在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Clathrin heavy chain 2 (CLTCL1), partial

In Stock
  • 中文名稱:
    Recombinant Human Clathrin heavy chain 2(CLTCL1) ,partial
  • 貨號:
    CSB-EP005594HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    CLTCL1; CLH22; CLTCL; CLTDClathrin heavy chain 2; Clathrin heavy chain on chromosome 22; CLH-22
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    20.8kDa
  • 表達區域:
    1423-1566aa
  • 氨基酸序列
    LLVLSPRLDHTWTVSFFSKAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQGLRASIDAYDNFDNISLAQQLEKHQLMEFRCIAAYLYKGNNWWAQSVELCKKDHLYKDAMQHAAESRDAELAQKLLQWFLEEGKRECF
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
  • 基因功能參考文獻:
    1. Provide biochemical evidence for separate regulation and distinct functional niches for CHC17 and CHC22 in HeLa cells. Furthermore, the greater stability of the CHC22 coat relative to the CHC17 coat may be relevant to its excessive accumulation with GLUT4 during insulin resistance. PMID: 29097553
    2. Clathrin heavy chain 22 contributes to the control of neuropeptide degradation and secretion during neuronal development. Study suggests This suggests that a reduction in CHC22 expression in sensory neural precursors may license a step in neuron precursor neurodevelopment; and that this step is mediated through control of a novel neuropeptide processing pathway. PMID: 29402896
    3. CLTCL1 is significantly upregulated in the developing human brain PMID: 26068709
    4. Depletion of clathrin heavy chain (CHC)17, but not the CHC22 clathrin isoform, by ribonucleic acid interference (RNAi) induces centrosome amplification and multipolar spindles. PMID: 22891263
    5. CHC22 was required for retrograde trafficking of certain cargo molecules from endosomes to the trans-Golgi network. PMID: 20065094
    6. Clathrin isoform CHC22 binds to sorting nexin 5 through a coiled-coil domain. PMID: 15133132
    7. role for CHC22 in formation of insulin-responsive GLUT4 compartments in muscle & adipocytes; CHC22 associated with expanded GLUT4 compartments in muscle in type 2 diabetes PMID: 19478182

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Clathrin heavy chain family
  • 組織特異性:
    Maximal levels in skeletal muscle. High levels in heart and testis. Low expression detected in all other tissues.
  • 數據庫鏈接:

    HGNC: 2093

    OMIM: 601273

    KEGG: hsa:8218

    STRING: 9606.ENSP00000445677

    UniGene: Hs.368266



主站蜘蛛池模板: 国模杨依粉嫩蝴蝶150p| 欧美国产激情一区二区在线| 久久国产精品国产四虎90后| 最新中文乱码字字幕在线| 丰满人妻中伦妇伦精品app| 男女裸交免费无遮挡全过程| 尤物193在线人妻精品免费| 国产亚洲视频在线观看网址 | 精国产品一区二区三区a片| 亚洲 欧美 天堂 综合| 国产精品亚洲二区在线看| 免费无码毛片一区二区三区a片| 国产乱妇无乱码大黄aa片| 国产午夜成人无码免费看不卡| 女高中生自慰污污网站| 久久无码字幕中文久久无码| 免费观看又色又爽又黄的韩国| 又黄又粗又爽免费观看| 无码一区二区三区av在线播放 | 四虎影视88aa久久人妻| 久久久婷婷五月亚洲97色| 熟女性饥渴一区二区三区| 99久久婷婷国产综合精品| 一本久道久久综合久久爱| 和黑人邻居中文字幕在线| 大陆熟妇丰满多毛xxxx| 国产亚洲视频在线观看播放| 亚洲 日韩 国产 有码 不卡| 北条麻妃在线一区二区| 精品熟人妻一区二区三区四区不卡| 亚洲日韩小电影在线观看| 三级网站视频在在线播放| 亚洲午夜国产精品无码老牛影视| 性欧美牲交在线视频| 久久人妻国产精品31| 人人妻人人澡人人爽秒播| 天堂网www在线资源中文| 欧美成人精品 一区二区三区| 亚洲男人第一av网站| 国产sm主人调教女m视频| 久久亚洲色www成人男男|