在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DOCK9 Antibody

  • 中文名稱:
    DOCK9兔多克隆抗體
  • 貨號(hào):
    CSB-PA007105GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    DOCK9
  • 別名:
    Cdc42 guanine nucleotide exchange factor zizimin 1 antibody; Cdc42 guanine nucleotide exchange factor zizimin-1 antibody; Dedicator of cytokinesis protein 9 antibody; DKFZp686C11110 antibody; DKFZp686D2047 antibody; DKFZp686N04132 antibody; DOCK 9 antibody; DOCK9 antibody; DOCK9_HUMAN antibody; FLJ16744 antibody; FLJ44528 antibody; FLJ45282 antibody; FLJ45601 antibody; KIAA1058 antibody; KIAA1085 antibody; ZIZ1 antibody; Zizimin1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human DOCK9
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC,IF
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation.
  • 基因功能參考文獻(xiàn):
    1. c.2262A>C substitution in DOCK9 leads to a splicing aberration. However, because the mutation effect was observed in vitro, a definitive relationship between DOCK9 and KTCN phenotype could not be established. PMID: 26641546
    2. Studies indicate that that many of the mechanistic principles of the exchange process are conserved in the DOCK9-catalyzed reaction. PMID: 19809089
    3. Sequence comparison combined with mutational analysis identified a new domain, which we named CZH2, that mediates direct interaction with Cdc42 PMID: 12172552
    4. DOCK9 contributes to both risk and increased illness severity in bipolar disorder. PMID: 17728666
    5. novel functions for the N-terminal region of zizimin1. PMID: 17935486
    6. DOCK2 and DOCK9 specifically recognize Rac2 and Cdc42 through their switch 1 as well as beta2-beta3 regions and the mode of recognition via switch 1 appears to be conserved among diverse Rac-specific DHR-2 GEFs PMID: 18056264
    7. interaction between Smad2/3 and the Cdc42 guanine nucleotide exchange factor, Zizimin1, in response to TGF-beta1 PMID: 18729074
    8. through structural analysis of DOCK9-Cdc42 complexes, we identify a nucleotide sensor within the alpha10 helix of the DHR2 domain that contributes to release of guanine diphosphate (GDP) and then to discharge of the activated GTP-bound Cdc42 PMID: 19745154

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Endomembrane system.
  • 蛋白家族:
    DOCK family
  • 組織特異性:
    Widely expressed, with highest expression in heart and placenta. Expressed at intermediate level in kidney, brain, lung and skeletal muscle.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 14132

    OMIM: 607325

    KEGG: hsa:23348

    STRING: 9606.ENSP00000365643

    UniGene: Hs.596105



主站蜘蛛池模板: 国产精品国产三级国快看| 麻豆国产原创视频在线播放| 亚洲国产码专区| 免费精品99久久国产综合精品 | 奶头好大狂揉60分钟视频| 国产sm调教折磨视频| 黑人大战中国av女叫惨了| 狠狠噜天天噜日日噜色综合| 精选国产av精选一区二区三区| 成人午夜福利视频镇东影视| 色爱情人网站| 狠狠色狠狠色五月激情| 国产成人青青久久大片| 少妇人妻互换不带套| 国产又色又爽又黄的在线观看视频| 97久久国产成人免费网站| 中文毛片无遮挡高潮免费| 亚洲欧美丝袜精品久久| 日韩欧无码一二三区免费不卡| 日韩在线 | 中文| 欧美成a人片在线观看久| 国产手机在线国内精品| 久久精品国产99久久无毒不卡| 五月丁香综合激情六月久久| 国产成人无码a区在线观看导航| 国产午夜精品一区二区三区极品| 国产亚洲精品久久久久久彩霞| 狠狠噜天天噜日日噜| 国产偷抇久久精品a片69| 午夜福制92视频| 日本熟人妻中文字幕在线| 精品国产精品三级精品av网址| 狠人干练合综合网| 国产高清在线精品一区下载| 精品一区二区三区自拍图片区| 久久久久久av无码免费网站下载| 国产成人啪精品视频网站| 青青草免费国产线观720| 成人aaa片一区国产精品| 久久人人爽人人爽人人片dvd| 久久99er6热线精品首页|