在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DOCK9 Antibody

  • 中文名稱:
    DOCK9兔多克隆抗體
  • 貨號(hào):
    CSB-PA007105GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    DOCK9
  • 別名:
    Cdc42 guanine nucleotide exchange factor zizimin 1 antibody; Cdc42 guanine nucleotide exchange factor zizimin-1 antibody; Dedicator of cytokinesis protein 9 antibody; DKFZp686C11110 antibody; DKFZp686D2047 antibody; DKFZp686N04132 antibody; DOCK 9 antibody; DOCK9 antibody; DOCK9_HUMAN antibody; FLJ16744 antibody; FLJ44528 antibody; FLJ45282 antibody; FLJ45601 antibody; KIAA1058 antibody; KIAA1085 antibody; ZIZ1 antibody; Zizimin1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human DOCK9
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC,IF
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation.
  • 基因功能參考文獻(xiàn):
    1. c.2262A>C substitution in DOCK9 leads to a splicing aberration. However, because the mutation effect was observed in vitro, a definitive relationship between DOCK9 and KTCN phenotype could not be established. PMID: 26641546
    2. Studies indicate that that many of the mechanistic principles of the exchange process are conserved in the DOCK9-catalyzed reaction. PMID: 19809089
    3. Sequence comparison combined with mutational analysis identified a new domain, which we named CZH2, that mediates direct interaction with Cdc42 PMID: 12172552
    4. DOCK9 contributes to both risk and increased illness severity in bipolar disorder. PMID: 17728666
    5. novel functions for the N-terminal region of zizimin1. PMID: 17935486
    6. DOCK2 and DOCK9 specifically recognize Rac2 and Cdc42 through their switch 1 as well as beta2-beta3 regions and the mode of recognition via switch 1 appears to be conserved among diverse Rac-specific DHR-2 GEFs PMID: 18056264
    7. interaction between Smad2/3 and the Cdc42 guanine nucleotide exchange factor, Zizimin1, in response to TGF-beta1 PMID: 18729074
    8. through structural analysis of DOCK9-Cdc42 complexes, we identify a nucleotide sensor within the alpha10 helix of the DHR2 domain that contributes to release of guanine diphosphate (GDP) and then to discharge of the activated GTP-bound Cdc42 PMID: 19745154

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Endomembrane system.
  • 蛋白家族:
    DOCK family
  • 組織特異性:
    Widely expressed, with highest expression in heart and placenta. Expressed at intermediate level in kidney, brain, lung and skeletal muscle.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 14132

    OMIM: 607325

    KEGG: hsa:23348

    STRING: 9606.ENSP00000365643

    UniGene: Hs.596105



主站蜘蛛池模板: 久久婷婷综合激情亚洲狠狠| 日本熟妇乱人伦a片免费高清| 人妻av中文字幕无码专区| 精品无码国产污污污免费网站| 国产内射老熟女aaaa∵| 国产午夜精品免费一区二区三区| 青青草无码精品伊人久久 | 欧美激烈精交gif动态图| 亚洲人成图片小说网站| 啦啦啦www在线观看免费视频| 亚洲久热无码av中文字幕| 国产日产欧产精品| 久久亚洲精品无码av宋| 国产亚洲精品久久yy50| 亚洲欧美一区二区三区日产| 精品国产三级a在线观看| 99久久国产综合精品1| 亚洲国产精品无码观看久久| 国产亚洲精品a在线无码| 亚洲狠狠色成人综合网| 欧美老妇疯狂xxxxbbbb| 精品亚洲成a人在线观看| 中文无码成人免费视频在线观看| 在教室伦流澡到高潮hgl动漫| 亚洲人成网站18禁止大app| 国内a∨免费播放| av大片在线无码永久免费| 丁香五月亚洲中文字幕| 欧美中日韩免费观看网站| 国产精品久久久久久久久久久不卡| 久久精品人妻无码一区二区三区v| 国产成人亚洲精品无码青青草原 | 内射小寡妇无码| 国产偷窥熟女精品视频 | 国产精品毛多多水多| 人人妻人人澡人人爽人人精品av| 性欧美疯狂xxxxbbbb| 国内丰满熟女出轨videos| 伴郎粗大的内捧猛烈进出视频观看| 日本熟妇大乳| 亚洲精品无码久久久久av老牛|