在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human DIS3-like exonuclease 2 (DIS3L2), partial

Recombinant Human DIS3-like exonuclease 2 (DIS3L2), partial

  • 中文名稱：
    人DIS3L2重組蛋白
  • 貨號(hào)：
    CSB-YP818258HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    人DIS3L2重組蛋白
  • 貨號(hào)：
    CSB-EP818258HU
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    人DIS3L2重組蛋白
  • 貨號(hào)：
    CSB-EP818258HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人DIS3L2重組蛋白
  • 貨號(hào)：
    CSB-BP818258HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人DIS3L2重組蛋白
  • 貨號(hào)：
    CSB-MP818258HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    DIS3L2
  • Uniprot No.：
  • 別名：
    DI3L2_HUMAN; DIS3 L2; DIS3 mitotic control homolog (S. cerevisiae) like 2; DIS3 mitotic control homolog like 2; DIS3-like exonuclease 2; Dis3l2; FLJ36974; MGC42174
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

相關(guān)產(chǎn)品

靶點(diǎn)詳情

  • 功能：
    3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.
  • 基因功能參考文獻(xiàn)：
    1. The evidence has been presented that Dis3l2 controls miRNA-9 production. PMID: 27881476
    2. Our findings establish the role of DIS3L2 and oligouridylation as the cytoplasmic quality control for highly structured ncRNAs PMID: 27647875
    3. Studies indicate important roles of the exoribonucleases DIS3L2 and XRN1 in cellular function, viability and disease. PMID: 27911720
    4. these results indicate that catalytically inactive DIS3L2, characteristic of Perlman syndrome, can lead to deregulation of its target RNAs to disturb transcriptome homeostasis. PMID: 27431325
    5. DIS3L2 interacts with Ago2 and governs target RNA-directed miRNA degradation. PMID: 26809675
    6. DIS3L2 is the missing component of the LIN28-TUT4/7-DIS3L2 pathway required for the repression of let-7 in pluripotent cells. PMID: 24141620
    7. in cellular models DIS3L2 knockdown is associated with abnormalities of cell growth and division PMID: 23613427
    8. Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility. PMID: 22306653

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Perlman syndrome (PRLMNS)
  • 亞細(xì)胞定位：
    Cytoplasm. Cytoplasm, P-body.
  • 蛋白家族：
    RNR ribonuclease family, DIS3L2 subfamily
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 28648

    OMIM: 267000

    KEGG: hsa:129563

    STRING: 9606.ENSP00000315569

    UniGene: Hs.732236



主站蜘蛛池模板： 免费国产va在线观看| 亚洲欧洲国产成人综合在线观看| 久久99热狠狠色精品一区| 无遮挡又黄又刺激的视频| 亚洲国产成人一区二区在线| 久久99国产精品成人| 亚洲精品无码久久久久yw| 精品成人毛片一区二区| 在线观看国产精品普通话对白精品| 中国丰满人妻videoshd| 最爽无遮挡行房视频| 五月丁香综合缴情六月小说| 骚虎成人免费99xx| 一本加勒比hezyo无码专区| 精精国产xxxx视频在线播放| 精品精品国产男人的天堂| 双腿高潮抽搐喷白浆视频| 中文精品久久久久鬼色| 久久精品国产导航| 区二区三区玖玖玖| 国内精品久久久久久久影视麻豆| 一二三四在线观看视频韩国| 久久人人爽天天玩人人妻精品| 日本在线高清不卡免费播放| 亚洲国产欧美不卡在线观看| 国产激情高中生呻吟视频| 色狠狠av老熟女| 日韩乱码人妻无码系列中文字幕| 亚洲人成网站18禁止大| 国产乱子伦在线一区二区| 精精国产xxxx视频在线| 噜噜色综合噜噜色噜噜色| 亚洲成a×人片在线观看| 中文字幕人妻偷伦在线视频| 欧美真人性做爰全过程| 人人妻人人澡人人爽人人精品浪潮| 强迫大乳人妻中文字幕| 国产未成女一区二区| 播放灌醉水嫩大学生国内精品| 图片区小说区激情区偷拍区 | 精品国产一区av天美传媒|