在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cytochrome b-c1 complex subunit Rieske, mitochondrial (UQCRFS1)

  • 中文名稱:
    人UQCRFS1重組蛋白
  • 貨號:
    CSB-YP025669HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人UQCRFS1重組蛋白
  • 貨號:
    CSB-EP025669HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人UQCRFS1重組蛋白
  • 貨號:
    CSB-EP025669HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人UQCRFS1重組蛋白
  • 貨號:
    CSB-BP025669HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人UQCRFS1重組蛋白
  • 貨號:
    CSB-MP025669HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Complex III subunit 5; Complex III subunit IX; Cytochrome b c1 complex subunit Rieske mitochondrial; Cytochrome b-c1 complex subunit 11; Cytochrome b-c1 complex subunit 5; Cytochrome b6f complex iron sulfur subunit, chloroplastic; petC; PGR1; Plastohydroquinone:plastocyanin oxidoreductase iron sulfur protein; Proton gradient regulation protein 1; Rieske iron sulfur protein; Rieske iron-sulfur protein; RIP1; RIS1; RISP; Ubiquinol cytochrome C reductase rieske iron sulphur; Ubiquinol cytochrome c reductase Rieske iron-sulfur polypeptide 1; Ubiquinol-cytochrome c reductase 8 kDa protein; Ubiquinol-cytochrome c reductase iron-sulfur subunit; UCRI_HUMAN; UQCR5; UQCRFS1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    79-274
  • 氨基酸序列
    SHTDIKVPDFSEYRRLEVLDSTKSSRESSEARKGFSYLVTGVTTVGVAYAAKNAVTQFVS SMSASADVLALAKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTQKEIEQEAAVELSQLRDP QHDLDRVKKPEWVILIGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRLGPAPLNL EVPTYEFTSDDMVIVG
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. The Rieske protein is a catalytic core subunit containing a Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII). UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer. One of the fragments, called subunit 9, corresponds to its mitochondrial targeting sequence (MTS). The proteolytic processing is necessary for the correct insertion of UQCRFS1 in the complex III dimer, but the persistence of UQCRFS1-derived fragments may prevent newly imported UQCRFS1 to be processed and assembled into complex III and is detrimental for the complex III structure and function.
  • 基因功能參考文獻:
    1. UQCRFS1 produces N-terminal polypeptides, which remain bound to holocomplex III. We show that, in normal conditions, these UQCRFS1 fragments are rapidly removed, but when TTC19 is absent they accumulate within complex III, causing its structural and functional impairment. PMID: 28673544
    2. UQCRFS1/RISP knockdown in breast tumor cell line led to decreased mitochondrial membrane potential as well as a decrease in matrigel invasion. PMID: 21901141
    3. UQCRFS1 gene appears to be involved in development of more aggressive phenotype of breast cancer. PMID: 15047214
  • 亞細胞定位:
    Mitochondrion inner membrane; Single-pass membrane protein.
  • 數據庫鏈接:

    HGNC: 12587

    OMIM: 191327

    KEGG: hsa:7386

    STRING: 9606.ENSP00000306397

    UniGene: Hs.743307



主站蜘蛛池模板: 在线看免费无码av天堂| 亚洲最大成人网 色香蕉| 亚洲成av人片天堂网无码】| 无码精品黑人一区二区三区 | 久久香蕉国产线看观看精品yw| 国产精品女同一区二区| 欧美日韩不卡高清在线看| 亚洲kkk4444在线观看| 欧美 日韩版国产在线播放| 奇米影视7777久久精品| 青娱乐极品视觉盛宴国产视频| 亚洲最新版av无码中文字幕| 欧美成人aa大片| 最新av偷拍av偷窥av网站| 中文字幕精品久久久乱码乱码| 亚洲欧洲无码av不卡在线| 99热成人精品热久久| 亚洲综合国产成人丁香五月激情| 色综合久久久久无码专区| 看国产一毛片在线看手机看| 99精品国产福久久久久久| 国产女主播喷水视频在线观看| 国产精品爽爽久久久久久竹菊| 变态另类先锋影音| 国产无遮挡又黄又爽网站| 久久午夜夜伦鲁鲁片免费无码| 天天综合亚洲色在线精品| 亚洲日韩色在线影院性色| 欧美另类精品xxxx| 青青草国产成人99久久| 青青草国产精品一区二区| 久久国产超碰女女av| 国产精品三级一区二区| 男人扒开女人内裤强吻桶进去| 国产成人亚洲无吗淙合青草| 欧美精品免费观看二区| а天堂中文地址在线| 久久国产福利一区二区| 精品国产午夜福利精品推荐| 好吊色欧美一区二区三区视频 | av无码人妻中文字幕|