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  4. Recombinant Human Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF3), partial

Recombinant Human Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF3), partial

  • 中文名稱：
    Recombinant Human Brefeldin A-inhibited guanine nucleotide-exchange protein 3(ARFGEF3) ,partial
  • 貨號：
    CSB-YP732941HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Brefeldin A-inhibited guanine nucleotide-exchange protein 3(ARFGEF3) ,partial
  • 貨號：
    CSB-EP732941HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Brefeldin A-inhibited guanine nucleotide-exchange protein 3(ARFGEF3) ,partial
  • 貨號：
    CSB-EP732941HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Brefeldin A-inhibited guanine nucleotide-exchange protein 3(ARFGEF3) ,partial
  • 貨號：
    CSB-BP732941HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Brefeldin A-inhibited guanine nucleotide-exchange protein 3(ARFGEF3) ,partial
  • 貨號：
    CSB-MP732941HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ARFGEF3
  • Uniprot No.：
  • 別名：
    ARFGEF3; BIG3; C6orf92; KIAA1244; Brefeldin A-inhibited guanine nucleotide-exchange protein 3; ARFGEF family member 3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Participates in the regulation of systemic glucose homeostasis, where it negatively regulates insulin granule biogenesis in pancreatic islet beta cells. Also regulates glucagon granule production in pancreatic alpha cells. Inhibits nuclear translocation of the transcriptional coregulator PHB2 and may enhance estrogen receptor alpha (ESR1) transcriptional activity in breast cancer cells.
  • 基因功能參考文獻：
    1. BIG3 (ARFGEF3) is predicted to interact with its partner PHB2 through an ARM-type alpha-helical structure. PMID: 24997568
  • 亞細胞定位：
    Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein.
  • 組織特異性：
    Expressed in breast cancer cell lines. Not expressed in normal tissues such as duct, mammary gland, lung, heart, liver, kidnay, bone marrow.
  • 數據庫鏈接：

    HGNC: 21213

    OMIM: 617411

    KEGG: hsa:57221

    UniGene: Hs.194408



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