在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

BMP3 Antibody

  • 中文名稱:
    BMP3兔多克隆抗體
  • 貨號:
    CSB-PA001003
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of Jurkat cells using BMP-3 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    BMP3
  • 別名:
    BMP-3 antibody; BMP-3A antibody; bmp3 antibody; BMP3_HUMAN antibody; BMP3A antibody; Bone morphogenetic protein 3 (osteogenic) antibody; Bone morphogenetic protein 3 antibody; Bone morphogenetic protein 3A antibody; Osteogenin antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human BMP-3.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Initiates signaling cascades by associating with type II receptor ACVR2B to activate SMAD2-dependent and SMAD-independent signaling cascades including TAK1 and JNK pathways.
  • 基因功能參考文獻:
    1. This study demonstrated that there was a significantly higher frequency of BMP3 methylated DNA in plasma in patients with polyps versus healthy controls with a sensitivity and specificity of 40 and 94%, respectively. PMID: 29892846
    2. BMP3 - the biomarker of a currently in-use multi-target stool DNA test was commonly expressed in tumor tissue specimens, independent of Fecal Immunochemical Test result. PMID: 28044229
    3. Methylation level in stool decreases dramatically following colorectal cancer resection PMID: 24993691
    4. Bone morphogenic protein 3 signaling in the regulation of osteogenesis. PMID: 23127436
    5. As an addition to PRKG2 and RASGEFIB genes, we propose to include BMP3 gene as the principal determinant of the observed common phenotype. PMID: 22303795
    6. a critical link between HNF1A-MODY-induced alterations in Bmp-3 expression and insulin gene levels PMID: 21628466
    7. Features supportive of positive selection in the BMP3 gene were found including the presence of an excess of nonsynonymous mutations in modern humans, and a significantly lower genetic diversity that deviates from neutrality PMID: 20532035
    8. Data suggest that promotor region methylation of the BMP3 gene may cause gastric carcinoma in Chinese people. PMID: 20238409
    9. These results demonstrate that BMP-3 stimulates mesenchymal stem cell proliferation via the TGF-beta/activin signaling pathway. PMID: 20143330
    10. The expression signals of BMP3 mRNA in malignant schwannoma were relatively lower than in benign lesions PMID: 11642720
    11. BMP-3 receptor specificity is controlled by the interaction of Lys-30 of BMP-3 with Glu-76 of ActRIIb PMID: 17924656
    12. BMP3 silencing is an early and frequent event in colorectal tumors progressing via the serrated and traditional pathways. PMID: 18311777

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    TGF-beta family
  • 組織特異性:
    Expressed in adult and fetal cartilage.
  • 數據庫鏈接:

    HGNC: 1070

    OMIM: 112263

    KEGG: hsa:651

    STRING: 9606.ENSP00000282701

    UniGene: Hs.387411



主站蜘蛛池模板: 国产精品白丝喷浆| 成人内射国产免费观看| 五月丁香六月综合av| 亚洲男女羞羞无遮挡久久丫| 激情综合亚洲色婷婷五月| 国内精品久久久久久影院8f| 极品人妻videosss人妻| 18禁免费观看网站| 欧洲美洲精品一区二区三区| 成人免费无码不卡毛片视频| 精品女同一区二区| 精品人妻伦一二三区久久| 国产亚洲精品第一综合不卡| 国产成人无码激情视频| 日日碰狠狠添天天爽无码| 无码中文av有码中文av| 国产精品边做奶水狂喷无码| 亚洲国产成人无码电影| 国产免费艾彩sm调教视频| 四虎影视国产精品久久| 玩弄少妇的肉体k8经典| 日本日本乱码伦专区| 一区二区三区在线 | 欧洲| 亚洲精品国产精品乱码不99| 日本一道本高清一区二区| 中文字幕无码日韩中文字幕| 国产精品区免费视频| 九色九九九老阿姨| 国产无遮挡又爽又黄大胸免费| 337p日本欧洲亚洲大胆精筑| 久久久久九九精品影院| 日本老妇人乱xxy| 亚洲乱码卡一卡二卡| 久久97超碰色中文字幕总站| 精品人妻av一区二区三区| 国产偷伦视频片免费视频| 亚洲午夜成人精品无码| 日韩av午夜在线观看| 久久综合给合久久狠狠狠97色69| 狠狠躁夜夜躁人人爽天天bl| 亚洲成a人v欧美综合天堂|