在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Bone morphogenetic protein 3 (BMP3)

In Stock
  • 中文名稱:
    Recombinant Human Bone morphogenetic protein 3(BMP3)
  • 貨號:
    CSB-EP002739HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    BMP3
  • Uniprot No.:
  • 別名:
    BMP-3; BMP-3A; bmp3; BMP3_HUMAN; BMP3A; Bone morphogenetic protein 3 (osteogenic); Bone morphogenetic protein 3; Bone morphogenetic protein 3A; Osteogenin
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    16.4kDa
  • 表達區域:
    363-472aa
  • 氨基酸序列
    QWIEPRNCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGVVPGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVESCACR
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Initiates signaling cascades by associating with type II receptor ACVR2B to activate SMAD2-dependent and SMAD-independent signaling cascades including TAK1 and JNK pathways.
  • 基因功能參考文獻:
    1. This study demonstrated that there was a significantly higher frequency of BMP3 methylated DNA in plasma in patients with polyps versus healthy controls with a sensitivity and specificity of 40 and 94%, respectively. PMID: 29892846
    2. BMP3 - the biomarker of a currently in-use multi-target stool DNA test was commonly expressed in tumor tissue specimens, independent of Fecal Immunochemical Test result. PMID: 28044229
    3. Methylation level in stool decreases dramatically following colorectal cancer resection PMID: 24993691
    4. Bone morphogenic protein 3 signaling in the regulation of osteogenesis. PMID: 23127436
    5. As an addition to PRKG2 and RASGEFIB genes, we propose to include BMP3 gene as the principal determinant of the observed common phenotype. PMID: 22303795
    6. a critical link between HNF1A-MODY-induced alterations in Bmp-3 expression and insulin gene levels PMID: 21628466
    7. Features supportive of positive selection in the BMP3 gene were found including the presence of an excess of nonsynonymous mutations in modern humans, and a significantly lower genetic diversity that deviates from neutrality PMID: 20532035
    8. Data suggest that promotor region methylation of the BMP3 gene may cause gastric carcinoma in Chinese people. PMID: 20238409
    9. These results demonstrate that BMP-3 stimulates mesenchymal stem cell proliferation via the TGF-beta/activin signaling pathway. PMID: 20143330
    10. The expression signals of BMP3 mRNA in malignant schwannoma were relatively lower than in benign lesions PMID: 11642720
    11. BMP-3 receptor specificity is controlled by the interaction of Lys-30 of BMP-3 with Glu-76 of ActRIIb PMID: 17924656
    12. BMP3 silencing is an early and frequent event in colorectal tumors progressing via the serrated and traditional pathways. PMID: 18311777

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    TGF-beta family
  • 組織特異性:
    Expressed in adult and fetal cartilage.
  • 數據庫鏈接:

    HGNC: 1070

    OMIM: 112263

    KEGG: hsa:651

    STRING: 9606.ENSP00000282701

    UniGene: Hs.387411



主站蜘蛛池模板: 亚洲国产成人高清影视| 波多野结衣中文字幕一区二区三区| 秋霞在线观看秋| 久久婷婷五月综合97色直播| 99久久无码一区人妻a黑 | 亚洲精品伊人久久久大香| 国产极品粉嫩福利姬萌白酱| 国产精品美女久久久久久2018| 欧美国产日韩a在线观看| 亚洲麻豆av成本人无码网站| a毛片终身免费观看网站| 亚洲 丝袜 另类 校园 欧美| 久久99亚洲精品久久99果 | 国产日产亚洲系列最新| 狼色精品人妻在线视频免费| 欧美色欧美亚洲日韩在线播放| 又紧又黄的免费视频网站 | 顶级欧美熟妇高潮xxxxx| 亚洲丰满熟女一区二区v| 欧美疯狂做受xxxxx高潮| 98视频精品全部国产| 亚洲精品国偷自产在线99人热| 久久久久久久97| 人妻另类 专区 欧美 制服| 天干天干夜啦天干天干国产| 蜜臀avwww国产天堂| 久久在线视频免费观看| 人人妻人人澡人人爽国产| 精品一区二区成人精品| 中文精品久久久久人妻不卡| 国产精品无码av天天爽播放器| 欧美熟妇乱子伦xx视频| 被灌满精子的波多野结衣| 日本一本二本三区免费| 亚洲一二三四2021不卡| 亚洲精品少妇高清30p| 免费人成视频在线观看网站| 久久综合亚洲鲁鲁五月天| 亚洲一线产区二线产区分布| 国产乱人伦中文无无码视频试看| 精品熟人妻一区二区三区四区不卡 |