在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PAPSS2 Antibody

PAPSS2 Antibody

  • 中文名稱：
    PAPSS2兔多克隆抗體
  • 貨號：
    CSB-PA527262LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of MCF-7 cells with CSB-PA527262LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PAPSS2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PAPSS2
  • 別名：
    PAPSS2 antibody; ATPSK2Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 antibody; PAPS synthase 2 antibody; PAPSS 2 antibody; Sulfurylase kinase 2 antibody; SK 2 antibody; SK2) [Includes: Sulfate adenylyltransferase antibody; EC 2.7.7.4 antibody; ATP-sulfurylase antibody; Sulfate adenylate transferase antibody; SAT); Adenylyl-sulfate kinase antibody; EC 2.7.1.25 antibody; 3'-phosphoadenosine-5'-phosphosulfate synthase antibody; APS kinase antibody; Adenosine-5'-phosphosulfate 3'-phosphotransferase antibody; Adenylylsulfate 3'-phosphotransferase)] antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Bifunctional 3\'-phosphoadenosine 5\'-phosphosulfate synthase 2 protein (2-138AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，PAPSS2 Antibody (CSB-PA527262LA01HU)，的標記方式是Non-conjugated。對于PAPSS2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA527262LB01HU PAPSS2 Antibody, HRP conjugated ELISA
    FITC CSB-PA527262LC01HU PAPSS2 Antibody, FITC conjugated
    Biotin CSB-PA527262LD01HU PAPSS2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate/PAPS, the activated sulfate donor used by sulfotransferases. In mammals, PAPS is the sole source of sulfate while APS appears to only be an intermediate in the sulfate-activation pathway. Plays indirectly an important role in skeletogenesis during postnatal growth.
  • 基因功能參考文獻：
    1. In an Amish population, using expression profiling of genes within regions identified by a meta-analysis GWAS of survival to age 90, we localized PAPSS2 as a candidate gene for extended life span. These results provide novel evidence for genetic loci implicated in longevity and incorporate gene expression results from a unique population to locate positional candidates. PMID: 26896383
    2. Silencing of SULT1A1 and PAPSS2 led to a significant decrease in aristolactam-DNA levels in both cell lines following exposure to AA-I, indicating the critical role for sulfonation in the activation of AA-I in vivo Since HK-2 cells proved relatively resistant to knockdown with siRNAs PMID: 27207664
    3. Our results indicate that FGFR2 and PAPSS2 may play an important role in the regulation of magnesium homeostasis in children of European-American ancestry. PMID: 26685716
    4. Results suggest that the loss of the susceptible region on chromosome 10q, which implicates PTEN, FAS and PAPSS2 may serve as genetic predictors of PSA recurrence after radical prostatectomy. PMID: 25679447
    5. Direct in vivo evidence for the significant functional impact of mutant PAPSS2 on DHEA sulfation and androgen activation. PMID: 25594860
    6. PAPSS2-brachyolmia includes phenotypes of the conventional clinical concept of brachyolmia, the Hobaek and Toledo types, and is associated with abnormal androgen metabolism. PMID: 23824674
    7. Papss2 expression is reduced in articular cartilage following transforming growth factor-beta administration. PMID: 22394585
    8. PAPSS2 is the disease gene for an autosomal recessive brachyolmia. PMID: 22791835
    9. Unusual localisation signals of both PAPS synthase isoforms, are described. PMID: 22242175
    10. Thirty-seven novel SNPs in the PAPSS2 gene and in two intergenic regions on chromosomes 2q33.1 and 18p11.32 were associated with exercise participation. PMID: 19727025
    11. Transcriptional regulation of human 3'-phosphoadenosine 5'-phosphosulphate synthase 2. PMID: 11931653

    顯示更多

    收起更多

  • 相關疾病：
    Brachyolmia type 4 with mild epiphyseal and metaphyseal changes (BCYM4)
  • 蛋白家族：
    APS kinase family; Sulfate adenylyltransferase family
  • 組織特異性：
    Expressed in cartilage and adrenal gland.
  • 數據庫鏈接：

    HGNC: 8604

    OMIM: 603005

    KEGG: hsa:9060

    STRING: 9606.ENSP00000406157

    UniGene: Hs.524491



主站蜘蛛池模板： 国产一区二区三区四区精华| 中文字幕无码中文字幕有码| 老司机无码精品a| 99久久无色码中文字幕人妻| 亚洲人成黄网站69影院| 亚洲精品一区二区三区四区乱码| 亚洲精品国产精品乱码视色 | 国产sm调教折磨视频失禁| 亚洲成av人片在www鸭子| 亚洲国产精品自在拍在线播放蜜臀| 亚洲精品成人网站在线观看| 精品高潮呻吟99av无码视频| 国产综合色在线视频区| 中文字幕无码av正片| 52综合精品国产二区无码| 国产午夜精品一区二区三区四区 | av大片在线无码永久免费| 精品一区二区三区国产在线观看| 99精品国产福久久久久久| 国产精品美女被遭强扒开双腿| 欧美亚洲精品中文字幕乱码| 蜜色欲多人av久久无码| 强行从后面挺进人妻| 一本大道久久久久精品嫩草| 精品无码av不卡一区二区三区| 久久久久久无码精品人妻a片软件 999久久久精品国产消防器材 | 成人欧美一区二区三区视频| 色偷偷av亚洲男人的天堂| 国产免费久久久久久无码| 黄网站色成年片在线观看| 久久国产福利播放| 国产又大又黑又粗免费视频| 男人扒开女人双腿猛进视频| 999成人精品视频在线| 亚洲精品毛片一区二区三区| 亚洲不卡中文字幕无码| 国产xxxx69真实实拍| 人妻精品久久无码区| av片在线观看| 欧美精品乱码99久久蜜桃| 国产99视频精品免费视频76|