在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CEP250 Antibody, FITC conjugated

CEP250 Antibody, FITC conjugated

  • 中文名稱：
    CEP250兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA871581LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) CEP250 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    CEP250 antibody; CEP2 antibody; CNAP1Centrosome-associated protein CEP250 antibody; 250 kDa centrosomal protein antibody; Cep250 antibody; Centrosomal Nek2-associated protein 1 antibody; C-Nap1 antibody; Centrosomal protein 2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Centrosome-associated protein CEP250 protein (40-293AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May be involved in ciliogenesis. Probably plays an important role in centrosome cohesion during interphase.
  • 基因功能參考文獻(xiàn)：
    1. C-NAP1-null cells were viable and had an increased frequency of premature centriole separation, accompanied by reduced density of the centriolar satellites, with reexpression of C-NAP1 rescuing both phenotypes. Centrosome amplification induced by DNA damage or by PLK4 or CDK2 overexpression was markedly reduced in the absence of C-NAP1. PMID: 28100636
    2. ASPP1/2 interacted with centrosome linker protein C-Nap1. Co-depletion of ASPP1 and ASPP2 inhibited re-association of C-Nap1 with centrosome at the end of mitosis. PMID: 25660448
    3. multisite phosphorylation precipitates centrosome disjunction at the onset of mitosis PMID: 24695856
    4. A homozygous nonsense CEP250 mutation, in combination with a heterozygous C2orf71 nonsense mutation, causes an atypical form of Usher syndrome, characterised by early-onset sensorineural hearing loss and a relatively mild retinitis pigmentosa. PMID: 24780881
    5. Centlein complexes with C-Nap1 and Cep68 at the proximal ends of centrioles during interphase. PMID: 24554434
    6. C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis. PMID: 23070519
    7. Data show that the dissociation of C-Nap1 from mitotic centrosomes is regulated by localized phosphorylation rather than generalized proteolysis. PMID: 12140259
    8. CEP135 acts as a platform protein for C-NAP1 at the centriole. PMID: 18851962

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment. Note=Component of the core centrosome. In interphase cells, it specifically associates with the proximal ends of both mother and daughter centrioles. Associates with the centrosome in interphase cells. In mitotic cells, it dissociates from the mitotic spindle poles. At the end of cell division, it reaccumulates at centrosomes.
  • 組織特異性：
    Ubiquitously and weakly expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1859

    OMIM: 609689

    KEGG: hsa:11190

    STRING: 9606.ENSP00000380661

    UniGene: Hs.443976



主站蜘蛛池模板： 久久精品蜜芽亚洲国产av| 丁香五月亚洲中文字幕| 国产大量精品视频网站| 日本乱偷人妻中文字幕| 午夜射精日本三级| 香蕉欧美成人精品a∨在线观看| 欧美精品亚洲精品日韩专区| 色老头在线一区二区三区| 欧美性生交大片18禁止| 乱码视频午夜间在线观看| 亚洲午夜精品a片一区二区app| 14萝自慰专用网站| 99久久国产宗和精品1上映| 中文无码高潮到痉挛在线视频 | 欧美亚洲日本国产其他| 免费播放婬乱男女婬视频国产| 国产狂喷潮在线观看| 国产产区一二三产区区别在线| 亚洲精品成人老司机影视| 久久只精品99品免费久23| 好吊色欧美一区二区三区视频 | 久久一本久综合久久爱| 99精品全国免费观看视频| av天堂午夜精品一区| 双腿张开被9个男人调教| 国产精品毛片在线完整版| 特黄做受又粗又大又硬老头| 粗了大了 整进去好爽视频| 色8久久人人97超碰香蕉987| 超清制服丝袜无码av福利网| 中文字幕精品一区二区2021年| 国产精品情侣呻吟对白视频| 欧美猛少妇色xxxxx猛交| 亚州久久久久区1区2少妇| 乱中年女人伦| 久久综合给合久久狠狠狠97色69| 日本久久久久久久久久加勒比| 丰满熟妇乱子伦| 国产激情视频一区二区三区| 婷婷久久久亚洲欧洲日产国码av| 少妇人妻大乳在线视频|