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  4. Recombinant Human Class A basic helix-loop-helix protein 9 (BHLHA9)

Recombinant Human Class A basic helix-loop-helix protein 9 (BHLHA9)

  • 中文名稱：
    Recombinant Human Class A basic helix-loop-helix protein 9(BHLHA9)
  • 貨號：
    CSB-YP759616HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Class A basic helix-loop-helix protein 9(BHLHA9)
  • 貨號：
    CSB-EP759616HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Class A basic helix-loop-helix protein 9(BHLHA9)
  • 貨號：
    CSB-EP759616HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Class A basic helix-loop-helix protein 9(BHLHA9)
  • 貨號：
    CSB-BP759616HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Class A basic helix-loop-helix protein 9(BHLHA9)
  • 貨號：
    CSB-MP759616HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    BHLHA9
  • Uniprot No.：
  • 別名：
    BHLHA9; BHLHF42Class A basic helix-loop-helix protein 9; bHLHa9; Class F basic helix-loop-helix factor 42; bHLHf42
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-235
  • 氨基酸序列
    MLRGAPGLGL TARKGAEDSA EDLGGPCPEP GGDSGVLGAN GASCSRGEAE EPAGRRRARP VRSKARRMAA NVRERKRILD YNEAFNALRR ALRHDLGGKR LSKIATLRRA IHRIAALSLV LRASPAPRGP CGHLECHGPA ARGDTGDTGA SPPPPAGPSL ARPDAARPSV PSAPRCASCP PHAPLARPSA VAEGPGLAQA SGGSWRRCPG ASSAGPPPWP RGYLRSAPGM GHPRS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcription factor, which play a role in limb development. Is an essential player in the regulatory network governing transcription of genes implicated in limb morphogenesis.
  • 基因功能參考文獻：
    1. Founder triplication of BHLHA9 is associated with femoral-tibial-digital malformations. PMID: 26333411
    2. this is the first study revealing the underlying genetic factor for the development of GWC, and demonstrating the presence of triplications involving BHLHA9 PMID: 25351291
    3. BHLHA9 is identified as an essential player in the regulatory network governing limb morphogenesis in humans. PMID: 25466284
    4. Here, we report on 13 new families presenting with ectrodactyly and harboring a BHLHA9 duplication. PMID: 23790188
    5. BHLHA9 gene contribute to the phenotype of small 17p13.3 chromosomal duplication in Miller-Dieker syndrome PMID: 23035971
    6. Genomic duplications encompassing BHLHA9 are associated with SHFLD and non-Mendelian inheritance characterised by a high degree of non-penetrance with sex bias. PMID: 22147889

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  • 相關疾病：
    Split-hand/foot malformation with long bone deficiency 3 (SHFLD3); Syndactyly, mesoaxial synostotic, with phalangeal reduction (MSSD); Camptosynpolydactyly, complex (CCSPD)
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 數據庫鏈接：

    HGNC: 35126

    OMIM: 607539

    KEGG: hsa:727857

    STRING: 9606.ENSP00000375248

    UniGene: Hs.723790



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