在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cytosolic beta-glucosidase (GBA3)

In Stock
  • 中文名稱:
    人GBA3重組蛋白
  • 貨號:
    CSB-EP884446HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    GBA3
  • Uniprot No.:
  • 別名:
    CBG; CBGL1; Cytosolic beta glucosidase ; Cytosolic beta glucosidase like protein 1; Cytosolic beta-glucosidase; Cytosolic beta-glucosidase-like protein 1; GBA3; GBA3_HUMAN; GLUC; Glucosidase beta acid 3; Klotho related protein ; KLRP
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Isoform 2
  • 來源:
    E.coli
  • 分子量:
    45.3kDa
  • 表達區域:
    1-162aa
  • 氨基酸序列
    MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides. Has a significant glucosylceramidase activity in vitro. However, that activity is relatively low and its significance in vivo is not clear. Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph. However, the in vivo relevance of these activities is unclear. It can also hydrolyze a broad variety of dietary glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens in vitro and could therefore play a role in the metabolism of xenobiotics. Could also play a role in the catabolism of cytosolic sialyl free N-glycans.
  • 基因功能參考文獻:
    1. cytosolic GBA3 is likely involved in the catabolism of cytosolic sialyl free N-glycans, possibly by stabilizing the activity of the NEU2 protein PMID: 26193330
    2. No correlation was observed between GBA3 1368A/T haplotypes and severity of type 1 Gaucher disease manifestation PMID: 20728381
    3. The positioning of a substrate molecule (quercetin-4'-glucoside) by homology modelling revealed that hydrophobic interactions dominate the binding of the aglycone moiety. PMID: 17555766
    4. The crystal structure of a covalent intermediate of the KLrP mutant E165Q, in which glucose was covalently bound to a nucleophile, Glu(373), is reported. PMID: 18662675
  • 亞細胞定位:
    Cytoplasm, cytosol.
  • 蛋白家族:
    Glycosyl hydrolase 1 family, Klotho subfamily
  • 組織特異性:
    Present in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney. Down-regulated in renal cell carcinomas and hepatocellular carcinomas.
  • 數據庫鏈接:

    HGNC: 19069

    OMIM: 606619

    KEGG: hsa:57733

    STRING: 9606.ENSP00000471397

    UniGene: Hs.653107



主站蜘蛛池模板: 国产国产裸模裸模私拍视频| 新版天堂资源中文www连接| 久久精品香蕉绿巨人登场| 成在人线无码aⅴ免费视频| 欧美饥渴熟妇高潮喷水水| 窝窝影院午夜看片| 最新版天堂资源中文官网| 麻豆视传媒官网免费观看| 中文字幕乱偷无码av先锋| 日日躁夜夜躁白天躁晚上| 精品无码欧美黑人又粗又| 亚洲精品一区二区精华液| 亚洲熟妇自偷自拍另类| 欧美国产国产综合视频| 无码写真精品永久福利在线| 欧美日韩视频在线第一区| 女人高潮抽搐喷液30分钟视频| 免费视频欧美无人区码| 亚洲综合熟女久久久40p| 欧美视频网站www色| 亚洲欧美国产精品专区久久| 精品爆乳一区二区三区无码av| 欧美色欧美亚洲日韩在线播放| 久久久久久久综合日本| 国产女人高潮叫床视频| 国产精品色无码av在线观看| 精品精品国产欧美在线小说区| 天天摸天天做天天爽水多| 男女啪祼交视频| 十八禁啪啪无遮挡网站| 国产色秀视频在线播放| 日韩欧美高清dvd碟片| 18禁无遮挡无码网站免费| 韩国国内大量揄拍精品视频| 国产男女猛烈无遮挡免费视频| 欧美牲交a欧美牲交aⅴ免费下载| 精品国产福利在线视频| 中国精学生妹品射精久久| 欧美性插b在线视频网站| 国产精品国产av片国产| 亚洲国产中文在线视频|