809089
    3. Sequence comparison combined with mutational analysis identified a new domain, which we named CZH2, that mediates direct interaction with Cdc42 PMID: 12172552
    4. DOCK9 contributes to both risk and increased illness severity in bipolar disorder. PMID: 17728666
    5. novel functions for the N-terminal region of zizimin1. PMID: 17935486
    6. DOCK2 and DOCK9 specifically recognize Rac2 and Cdc42 through their switch 1 as well as beta2-beta3 regions and the mode of recognition via switch 1 appears to be conserved among diverse Rac-specific DHR-2 GEFs PMID: 18056264
    7. interaction between Smad2/3 and the Cdc42 guanine nucleotide exchange factor, Zizimin1, in response to TGF-beta1 PMID: 18729074
    8. through structural analysis of DOCK9-Cdc42 complexes, we identify a nucleotide sensor within the alpha10 helix of the DHR2 domain that contributes to release of guanine diphosphate (GDP) and then to discharge of the activated GTP-bound Cdc42 PMID: 19745154

    顯示更多

    收起更多

  • 亞細胞定位：
    Endomembrane system.
  • 蛋白家族：
    DOCK family
  • 組織特異性：
    Widely expressed, with highest expression in heart and placenta. Expressed at intermediate level in kidney, brain, lung and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 14132

    OMIM: 607325

    KEGG: hsa:23348

    STRING: 9606.ENSP00000365643

    UniGene: Hs.596105



主站蜘蛛池模板： 久久久无码人妻精品无码| 夜夜高潮夜夜爽夜夜爱| 亂倫近親相姦中文字幕| 国产人妻久久精品二区三区特黄| 国产丝袜在线精品丝袜| 强制高潮18xxxxhd日韩| 日本熟妇人妻xxxx| 国产精品国产三级国产aⅴ下载| 亚洲曰本av在线天堂| 国产成人麻豆亚洲综合精品| 日韩精品人成在线播放| 亚洲熟妇无码一区二区三区导航| 国产精品最新免费视频| 亚洲中文字幕日产无码2020| 熟妇人妻系列av无码一区二区| 国产内射合集颜射| 国产亚洲香蕉线播放αv38| 任我爽橹在线视频精品583| 国产精品51麻豆cm传媒| 免费观看的av在线播放| 天天躁夜夜躁天干天干2020| 开心婷婷五月激情综合社区| 国产精品久久无码一区二区三区网 | 综合亚洲桃色第一影院| 亚洲日韩乱码一区二区三区四区 | 亚洲综合在线视频自拍| 国产精品99爱免费视频| 久在线观看福利视频| 精品噜噜噜噜久久久久久久久| 男女扒开双腿猛进入免费看污| 日韩一区二区三区高清电影| 巨胸美乳无码人妻视频| 久久视频这里只精品99| 丰满岳乱妇久久久| 日本最大色倩网站www| 新版天堂资源中文www连接| 日本一区不卡高清更新二区 | 精品久久久久久亚洲综合网| 蜜臀精品国产高清在线观看| 日韩亚洲国产激情一区浪潮av| 亚洲人av高清无码|