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  4. Recombinant Human Coenzyme Q-binding protein COQ10 homolog A, mitochondrial (COQ10A)

Recombinant Human Coenzyme Q-binding protein COQ10 homolog A, mitochondrial (COQ10A)

  • 中文名稱：
    Recombinant Human Coenzyme Q-binding protein COQ10 homolog A, mitochondrial(COQ10A)
  • 貨號：
    CSB-YP842716HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Coenzyme Q-binding protein COQ10 homolog A, mitochondrial(COQ10A)
  • 貨號：
    CSB-EP842716HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Coenzyme Q-binding protein COQ10 homolog A, mitochondrial(COQ10A)
  • 貨號：
    CSB-EP842716HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Coenzyme Q-binding protein COQ10 homolog A, mitochondrial(COQ10A)
  • 貨號：
    CSB-BP842716HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Coenzyme Q-binding protein COQ10 homolog A, mitochondrial(COQ10A)
  • 貨號：
    CSB-MP842716HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    COQ10A
  • Uniprot No.：
  • 別名：
    COQ10A; UNQ6192/PRO20219Coenzyme Q-binding protein COQ10 homolog A; mitochondrial
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    16-247
  • 氨基酸序列
    AAERC CRLSLSPGAQ PAPPPGPLPP PRPMRFLTSC SLLLPRAAQI LAAEAGLPSS RSFMGFAAPF TNKRKAYSER RIMGYSMQEM YEVVSNVQEY REFVPWCKKS LVVSSRKGHL KAQLEVGFPP VMERYTSAVS MVKPHMVKAV CTDGKLFNHL ETIWRFSPGI PAYPRTCTVD FSISFEFRSL LHSQLATMFF DEVVKQNVAA FERRAATKFG PETAIPRELM FHEVHQT
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.
  • 基因功能參考文獻：
    1. It is concluded that CoQ10 redox state predicts the concentration of CRP. Persons at risk with lower ubiquinol status, higher BMI, and low grade inflammation may benefit from ubiquinol supplementation PMID: 26910885
    2. In conclusion, urinary CoQ analysis is a noninvasive, reliable, and reproducible method to determine urinary tract CoQ status. PMID: 26768296
    3. Report age-related increase in oxidized proportion of muscle coenzyme Q10. PMID: 26107394
    4. Effect of Coenzyme Q10 on Th1/Th2 Paradigm in Females with Idiopathic Recurrent Pregnancy Loss PMID: 25800618
    5. Serum coenzyme Q10 levels were inversely associated with risk of disabling dementia. PMID: 25463064
    6. When a childhood mitochondrial disorder is suspected, an increased frequency of type 2C fibers in morphologically normal muscle suggests CoQ10 deficiency. PMID: 23494902
    7. coenzyme Q10, superoxide dismutase, and oxidative stress have roles in coronary artery disease, but the effect of malondialdehyde, catalase, and glutathione peroxidase is not significant PMID: 22645453
    8. Rosuvastatin combined with regular exercise preserves coenzyme Q10 levels associated with a significant increase in high-density lipoprotein cholesterol in patients with coronary artery disease PMID: 21458815
    9. plasma coenzyme Q10, asymmetric dimethylarginine and arterial stiffness in patients have a role in phenotypic or genotypic familial hypercholesterolemia with long-term statin therapy PMID: 21640350
    10. Results show no significant differences in paraoxonase, oxLDL, or other oxidative stress markers after 2 months of acetylsalicylic acid treatment. PMID: 19891963

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  • 亞細胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    COQ10 family
  • 數據庫鏈接：

    HGNC: 26515

    KEGG: hsa:93058

    STRING: 9606.ENSP00000312587

    UniGene: Hs.4096



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