在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Collectrin (TMEM27), partial

Recombinant Human Collectrin (TMEM27), partial

  • 中文名稱：
    人TMEM27重組蛋白
  • 貨號：
    CSB-YP881018HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人TMEM27重組蛋白
  • 貨號：
    CSB-EP881018HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人TMEM27重組蛋白
  • 貨號：
    CSB-EP881018HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人TMEM27重組蛋白
  • 貨號：
    CSB-BP881018HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人TMEM27重組蛋白
  • 貨號：
    CSB-MP881018HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    TMEM27
  • Uniprot No.：
  • 別名：
    UNQ679; Collectrin; kidney-specific membrane protein; NX-17; NX17; PRO1312; Tmem27; TMM27_HUMAN; Transmembrane protein 27; UNQ679/PRO1312
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their amino acid transporter activity. May also play a role in trafficking of amino acid transporters SLC3A1 and SLC7A9 to the renal cortical cell membrane. Regulator of SNARE complex function. Stimulator of beta cell replication.
  • 基因功能參考文獻：
    1. Maternal serum collectrin levels are significantly lower in patients with preeclampsia than in the control group. There is an inverse correlation between serum collectrin levels and blood pressure. PMID: 28764560
    2. Lack of expression of the TMEM27 in conventional renal cell carcinoma defines a group of patients at high risk for cancer-related death. PMID: 27417314
    3. Tmem27 is present in human serum and its levels are significantly lower in subjects with autoimmune diabetes as compared to healthy individuals. PMID: 24693993
    4. Bace2 specifically targets Tmem27 and cleaves its extracellular domain, which is then shed from the plasma membrane of pancreatic beta cells. PMID: 21907142
    5. Tmem27 dimerization is a dynamic process involving Bace2 PMID: 22628310
    6. Collectrin and ACE2 in renal and intestinal amino acid transport. PMID: 21814048
    7. Data support a role for TMEM27 in glucose-induced insulin secretion but not in cell proliferation. The finding that its cleavage is not specific to beta cells challenges the current support for its use as a potential beta cell mass biomarker. PMID: 20386877
    8. Collectrin has a role in amino acid transpor in the kidney [review] PMID: 17693757
    9. the first human study of the gene TMEM27 and an attempt to shine a light on genotype-phenotype correlation in Turner syndrome patients. PMID: 19417552
    10. No TMEM27 gene mutations were discovered among 26 patients showing a phenotype resembling Dent's disease PMID: 19582483

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    TMEM27 family
  • 組織特異性：
    Kidney; collecting ducts. Pancreas; beta cells of islets.
  • 數據庫鏈接：

    HGNC: 29437

    OMIM: 300631

    KEGG: hsa:57393

    STRING: 9606.ENSP00000369699

    UniGene: Hs.129614



主站蜘蛛池模板： 同性男男黄g片免费网站| 天堂在/线资源中文在线8| 日本无码一区二区三区不卡免费| 日韩欧群交p片内射中文| 亚洲成a人片在线观看你懂的| 亚洲a∨国产av综合av下载 | 99re久久资源最新地址| 午夜免费啪在线观看视频 | 国产美女遭强高潮网站下载| 99久热re在线精品99 6热视频| 老子影院午夜精品无码| 西西444www大胆无码视频| 国语精品自产拍在线观看网站| 国产精品h片在线播放| 好大好湿好硬顶到了好爽视频| 正在播放国产真实哭都没用| 欧美黑人巨大videos极品| 人妻体内射精一区二区三四| 2018国产精华国产精品| 亚洲欧美精品综合在线观看| 少妇人妻无码专区毛片| 乱人伦中文字幕成人网站在线| 十八岁污网站在线观看| 免费看女人与公拘交酡过程| 欧美成人a在线网站| 国产自产v一区二区三区c| 18禁黄无遮挡网站免费| 亚洲精品无码久久久久yw| 欧洲精品卡一卡二卡三| 日韩精品一区二区三区视频| 国产亚洲人成a在线v网站| 国产黄在线观看免费观看不卡| 免费视频爱爱太爽了网站| 欧美三根一起进三p| 狠狠久久噜噜熟女| 免费视频好湿好紧好大好爽| 亚洲愉拍自拍欧美精品| 韩国三级在线观看久| 免费无码av片在线观看网址| 国产亚洲欧美日韩俺去了 | 无码av天天av天天爽|