在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Beclin-1-like protein 1 (BECN1L1)

Recombinant Human Beclin-1-like protein 1 (BECN1L1)

  • 中文名稱：
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號：
    CSB-YP427931HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號：
    CSB-EP427931HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號：
    CSB-EP427931HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號：
    CSB-BP427931HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號：
    CSB-MP427931HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    BECN2; BECN1L1; BECN1P1Beclin-2; Beclin-1 autophagy-related pseudogene 1; Beclin-1-like protein 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-431
  • 氨基酸序列
    MSSIRFLCQR CHQALKLSGS SESRSLPAAP APTSGQAEPG DTREPGVTTR EVTDAEEQQD GASSRSPPGD GSVSKGHANI FTLLGELGAM HMLSSIQKAA GDIFDIVSGQ AVVDHPLCEE CTDSLLEQLD IQLALTEADS QNYQRCLETG ELATSEDEAA ALRAELRDLE LEEARLVQEL EDVDRNNARA AADLQAAQAE AAELDQQERQ HYRDYSALKR QQLELLDQLG NVENQLQYAR VQRDRLKEIN CFTATFEIWV EGPLGVINNF RLGRLPTVRV GWNEINTAWG QAALLLLTLA NTIGLQFQRY RLIPCGNHSY LKSLTDDRTE LPLFCYGGQD VFLNNKYDRA MVAFLDCMQQ FKEEAEKGEL GLSLPYGIQV ETGLMEDVGG RGECYSIRTH LNTQELWTKA LKFMLINFKW SLIWVASRYQ K
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1.
  • 基因功能參考文獻：
    1. Further data showed that reactive oxygen species-c-Jun activation by HBx resulted in the release of beclin-1 from its association with beclin-2 to form a complex with VPS34, thus enhancing autophagosome formation. PMID: 28515304
    2. polar BECN2 CCD interface residues result in a metastable homodimer, facilitating dissociation, but enable better interactions with polar ATG14 residues stabilizing the BECN2:ATG14 heterodimer. PMID: 28218432
    3. Both transfected and endogenous beclin 2 coimmunoprecipitated with vGPCR. Beclin 2 overexpression decreased HA-vGPCR steady-state levels. It regulates vGPCR levels by a lysosomal degradation pathway. PMID: 26929373
    4. distinct patterns of Beclin 1 and Beclin 2 were associated with aggressive clinical outcomes. Beclin 1 overexpression, as well as Beclin 2 overexpression and depletion, contributed to tumor growth. PMID: 26506105
    5. Study identified a previously uncharacterized mammalian-specific protein, Beclin 2, which, like Beclin 1, functions in autophagy and interacts with class III PI3K complex components.[Beclin 2] PMID: 23954414

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Beclin family
  • 組織特異性：
    Present in fetal and adult brain (at protein level).
  • 數據庫鏈接：

    HGNC: 38606

    OMIM: 615687

    KEGG: hsa:441925

    UniGene: Hs.731347



主站蜘蛛池模板： 国产熟妇人妻精品一区二区动漫| 亚洲熟妇av一区| 男女做爰猛烈啪啪吃奶伸舌头下载 | 亚洲精品中文字幕一区二区三区| 99久久人人爽亚洲精品美女| 欧美老妇交乱视频在线观看| 女人爽到高潮免费视频大全 | 无码国产精品一区二区免费vr| 人妻人人澡人人添人人爽人人玩| 国产经典三级av在线播放| 日本一区不卡高清更新二区 | 鲁大师在线视频播放免费观看| 久久国产精品精品国产色婷婷| 桃花综合久久久久久久久久网| 国产超碰人人爽人人做av| 国产成人综合久久免费| 少妇av射精精品蜜桃专区| 国产品无码一区二区三区在线| 狂野欧美性猛xxxx乱大交| 中文字幕一二三区波多野结衣| 国产人在线成免费视频| 日韩欧美群交p片內射中文| 久久人妻少妇嫩草av无码专区| 无码中文字幕日韩专区| 尤物yw午夜国产精品大臿蕉| 性无码专区一色吊丝中文字幕| 久久精品伊人久久精品伊人| 亚洲一区二区三区影院| 国产免国产免‘费| 久久久久国产精品人妻aⅴ毛片| 久久久久久久曰本精品免费看| 秋霞av鲁丝片一区二区| 国产男女爽爽爽免费视频| 久久精品亚洲一区二区三区浴池| 国产亚洲精品美女在线| 玩50岁四川熟女大白屁股直播| 粉嫩小泬无遮挡久久久久久| 色依依av在线| 国产mv在线天堂mv免费观看| 18岁日韩内射颜射午夜久久成人| 久久国内精品自在自线400部|