在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Calmodulin-regulated spectrin-associated protein 2 (CAMSAP2 CAMSAP1L1 KIAA1078)

  • 中文名稱:
  • 貨號:
    CSB-YP004478HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP004478HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP004478HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-BP004478HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-MP004478HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CAMP2
  • Uniprot No.:
  • 別名:
    Calmodulin-regulated spectrin-associated protein 2; Calmodulin-regulated spectrin-associated protein 1-like protein 1; CAMSAP2 CAMSAP1L1 KIAA1078
  • 種屬:
    Homo sapiens (Human)
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus-ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization. Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization. In addition, it also reduces the velocity of microtubule polymerization. Through the microtubule cytoskeleton, also regulates the organization of cellular organelles including the Golgi and the early endosomes. Essential for the tethering, but not for nucleation of non-centrosomal microtubules at the Golgi: together with Golgi-associated proteins AKAP9 and PDE4DIP, required to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Also acts as a regulator of neuronal polarity and development: localizes to non-centrosomal microtubule minus-ends in neurons and stabilizes non-centrosomal microtubules, which is required for neuronal polarity, axon specification and dendritic branch formation. Through the microtubule cytoskeleton, regulates the autophagosome transport.
  • 基因功能參考文獻(xiàn):
    1. The CAMSAP/Nezha/Patronin family protein CAMSAP2 specifically localizes to noncentrosomal microtubule minus-ends and is required for proper microtubule organization in neurons. PMID: 24908486
    2. These results show that members of the CAMSAP/Patronin family all localize to and protect minus-ends but have evolved distinct effects on microtubule dynamics. PMID: 24706919
    3. the rs2292096 G allele of CAMSAP1L1, which was associated with reduced risk of symptomatic epilepsy, tended to associate with increased expression of CAMSAP1L1, which represses neurite outgrowth. PMID: 24148305
    4. in a two-stage GWAS to identify common susceptibility variants of epilepsy in Chinese, the strongest signals were observed with two highly correlated variants, rs2292096 and rs6660197, with the former reaching genome-wide significance, on 1q32.1 in the CAMSAP1L gene PMID: 22116939
    5. The CKK domain binds microtubules and represents a domain that evolved with the metazoa. PMID: 19508979

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Defects in CAMSAP2 may be a cause of susceptibility to epilepsy in the Chinese population.
  • 亞細(xì)胞定位:
    Cytoplasm, cytoskeleton. Golgi apparatus. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm.
  • 蛋白家族:
    CAMSAP1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 29188

    OMIM: 613775

    KEGG: hsa:23271

    UniGene: Hs.23585



主站蜘蛛池模板: 日产精品一区二区| 亚洲一区二区av在线观看| 亚洲a无码综合a国产av中文| 国产成人欧美综合在线影院| 日产精品一区2区卡四卡二卡| 久久无码高潮喷水抽搐| 亚洲国产欧美在线人成aaaa| 国产精品欧美亚洲韩国日本久久| 东北少妇不戴套对白第一次| 日本韩国的免费观看视频| 国产人成无码视频在线1000| 亚洲人成亚洲人成在线观看| 老妇高潮潮喷到猛进猛出| 人妻精品动漫h无码网站| 色综合伊人丁香五月桃花婷婷 | 国产色视频一区二区三区| 亚洲午夜成人久久久久久| 国产美熟女乱又伦av果冻传媒| 日本不卡一区二区三区| 国产精品久久久久久亚洲影视内衣 | 中文字幕被公侵犯的漂亮人妻| 国产剧情国产精品一区| 国产末成年av在线播放| 他掀开裙子把舌头伸进去添视频| 精品熟女日韩中文十区| 法国啄木乌av片在线播放| 黄网站免费永久在线观看下载| 精品久久久久久久中文字幕| 乱码av麻豆丝袜熟女系列| 亚洲日韩精品射精日| 日韩中文字幕在线专区| 成人免费一区二区三区| 巨爆乳无码视频在线观看| 亚洲日韩欧洲无码av夜夜摸| 亚洲国产成人久久综合碰碰| 国产精品三级一区二区| 中文字幕乱码无码人妻系列蜜桃| 国产交换配乱婬视频偷网站| 西西人体大胆午夜视频| www夜片内射视频日韩精品成人| 免费女上男下xx00xx00视频|