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  4. Recombinant Human Chloride transport protein 6 (CLCN6), partial

Recombinant Human Chloride transport protein 6 (CLCN6), partial

  • 中文名稱：
    Recombinant Human Chloride transport protein 6(CLCN6) ,partial
  • 貨號(hào)：
    CSB-YP005485HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Chloride transport protein 6(CLCN6) ,partial
  • 貨號(hào)：
    CSB-EP005485HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Chloride transport protein 6(CLCN6) ,partial
  • 貨號(hào)：
    CSB-EP005485HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Chloride transport protein 6(CLCN6) ,partial
  • 貨號(hào)：
    CSB-BP005485HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Chloride transport protein 6(CLCN6) ,partial
  • 貨號(hào)：
    CSB-MP005485HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CLCN6
  • Uniprot No.：
  • 別名：
    Chloride channel 6; Chloride channel protein 6; Chloride channel voltage sensitive 6; Chloride transport protein 6; ClC 6; ClC-6; ClC6; CLCN6; CLCN6_HUMAN; KIAA0046
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Chloride transport protein, initially identified as voltage-gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter.
  • 基因功能參考文獻(xiàn)：
    1. These findings implicate the effect of rare coding variants in CLCN6 in Blood Pressure variation and offer new insights into Blood Pressure regulation. PMID: 26658788
    2. A non-synonymous single nucleotide variation (SNV) was identified in the voltage-sensitive chloride channel 6 gene. PMID: 25794116
    3. late endosomal ClC-6 mediates proton/chloride countertransport in heterologous plasma membrane expression PMID: 20466723
    4. differential sorting of endogenous (late endosomal) versus overexpressed (early and recycling endosomal) ClC-6 is reminiscent of that of other late endosomal/lysosomal membrane proteins PMID: 17534424
  • 亞細(xì)胞定位：
    Endosome membrane; Multi-pass membrane protein. Note=Detected in detergent-resistant lipid rafts.
  • 蛋白家族：
    Chloride channel (TC 2.A.49) family, ClC-6/CLCN6 subfamily
  • 組織特異性：
    Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform 3 is only detected in kidney.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 2024

    OMIM: 602726

    KEGG: hsa:1185

    STRING: 9606.ENSP00000234488

    UniGene: Hs.193043



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