在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cytosolic beta-glucosidase (GBA3)

  • 中文名稱:
    人GBA3重組蛋白
  • 貨號:
    CSB-YP884446HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人GBA3重組蛋白
  • 貨號:
    CSB-EP884446HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GBA3重組蛋白
  • 貨號:
    CSB-BP884446HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GBA3重組蛋白
  • 貨號:
    CSB-MP884446HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    GBA3
  • Uniprot No.:
  • 別名:
    CBG; CBGL1; Cytosolic beta glucosidase ; Cytosolic beta glucosidase like protein 1; Cytosolic beta-glucosidase; Cytosolic beta-glucosidase-like protein 1; GBA3; GBA3_HUMAN; GLUC; Glucosidase beta acid 3; Klotho related protein ; KLRP
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length of Isoform 2
  • 表達區域:
    1-162
  • 氨基酸序列
    MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides. Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear. Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear. It can also hydrolyze a broad variety of dietary glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens in vitro and could therefore play a role in the metabolism of xenobiotics. Could also play a role in the catabolism of cytosolic sialyl free N-glycans.
  • 基因功能參考文獻:
    1. cytosolic GBA3 is likely involved in the catabolism of cytosolic sialyl free N-glycans, possibly by stabilizing the activity of the NEU2 protein PMID: 26193330
    2. No correlation was observed between GBA3 1368A/T haplotypes and severity of type 1 Gaucher disease manifestation PMID: 20728381
    3. The positioning of a substrate molecule (quercetin-4'-glucoside) by homology modelling revealed that hydrophobic interactions dominate the binding of the aglycone moiety. PMID: 17555766
    4. The crystal structure of a covalent intermediate of the KLrP mutant E165Q, in which glucose was covalently bound to a nucleophile, Glu(373), is reported. PMID: 18662675
  • 亞細胞定位:
    Cytoplasm, cytosol.
  • 蛋白家族:
    Glycosyl hydrolase 1 family, Klotho subfamily
  • 組織特異性:
    Present in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney. Down-regulated in renal cell carcinomas and hepatocellular carcinomas.
  • 數據庫鏈接:

    HGNC: 19069

    OMIM: 606619

    KEGG: hsa:57733

    STRING: 9606.ENSP00000471397

    UniGene: Hs.653107



主站蜘蛛池模板: 99精品国产福利一区二区| 丰满少妇在线观看网站| 婷婷丁香五月亚洲中文字幕| 131美女爱做视频免费| 在线成人精品国产区免费| 美女视频黄是免费| 中文字幕av一区二区三区人妻少妇| 国产精品无码素人福利| 中文字幕在线亚洲二区| 天堂岛国av无码免费无禁网站| 国产成av人片在线观看无码 | 国产亚洲欧美在线专区| 欧美人与动性xxxxx杂| 国产精品成人a区在线观看| 精品少妇人妻av久久久| 日韩人妻无码精品二专区| 欧美日韩亚洲中文字幕一区二区三区 | 印度妓女野外xxww| 和黑人邻居中文字幕在线| 少妇高潮喷水久久久久久久久久| 欧美激情日韩精品久久久| 中国xxxx做受视频| 人人做人人爽久久久精品| 亚洲人成电影综合网站色www| 女人被男人躁得好爽免费视频 | 欧美潮喷少妇100| 国产精品a无线| 人妻教师痴汉电车波多野结衣| 久久av无码aⅴ高潮av喷吹| 女狠狠噜天天噜日日噜| 国产av天堂亚洲国产av麻豆| 欧美人与动性xxxxx杂性| 中文人妻无码一区二区三区信息| 伦理片午夜视频在线观看| 麻豆精品偷拍人妻在线网址 | 成在线人永久免费视频播放| 在线人人车操人人看视频| 国产成人亚洲精品无码车a| 国产做a爰片久久毛片a片| 亚洲中文字幕无码一区二区三区| 女人喷水高潮时的视频网站|