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  4. Recombinant Human Cyclin-dependent kinase 5 activator 2 (CDK5R2), partial

Recombinant Human Cyclin-dependent kinase 5 activator 2 (CDK5R2), partial

  • 中文名稱：
    Recombinant Human Cyclin-dependent kinase 5 activator 2(CDK5R2) ,partial
  • 貨號：
    CSB-YP614404HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Cyclin-dependent kinase 5 activator 2(CDK5R2) ,partial
  • 貨號：
    CSB-EP614404HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Cyclin-dependent kinase 5 activator 2(CDK5R2) ,partial
  • 貨號：
    CSB-EP614404HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Cyclin-dependent kinase 5 activator 2(CDK5R2) ,partial
  • 貨號：
    CSB-BP614404HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Cyclin-dependent kinase 5 activator 2(CDK5R2) ,partial
  • 貨號：
    CSB-MP614404HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CDK5R2
  • Uniprot No.：
  • 別名：
    CD5R2_HUMAN; CDK5 activator 2; Cdk5r2; Cyclin dependent kinase 5 activator 2; Cyclin dependent kinase 5 activator isoform p39i; Cyclin dependent kinase 5 regulatory subunit 2; Cyclin-dependent kinase 5 activator 2; Cyclin-dependent kinase 5 regulatory subunit 2; NCK5AI; Neuronal CDK5 activator isoform; p39; P39I; p39nck5ai
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 表達區域：
    -
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Activator of CDK5/TPKII.
  • 基因功能參考文獻：
    1. p39 is essential for recruiting scaffolding protein muskelin to stress fibers. PMID: 25128817
    2. Hepatocellular carcinoma patients with lower p39 expression had poorer overall survival rate than that with high expression. PMID: 20936377
    3. Our data suggest that neurotoxic insults lead to calpain-mediated conversion of p39 to p29, which might contribute to deregulation of Cdk5 PMID: 11784720
    4. role of the CDK5 molecular complex in the genetic etiology of early-onset Alzheimer disease; a yet unknown functional variant in CDK5 or in a nearby gene might lead to increased susceptibility for early-onset Alzheimer disease PMID: 15917097
  • 亞細胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Cyclin-dependent kinase 5 activator family
  • 組織特異性：
    Brain and neuron specific.
  • 數據庫鏈接：

    HGNC: 1776

    OMIM: 603764

    KEGG: hsa:8941

    STRING: 9606.ENSP00000304250

    UniGene: Hs.158460



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