在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DOCK9 Antibody

  • 中文名稱:
    DOCK9兔多克隆抗體
  • 貨號(hào):
    CSB-PA007105GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    DOCK9
  • 別名:
    Cdc42 guanine nucleotide exchange factor zizimin 1 antibody; Cdc42 guanine nucleotide exchange factor zizimin-1 antibody; Dedicator of cytokinesis protein 9 antibody; DKFZp686C11110 antibody; DKFZp686D2047 antibody; DKFZp686N04132 antibody; DOCK 9 antibody; DOCK9 antibody; DOCK9_HUMAN antibody; FLJ16744 antibody; FLJ44528 antibody; FLJ45282 antibody; FLJ45601 antibody; KIAA1058 antibody; KIAA1085 antibody; ZIZ1 antibody; Zizimin1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human DOCK9
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC,IF
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation.
  • 基因功能參考文獻(xiàn):
    1. c.2262A>C substitution in DOCK9 leads to a splicing aberration. However, because the mutation effect was observed in vitro, a definitive relationship between DOCK9 and KTCN phenotype could not be established. PMID: 26641546
    2. Studies indicate that that many of the mechanistic principles of the exchange process are conserved in the DOCK9-catalyzed reaction. PMID: 19809089
    3. Sequence comparison combined with mutational analysis identified a new domain, which we named CZH2, that mediates direct interaction with Cdc42 PMID: 12172552
    4. DOCK9 contributes to both risk and increased illness severity in bipolar disorder. PMID: 17728666
    5. novel functions for the N-terminal region of zizimin1. PMID: 17935486
    6. DOCK2 and DOCK9 specifically recognize Rac2 and Cdc42 through their switch 1 as well as beta2-beta3 regions and the mode of recognition via switch 1 appears to be conserved among diverse Rac-specific DHR-2 GEFs PMID: 18056264
    7. interaction between Smad2/3 and the Cdc42 guanine nucleotide exchange factor, Zizimin1, in response to TGF-beta1 PMID: 18729074
    8. through structural analysis of DOCK9-Cdc42 complexes, we identify a nucleotide sensor within the alpha10 helix of the DHR2 domain that contributes to release of guanine diphosphate (GDP) and then to discharge of the activated GTP-bound Cdc42 PMID: 19745154

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Endomembrane system.
  • 蛋白家族:
    DOCK family
  • 組織特異性:
    Widely expressed, with highest expression in heart and placenta. Expressed at intermediate level in kidney, brain, lung and skeletal muscle.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 14132

    OMIM: 607325

    KEGG: hsa:23348

    STRING: 9606.ENSP00000365643

    UniGene: Hs.596105



主站蜘蛛池模板: 国产精品久久久久久久久久久久 | 日本xxxx色视频在线观看| 120秒试看无码体验区| 国产人妻精品一区二区三首| 亚洲成熟丰满熟妇高潮xxxxx| 国产色婷婷五月精品综合在线| 99久久精品国产成人综合 | 2021久久精品国产99国产精品| 久久精品国产久精国产爱| 国产三级做爰在线播放| 成人亚洲欧美成αⅴ人在线观看| 欧洲免费无线码在线一区| 亚洲成a人片在线观看天堂| 亚洲精品中文字幕| 国产一区二区三区乱码在线观看| 九个美女露脸撒尿嘘嘘视频| 无码中文字幕va精品影院| 少妇人妻大乳在线视频| 丰满少妇被猛烈进入高清播放| 国产亚洲精品久久久久秋霞不卡 | 亚洲精品国产综合久久一线| 色琪琪丁香婷婷综合久久| 免费人成自慰网站| 亚洲精品成人无码中文毛片| 欧美人妻体内射射| 国产精品美女久久久久| 国产av仑乱内谢| 大学生被内谢粉嫩无套| 在线看午夜福利片国产| 轻点好疼好大好爽视频| 7777精品久久久大香线蕉| 欧产日产国产精品| 亚洲午夜无码久久| 免费看男女做爰爽爽视频| 成人av久久一区二区三区| 水蜜桃av导航| 人人妻人人澡人人爽人人dvd| 少妇夜夜春夜夜爽试看视频| 国内精品伊人久久久久网站| 无码夜色一区二区三区| 亚洲精品久久久久高潮|