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CLCN6 Antibody, FITC conjugated

  • 中文名稱:
    CLCN6兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA005485LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CLCN6 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CLCN6
  • 別名:
    Chloride channel 6 antibody; Chloride channel protein 6 antibody; Chloride channel voltage sensitive 6 antibody; Chloride transport protein 6 antibody; ClC 6 antibody; ClC-6 antibody; ClC6 antibody; CLCN6 antibody; CLCN6_HUMAN antibody; KIAA0046 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Chloride transport protein 6 protein (572-869AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Chloride transport protein, initially identified as voltage-gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter.
  • 基因功能參考文獻:
    1. These findings implicate the effect of rare coding variants in CLCN6 in Blood Pressure variation and offer new insights into Blood Pressure regulation. PMID: 26658788
    2. A non-synonymous single nucleotide variation (SNV) was identified in the voltage-sensitive chloride channel 6 gene. PMID: 25794116
    3. late endosomal ClC-6 mediates proton/chloride countertransport in heterologous plasma membrane expression PMID: 20466723
    4. differential sorting of endogenous (late endosomal) versus overexpressed (early and recycling endosomal) ClC-6 is reminiscent of that of other late endosomal/lysosomal membrane proteins PMID: 17534424
  • 亞細胞定位:
    Endosome membrane; Multi-pass membrane protein. Note=Detected in detergent-resistant lipid rafts.
  • 蛋白家族:
    Chloride channel (TC 2.A.49) family, ClC-6/CLCN6 subfamily
  • 組織特異性:
    Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform 3 is only detected in kidney.
  • 數據庫鏈接:

    HGNC: 2024

    OMIM: 602726

    KEGG: hsa:1185

    STRING: 9606.ENSP00000234488

    UniGene: Hs.193043



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