在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2)

Recombinant Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2)

  • 中文名稱：
    人PAPSS2重組蛋白
  • 貨號：
    CSB-YP527262HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PAPSS2重組蛋白
  • 貨號：
    CSB-EP527262HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PAPSS2重組蛋白
  • 貨號：
    CSB-EP527262HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PAPSS2重組蛋白
  • 貨號：
    CSB-BP527262HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PAPSS2重組蛋白
  • 貨號：
    CSB-MP527262HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PAPSS2
  • Uniprot No.：
  • 別名：
    PAPSS2; ATPSK2Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2; PAPS synthase 2; PAPSS 2; Sulfurylase kinase 2; SK 2; SK2) [Includes: Sulfate adenylyltransferase; EC 2.7.7.4; ATP-sulfurylase; Sulfate adenylate transferase; SAT); Adenylyl-sulfate kinase; EC 2.7.1.25; 3'-phosphoadenosine-5'-phosphosulfate synthase; APS kinase; Adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenylylsulfate 3'-phosphotransferase)]
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-614
  • 氨基酸序列
    MSGIKKQKTE NQQKSTNVVY QAHHVSRNKR GQVVGTRGGF RGCTVWLTGL SGAGKTTISF ALEEYLVSHA IPCYSLDGDN VRHGLNRNLG FSPGDREENI RRIAEVAKLF ADAGLVCITS FISPFAKDRE NARKIHESAG LPFFEIFVDA PLNICESRDV KGLYKRARAG EIKGFTGIDS DYEKPETPER VLKTNLSTVS DCVHQVVELL QEQNIVPYTI IKDIHELFVP ENKLDHVRAE AETLPSLSIT KLDLQWVQVL SEGWATPLKG FMREKEYLQV MHFDTLLDDG VINMSIPIVL PVSAEDKTRL EGCSKFVLAH GGRRVAILRD AEFYEHRKEE RCSRVWGTTC TKHPHIKMVM ESGDWLVGGD LQVLEKIRWN DGLDQYRLTP LELKQKCKEM NADAVFAFQL RNPVHNGHAL LMQDTRRRLL ERGYKHPVLL LHPLGGWTKD DDVPLDWRMK QHAAVLEEGV LDPKSTIVAI FPSPMLYAGP TEVQWHCRSR MIAGANFYIV GRDPAGMPHP ETKKDLYEPT HGGKVLSMAP GLTSVEIIPF RVAAYNKAKK AMDFYDPARH NEFDFISGTR MRKLAREGEN PPDGFMAPKA WKVLTDYYRS LEKN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate/PAPS, the activated sulfate donor used by sulfotransferases. In mammals, PAPS is the sole source of sulfate while APS appears to only be an intermediate in the sulfate-activation pathway. Plays indirectly an important role in skeletogenesis during postnatal growth.
  • 基因功能參考文獻：
    1. In an Amish population, using expression profiling of genes within regions identified by a meta-analysis GWAS of survival to age 90, we localized PAPSS2 as a candidate gene for extended life span. These results provide novel evidence for genetic loci implicated in longevity and incorporate gene expression results from a unique population to locate positional candidates. PMID: 26896383
    2. Silencing of SULT1A1 and PAPSS2 led to a significant decrease in aristolactam-DNA levels in both cell lines following exposure to AA-I, indicating the critical role for sulfonation in the activation of AA-I in vivo Since HK-2 cells proved relatively resistant to knockdown with siRNAs PMID: 27207664
    3. Our results indicate that FGFR2 and PAPSS2 may play an important role in the regulation of magnesium homeostasis in children of European-American ancestry. PMID: 26685716
    4. Results suggest that the loss of the susceptible region on chromosome 10q, which implicates PTEN, FAS and PAPSS2 may serve as genetic predictors of PSA recurrence after radical prostatectomy. PMID: 25679447
    5. Direct in vivo evidence for the significant functional impact of mutant PAPSS2 on DHEA sulfation and androgen activation. PMID: 25594860
    6. PAPSS2-brachyolmia includes phenotypes of the conventional clinical concept of brachyolmia, the Hobaek and Toledo types, and is associated with abnormal androgen metabolism. PMID: 23824674
    7. Papss2 expression is reduced in articular cartilage following transforming growth factor-beta administration. PMID: 22394585
    8. PAPSS2 is the disease gene for an autosomal recessive brachyolmia. PMID: 22791835
    9. Unusual localisation signals of both PAPS synthase isoforms, are described. PMID: 22242175
    10. Thirty-seven novel SNPs in the PAPSS2 gene and in two intergenic regions on chromosomes 2q33.1 and 18p11.32 were associated with exercise participation. PMID: 19727025
    11. Transcriptional regulation of human 3'-phosphoadenosine 5'-phosphosulphate synthase 2. PMID: 11931653

    顯示更多

    收起更多

  • 相關疾病：
    Brachyolmia type 4 with mild epiphyseal and metaphyseal changes (BCYM4)
  • 蛋白家族：
    APS kinase family; Sulfate adenylyltransferase family
  • 組織特異性：
    Expressed in cartilage and adrenal gland.
  • 數據庫鏈接：

    HGNC: 8604

    OMIM: 603005

    KEGG: hsa:9060

    STRING: 9606.ENSP00000406157

    UniGene: Hs.524491



主站蜘蛛池模板： 欧美日韩在线视频| 2020精品国产户外| 亚洲人成网站色www| 99这里只有精品| 亚洲综合小说专区图片| 国内精品久久久久影院优| 亚洲人成人网站在线观看| 97在线视频人妻无码| 亚洲国产一区二区三区在观看| 日本高清www无色夜在线视频| 日韩欧群交p片内射中文| 久久99精品久久久久久动态图| 中文字幕熟妇人妻在线视频| 免费无码成人av在线播放不卡| 无码熟妇人妻av在线电影| 丰满熟妇人妻中文字幕| 中文字幕v亚洲日本在线| 国产在线精品一品二区| 中文字幕无码乱人伦| 亚洲精品一区二区三区在线观看| 日日摸天天摸人人看| 日日摸日日碰夜夜爽亚洲 | 欧美又大粗又爽又黄大片视频| 亚洲综合av色婷婷| 亚洲麻豆av成本人无码网站| 国产裸体舞一区二区三区| 国产精品久久久久7777| 亚洲欧美偷国产日韩| 亚州中文字幕午夜福利电影| 无码人妻精一区二区三区| 欧美亚洲偷图色综合| 乱码精品一区二区三区 | 真人与拘做受免费视频| 风韵犹存丰满大屁股熟妇| 精品国产乱码久久久软件下载| 亚洲欧洲中文日韩久久av乱码| 久久国产精品一国产精品| 亚洲中文字幕在线精品2021| 免费无码又爽又黄又刺激网站| 两个人看的www在线观看| 亚洲综合精品第一页|