在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cathepsin L2 (CTSV)

  • 中文名稱:
    Recombinant Human Cathepsin L2 (CTSV)
  • 貨號:
    CSB-MP006194HUc7
  • 規(guī)格:
    ¥1608
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
  • Uniprot No.:
  • 別名:
    Cathepsin U;Cathepsin V
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    Mammalian cell
  • 分子量:
    36.5 kDa
  • 表達區(qū)域:
    18-334aa
  • 氨基酸序列
    VPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    C-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Cysteine protease. May have an important role in corneal physiology.
  • 基因功能參考文獻:
    1. CTSV is involved in melanosome degradation. PMID: 29654760
    2. exogenous CTSV inhibited Ang -induced hypertrophy in HCM cells by inhibiting PI3K/Akt/mTOR PMID: 28522343
    3. Cathepsins V and S may serve as auxiliary diagnostic and/or prognostic markers in thymic epithelial tumors. PMID: 27771373
    4. E2F1 directly binds to CTSL2 promoter and regulates CTSL2 gene expression. PMID: 23542171
    5. using cathepsin V and cathepsin L as model enzymes, a series of chimeras were generated to identify noncatalytic regions that are responsible for the potent elastolytic activity of cathepsin V PMID: 24121514
    6. Cathepsin V expression contributes to the development of dermal fibrosis and vasculopathy in systemic sclerosis. PMID: 23287360
    7. functions of cathepsin V are controlled by N-glycosylation PMID: 22967898
    8. Findings indicate the unique function of cathepsin V for producing enkephalin and neuropeptide Y (NPY) neuropeptides required for neurotransmission in health and neurological diseases. PMID: 22393040
    9. CTSL2 might be involved in progression of endometrial cancer. PMID: 22452389
    10. A proteolytically active variant of cathepsin V is localized to cell nucleus (in peri-nucleolar pattern) in thyroid carcinoma cells. PMID: 20536394
    11. stratum corneum thiol protease is identical with the recently described cathepsin L2 protease. PMID: 12648222
    12. Cathepsin V is involved in the degradation of invariant chain in human thymus PMID: 12925692
    13. Cathepsin V has an elastolytic activity and is expressed in activated macrophages PMID: 15192101
    14. Human cathepsin V compensates for murine cathepsin L in mouse epidermis and hair follicles. PMID: 15679121
    15. propeptide was found to behave as a tight-binding inhibitor against CatV PMID: 17516850
    16. Associated with type 1 diabetes and early-onset myasthenia gravis. PMID: 17869649
    17. angiogenesis inhibition activity on endothelial cells caused by plasminogen processing by cathepsin V PMID: 18163891

    顯示更多

    收起更多

  • 亞細胞定位:
    Lysosome.
  • 蛋白家族:
    Peptidase C1 family
  • 組織特異性:
    Predominantly expressed in the thymus and testis. Also expressed in corneal epithelium, and to a lesser extent in conjunctival epithelium and skin.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 2538

    OMIM: 603308

    KEGG: hsa:1515

    STRING: 9606.ENSP00000259470

    UniGene: Hs.610096



主站蜘蛛池模板: 88国产精品视频一区二区三区| 理论片午午伦夜理片影院| 亚拍精品一区二区三区探花| 亚洲女人色综合小说| 亚洲精品国产av现线| 人人人妻人人人妻人人人| 成人国产精品一区二区网站公司 | 一本色道久久综合亚州精品蜜桃| 又硬又粗进去好爽免费| 黄瓜视频在线观看网址| 熟女少妇人妻中文字幕| 久久人人爽人人爽人人片| 777米奇影视第四色| 亚洲国产成人最新精品| 亚洲伊人成综合网2222| 两个奶头被吃高潮视频| 久久综合色鬼综合色| 免费看成人午夜福利专区| 国内免费视频成人精品| 香蕉久久精品日日躁夜夜躁夏| 日本中文字幕有码在线视频| 高潮喷水无码av亚洲| 亚洲欧美日韩国产成人一区| 国产亚洲欧洲aⅴ综合一区| 久人人爽人人爽人人片av| 暖暖 免费 高清 日本 在线| 久久人人97超碰超国产| av制服丝袜白丝国产网站| 国产免费无遮挡吸乳视频| 人妻换人妻仑乱| 亚洲精品无码人妻无码| 亚洲日韩精品无码专区加勒比海 | 最新亚洲中文av在线不卡| 九九精品99久久久香蕉| 中文综合在线观| 久久亚洲精品情侣| 牲高潮99爽久久久久777| 精品久久人妻av中文字幕| 国产精品久久久久久妇女| 精品系列无码一区二区三区| av在线无码专区一区|