在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cysteine-rich motor neuron 1 protein (CRIM1), partial

  • 中文名稱:
    Recombinant Human Cysteine-rich motor neuron 1 protein(CRIM1) ,partial
  • 貨號:
    CSB-YP889163HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Cysteine-rich motor neuron 1 protein(CRIM1) ,partial
  • 貨號:
    CSB-EP889163HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Cysteine-rich motor neuron 1 protein(CRIM1) ,partial
  • 貨號:
    CSB-EP889163HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Cysteine-rich motor neuron 1 protein(CRIM1) ,partial
  • 貨號:
    CSB-BP889163HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Cysteine-rich motor neuron 1 protein(CRIM1) ,partial
  • 貨號:
    CSB-MP889163HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CRIM1
  • Uniprot No.:
  • 別名:
    AU015004; CRIM 1; CRIM-1; CRIM1; CRIM1_HUMAN; Cysteine rich motor neuron 1 protein; Cysteine rich repeat containing protein S52; Cysteine rich transmembrane BMP regulator 1 (chordin like); Cysteine rich transmembrane BMP regulator 1; Cysteine-rich motor neuron protein 1; Cysteine-rich repeat-containing protein S52; MGC138194; Processed cysteine rich motor neuron 1 protein; Processed cysteine-rich motor neuron 1 protein; S52
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface.
  • 基因功能參考文獻:
    1. CRIM1 regulates the expression of several epithelial-mesenchymal transition (EMT) related factors and appears to play a role in suppressing migration and invasion through control of EMT. PMID: 29607933
    2. these findings implicate CRIM1 in endothelial cell development and homeostasis in the coronary vasculature. PMID: 27803996
    3. These observations provide evidence for the first time that CRIM1 plays a role in cancer cells by enhancing the migration and adhesion and increasing the expression of N-CAD and E-CAD. PMID: 26653968
    4. CRIM1 is the causative gene for Colobomatous macrophthalmia with microcornea syndrome and is important for eye development. PMID: 25561690
    5. Knock down of CRIM1 had no effect on VEGF-induced proliferation or migration of umbilical vein endothelial cells (HUVECs), indicating that basal CRIM1 is not involved in the proliferation or migration of endothelial cells. PMID: 25956066
    6. Data suggest that CRIM1 plays role in cancer progression/metastasis, epithelial-mesenchymal transition, and neoplastic angiogenesis. [REVIEW] PMID: 25088037
    7. BMPs inhibitor CRIM1 is increased and correlates with higher levels of serum PIPIII showing an imbalance in favor of pro-fibrotic mechanisms in CHF. PMID: 24617547
    8. CRIM1 is an early response gene in the presence of both angiogenic stimulation (VEGF) and environmental (extracellular matrix) factors, and Erk and FAK might be involved in the upregulation of CRIM1 mRNA expression in vascular endothelial cells. PMID: 25086356
    9. Study demonstrated that CRIM1 is expressed at high levels in resistant leukemia cells, indicating that CRIM1 may play a role in drug-resistance. PMID: 21036735
    10. CRIM1 has a role in capillary formation and maintenance during angiogenesis PMID: 12464430
    11. CRIM1 modulates BMP activity by affecting its processing and delivery to the cell surface PMID: 12805376

    顯示更多

    收起更多

  • 亞細胞定位:
    [Processed cysteine-rich motor neuron 1 protein]: Secreted.; Cell membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Expressed in pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver and small intestine. Expressed in blood vessels (at protein level).
  • 數據庫鏈接:

    HGNC: 2359

    OMIM: 606189

    KEGG: hsa:51232

    STRING: 9606.ENSP00000280527

    UniGene: Hs.699247



主站蜘蛛池模板: 成人精品免费视频在线观看| 天天燥日日燥| 国产真实伦在线观看视频| 精品午夜中文字幕熟女人妻在线| 久久久久久久精品成人热色戒汤唯| 中文国产成人精品久久不卡| 岛国片人妻三上悠亚| 欧美成 人影片 aⅴ免费观看| 亚洲成a∧人片在线播放调教| 香蕉av777xxx色综合一区| 丰满岳乱妇一区二区三区| 亚洲欧美综合一区二区三区| 精品成人免费国产片| 日日摸日日碰夜夜爽无| av免费网站在线观看| 免费特级毛片| 免费看女人与善牲交| 在线亚洲97se亚洲综合在线| 亚洲日韩欧美国产高清αv| 国产精品成人无码久久久| 国产无遮挡乱子伦免费精品| 亚洲日韩亚洲另类| 亚洲字幕av一区二区三区四区| 国产熟女亚洲精品麻豆| 成年日韩片av在线网站| 少妇人妻久久无码专区| 人妻一本久道久久综合久久鬼色| 97久久精品无码一区二区| 玩弄了裸睡少妇人妻野战 | 丝袜足控一区二区三区| 国产乱人伦av麻豆网| 久久香港三级台湾三级播放| 久久综合久久爱久久综合伊人| 国产无套精品一区二区| 又黄又爽吃奶视频在线观看 | 国产成人精品免高潮在线观看| 国产精品自在在线午夜| 亚洲成av人片在www| 日本特黄aaaaaa大片| 亚洲欧美中文日韩v在线观看| 婷婷丁香六月激情综合在线人|