在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CAMSAP2 Antibody

  • 中文名稱:
    CAMSAP2兔多克隆抗體
  • 貨號:
    CSB-PA804903ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA804903ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA804903ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CAMSAP2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CAMSAP2
  • 別名:
    CAMSAP2 antibody; CAMSAP1L1 antibody; KIAA1078 antibody; Calmodulin-regulated spectrin-associated protein 2 antibody; Calmodulin-regulated spectrin-associated protein 1-like protein 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Calmodulin-regulated spectrin-associated protein 2 protein (1-150AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus-ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization. Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization. In addition, it also reduces the velocity of microtubule polymerization. Through the microtubule cytoskeleton, also regulates the organization of cellular organelles including the Golgi and the early endosomes. Essential for the tethering, but not for nucleation of non-centrosomal microtubules at the Golgi: together with Golgi-associated proteins AKAP9 and PDE4DIP, required to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Also acts as a regulator of neuronal polarity and development: localizes to non-centrosomal microtubule minus-ends in neurons and stabilizes non-centrosomal microtubules, which is required for neuronal polarity, axon specification and dendritic branch formation. Through the microtubule cytoskeleton, regulates the autophagosome transport.
  • 基因功能參考文獻:
    1. The CAMSAP/Nezha/Patronin family protein CAMSAP2 specifically localizes to noncentrosomal microtubule minus-ends and is required for proper microtubule organization in neurons. PMID: 24908486
    2. These results show that members of the CAMSAP/Patronin family all localize to and protect minus-ends but have evolved distinct effects on microtubule dynamics. PMID: 24706919
    3. the rs2292096 G allele of CAMSAP1L1, which was associated with reduced risk of symptomatic epilepsy, tended to associate with increased expression of CAMSAP1L1, which represses neurite outgrowth. PMID: 24148305
    4. in a two-stage GWAS to identify common susceptibility variants of epilepsy in Chinese, the strongest signals were observed with two highly correlated variants, rs2292096 and rs6660197, with the former reaching genome-wide significance, on 1q32.1 in the CAMSAP1L gene PMID: 22116939
    5. The CKK domain binds microtubules and represents a domain that evolved with the metazoa. PMID: 19508979

    顯示更多

    收起更多

  • 相關疾病:
    Defects in CAMSAP2 may be a cause of susceptibility to epilepsy in the Chinese population.
  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Golgi apparatus. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm.
  • 蛋白家族:
    CAMSAP1 family
  • 數據庫鏈接:

    HGNC: 29188

    OMIM: 613775

    KEGG: hsa:23271

    UniGene: Hs.23585



主站蜘蛛池模板: 国产又色又爽又刺激视频| 欧美又粗又大xxxxbbbb疯狂| 精品影片在线观看的网站| 国产精品无码av天天爽| 国产亚洲精品合集久久久久 | 成人午夜亚洲精品无码区| 亚洲色婷婷久久精品av蜜桃久久| 激情亚洲一区国产精品| 大香伊蕉在人线国产最新75| 伊人久久精品无码av一区| 国产美女精品一区二区三区| 亚洲国产精品一区二区久久| 蜜芽av无码精品国产午夜| 福利姬国产精品一区在线| 又爽又黄又无遮挡的视频| 亚洲国产成人极品综合 | 亚洲国产中文在线视频| 成人无码av片在线观看| 一本久久综合亚洲鲁鲁五月天| 九九九精品成人免费视频| 亚洲欧洲精品成人久久曰影片 | 成人午夜福利院在线观看| aⅴ亚洲 日韩 色 图网站 播放| 亚洲国产精品成人无码区| 天堂资源中文最新版在线一区| 精品无人乱码高清在线观看 | 奇米影视777四色米奇影院| 伊人久久大香线蕉av波多野结衣 | 中文字幕乱码免费看电影| 久久人妻无码aⅴ毛片a片app| 一区二区三区国产精华液| 国产波霸爆乳一区二区| 国产69精品久久久久app下载| 亚洲中文字幕在线精品2021| 99久久人妻精品免费一区| 西西人体做爰大胆gogo| 欧洲无码精品a码无人区| 三级特黄60分钟在线观看| 中文字幕乱码人妻一区二区三区| 成 人 色综合 综合网站| 美国人性欧美xxxx|