在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Complement component C9 (C9), partial

Recombinant Human Complement component C9 (C9), partial

  • 中文名稱：
    Recombinant Human Complement component C9(C9),partial
  • 貨號：
    CSB-YP004259HU1
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Complement component C9(C9),partial
  • 貨號：
    CSB-EP004259HU1-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Complement component C9(C9),partial
  • 貨號：
    CSB-BP004259HU1
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Complement component C9(C9),partial
  • 貨號：
    CSB-MP004259HU1
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    C9; Complement component C9
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
  • 基因功能參考文獻：
    1. The data supports the assumption that C9 gene expression may stimulate the expression of inflammatory (NLRP3) and angiogenic growth factors (VEGF) in retinal pigment epithelial cells. PMID: 30090015
    2. Serum-expressed apolipoprotein B-100 protein, C9 Complement, and gelsolin can be used for differential diagnosis of Barrertts esophagus and adenocarcinoma of esophagus. PMID: 26404905
    3. Data indicate that complement C9 binds to the ATPase domain of mortalin. PMID: 24719326
    4. Liver biopsy specimens from chronically hepatitis C virus-infected patients exhibited a lower level of C9 mRNA expression than liver biopsy specimens from unrelated disease or healthy control human liver RNA. PMID: 23487461
    5. the haploinsufficiency of C9, a terminal complement complex component, engenders reduced intraocular secretion of VEGF and decreased risk for CNV development. PMID: 22190594
    6. C9 and fucosylated form could serve as a useful marker for SQLC. PMID: 21840429
    7. It was concluded that variations in the complement component 9 gene are unlikely to influence clearance of chronic hepatitis B virus infection and hepatocellular carcinoma occurrence. PMID: 21380615
    8. Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9. PMID: 21507937
    9. These results suggested that the lack of membrane attack complex because of an Arg95Stop mutation of the complement component 9 gene predisposed patients to pathognomonic glomerulonephritis. PMID: 21057849
    10. provided evidence for the recognition of membrane-bound C9 on complement-lysed ghosts by an antibody specific for the helix-turn-helix fold. PMID: 20153530
    11. Data show that mortalin supports cancer cell resistance to complement-dependent cytotoxicity and suggest consideration of mortalin as a novel target for cancer adjuvant immunotherapy. PMID: 19739077
    12. The human complement C9 gene: structural analysis of the 5' gene region and genetic polymorphism studies. PMID: 11881818
    13. C9 binding is dependent on the N-terminal modules (thrombospondin type 1 and low-density lipoprotein receptor class A) of C8 alpha together with the C8 alpha membrane attack complex/perforin domain. PMID: 12463754
    14. Founder effect was demonstrated for the R95X mutation of the C9 gene in Japanese PMID: 12596049
    15. results indicate that the principal binding site for C9 lies within the MACPF domain of C8alpha PMID: 16618117
    16. analysis of the CD59-C9 binding interaction PMID: 16844690

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Complement component 9 deficiency (C9D); Macular degeneration, age-related, 15 (ARMD15)
  • 亞細胞定位：
    Secreted. Target cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Complement C6/C7/C8/C9 family
  • 組織特異性：
    Plasma (at protein level).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1358

    OMIM: 120940

    KEGG: hsa:735

    STRING: 9606.ENSP00000263408

    UniGene: Hs.654443



主站蜘蛛池模板： 午夜片无码区私人影院| 西西444www大胆无码视频| 久久久一本精品99久久精品66直播| 欧美黑人xxxx性高清版| 国产熟妇按摩3p高潮大叫| 99精品免费久久久久久久久日本| 男女裸体下面进入的免费视频| 亚洲乱码日产精品bd| 亚洲精品久久久久久动漫| 免费久久99精品国产自在现线| 西西444www无码大胆| 色噜噜狠狠色综合网| 精品国产自在现线电影| .精品久久久麻豆国产精品| 亚洲国色天香卡2卡3卡4| 久久久亚洲欧洲日产无码av| 综合亚洲综合图区网友自拍| 男女做爰真人视频直播| 久久国产乱子伦精品免费午夜| 国产成人av大片在线观看| 色妺妺视频网| 亚洲精品一区二区| 欧美日韩国产亚洲沙发| 日本xxxx18野外无毒不卡| 日本精品人妻无码77777| 久在线精品视频线观看| 日本工口里番无遮█彩色| 亚洲va韩国va欧美va| 无码人妻av一二区二区三区| 亚洲精品国产精品制服丝袜| 特级毛片全部免费播放| 免费无码又爽又刺激高潮的视频| 日本丰满熟妇videossex一| 国产主播av福利精品一区| 日本丰满熟妇hd| 激情内射人妻1区2区3区| 麻花豆传媒剧国产免费mv入口| 18禁黄久久久aaa片| 天天天天躁天天爱天天碰2018| 色屁屁www影院免费观看入口| 久久综合色_综合色88|