在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Centrosome-associated protein CEP250 (CEP250), partial

  • 中文名稱:
    Recombinant Human Centrosome-associated protein CEP250(CEP250) ,partial
  • 貨號:
    CSB-YP871581HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Centrosome-associated protein CEP250(CEP250) ,partial
  • 貨號:
    CSB-EP871581HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Centrosome-associated protein CEP250(CEP250) ,partial
  • 貨號:
    CSB-EP871581HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Centrosome-associated protein CEP250(CEP250) ,partial
  • 貨號:
    CSB-BP871581HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Centrosome-associated protein CEP250(CEP250) ,partial
  • 貨號:
    CSB-MP871581HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    CEP250; CEP2; CNAP1Centrosome-associated protein CEP250; 250 kDa centrosomal protein; Cep250; Centrosomal Nek2-associated protein 1; C-Nap1; Centrosomal protein 2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May be involved in ciliogenesis. Probably plays an important role in centrosome cohesion during interphase.
  • 基因功能參考文獻:
    1. C-NAP1-null cells were viable and had an increased frequency of premature centriole separation, accompanied by reduced density of the centriolar satellites, with reexpression of C-NAP1 rescuing both phenotypes. Centrosome amplification induced by DNA damage or by PLK4 or CDK2 overexpression was markedly reduced in the absence of C-NAP1. PMID: 28100636
    2. ASPP1/2 interacted with centrosome linker protein C-Nap1. Co-depletion of ASPP1 and ASPP2 inhibited re-association of C-Nap1 with centrosome at the end of mitosis. PMID: 25660448
    3. multisite phosphorylation precipitates centrosome disjunction at the onset of mitosis PMID: 24695856
    4. A homozygous nonsense CEP250 mutation, in combination with a heterozygous C2orf71 nonsense mutation, causes an atypical form of Usher syndrome, characterised by early-onset sensorineural hearing loss and a relatively mild retinitis pigmentosa. PMID: 24780881
    5. Centlein complexes with C-Nap1 and Cep68 at the proximal ends of centrioles during interphase. PMID: 24554434
    6. C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis. PMID: 23070519
    7. Data show that the dissociation of C-Nap1 from mitotic centrosomes is regulated by localized phosphorylation rather than generalized proteolysis. PMID: 12140259
    8. CEP135 acts as a platform protein for C-NAP1 at the centriole. PMID: 18851962

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment. Note=Component of the core centrosome. In interphase cells, it specifically associates with the proximal ends of both mother and daughter centrioles. Associates with the centrosome in interphase cells. In mitotic cells, it dissociates from the mitotic spindle poles. At the end of cell division, it reaccumulates at centrosomes.
  • 組織特異性:
    Ubiquitously and weakly expressed.
  • 數據庫鏈接:

    HGNC: 1859

    OMIM: 609689

    KEGG: hsa:11190

    STRING: 9606.ENSP00000380661

    UniGene: Hs.443976



主站蜘蛛池模板: 亚洲欧洲精品a片久久99| 亚洲综合色丁香婷婷六月图片| 日韩a无v码在线播放| 一本aⅴ高清一区二区三区| 奇米影视7777久久精品人人爽| 成熟丰满熟妇高潮xxxxx| 都市激情 在线 亚洲 国产| 成年免费视频播放网站推荐| 亚洲中文在线精品国产| 欧美深度肠交惨叫| 美女扒开尿口让男人桶| 2021国产精品国产精华| 国产三级在线观看播放| 性视频播放免费视频| 久久九九久精品国产日韩经典 | 国产偷抇久久精品a片69| 国产做爰xxxⅹ久久久小说| 欧美乱强伦xxxx孕妇| www亚洲精品少妇裸乳一区二区 | 亚洲国产成人久久综合下载| 免费国产精品视频在线| 欧美丰满老妇性猛交| 久久久久人妻精品一区蜜桃| 秋霞av在线露丝片av无码| 天天天天躁天天爱天天碰| 日本饥渴人妻欲求不满| 亚洲精品无人区| 午夜无码精品国产片| 思思久久99热只有频精品66| 色一情一乱一伦一视频免费看| 天堂在线www中文| 国产精品天天看特色大片| 午夜福利视频| 国产成人精品午夜福利在线播放| 人成午夜免费大片| 色窝窝免费一区二区三区| 免费无码一区二区三区a片| 九九久re8在线精品视频| 欧美大屁股熟妇bbbbbb| 久久777国产线看观看精品 | 美女又大又黄www免费网站|