在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human DIS3-like exonuclease 2 (DIS3L2), partial

  • 中文名稱:
    人DIS3L2重組蛋白
  • 貨號(hào):
    CSB-YP818258HU
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    人DIS3L2重組蛋白
  • 貨號(hào):
    CSB-EP818258HU
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    人DIS3L2重組蛋白
  • 貨號(hào):
    CSB-EP818258HU-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人DIS3L2重組蛋白
  • 貨號(hào):
    CSB-BP818258HU
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人DIS3L2重組蛋白
  • 貨號(hào):
    CSB-MP818258HU
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    DIS3L2
  • Uniprot No.:
  • 別名:
    DI3L2_HUMAN; DIS3 L2; DIS3 mitotic control homolog (S. cerevisiae) like 2; DIS3 mitotic control homolog like 2; DIS3-like exonuclease 2; Dis3l2; FLJ36974; MGC42174
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

相關(guān)產(chǎn)品

靶點(diǎn)詳情

  • 功能:
    3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.
  • 基因功能參考文獻(xiàn):
    1. The evidence has been presented that Dis3l2 controls miRNA-9 production. PMID: 27881476
    2. Our findings establish the role of DIS3L2 and oligouridylation as the cytoplasmic quality control for highly structured ncRNAs PMID: 27647875
    3. Studies indicate important roles of the exoribonucleases DIS3L2 and XRN1 in cellular function, viability and disease. PMID: 27911720
    4. these results indicate that catalytically inactive DIS3L2, characteristic of Perlman syndrome, can lead to deregulation of its target RNAs to disturb transcriptome homeostasis. PMID: 27431325
    5. DIS3L2 interacts with Ago2 and governs target RNA-directed miRNA degradation. PMID: 26809675
    6. DIS3L2 is the missing component of the LIN28-TUT4/7-DIS3L2 pathway required for the repression of let-7 in pluripotent cells. PMID: 24141620
    7. in cellular models DIS3L2 knockdown is associated with abnormalities of cell growth and division PMID: 23613427
    8. Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility. PMID: 22306653

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Perlman syndrome (PRLMNS)
  • 亞細(xì)胞定位:
    Cytoplasm. Cytoplasm, P-body.
  • 蛋白家族:
    RNR ribonuclease family, DIS3L2 subfamily
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 28648

    OMIM: 267000

    KEGG: hsa:129563

    STRING: 9606.ENSP00000315569

    UniGene: Hs.732236



主站蜘蛛池模板: 亚洲人成网站色7799| 亚洲精华国产精华精华液网站| 黑人玩弄出轨人妻松雪| 精品国内自产拍在线观看视频| 久久tv中文字幕首页| 国产色视频自在线观看| 久久久水蜜桃国产成人网站| 国产sm精品调教视频网址| 中文字幕制服丝袜第57页| 国产青榴视频在线观看| 亚洲成av人片在线观看无码 | 女人摸下面自熨视频在线播放| 久久精品亚洲精品无码 | 日本黄页网站免费观看| 精品国产一区二区av麻豆不卡 | 久久无码喷吹高潮播放不卡| 日韩免费无码专区精品观看| 国产农村妇女毛片精品久久| 日本大片免a费观看视频三区| 国产亚洲综合区成人国产| 国产99青草视频在线播放视| 国内精品久久久久久影院8f| 亚洲成a v人片在线观看| 玩弄中年熟妇正在播放| 成 人 在 线 免费观看| 草草久久97超级碰碰碰| 免费视频好湿好紧好大好爽| 漂亮人妻被中出中文字幕| 亚洲日韩精品欧美一区二区| 中文字字幕在线中文乱码| 久久久久亚洲精品天堂| 无码免费中文字幕视频| 免费裸体无遮挡黄网站免费看| 亚洲不卡中文字幕无码| 性xxxxx大片免费视频| 他用舌头给我高潮喷水在线 | 无码免费一区二区三区| 久久人搡人人玩人妻精品首页| 亚洲国产精品无码久久青草| 久久热最新网站获取| 国产婷婷色一区二区三区|