在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Beclin-1-like protein 1 (BECN1L1)

Recombinant Human Beclin-1-like protein 1 (BECN1L1)

  • 中文名稱：
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號：
    CSB-YP427931HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號：
    CSB-EP427931HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號：
    CSB-EP427931HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號：
    CSB-BP427931HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號：
    CSB-MP427931HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    BECN2; BECN1L1; BECN1P1Beclin-2; Beclin-1 autophagy-related pseudogene 1; Beclin-1-like protein 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-431
  • 氨基酸序列
    MSSIRFLCQR CHQALKLSGS SESRSLPAAP APTSGQAEPG DTREPGVTTR EVTDAEEQQD GASSRSPPGD GSVSKGHANI FTLLGELGAM HMLSSIQKAA GDIFDIVSGQ AVVDHPLCEE CTDSLLEQLD IQLALTEADS QNYQRCLETG ELATSEDEAA ALRAELRDLE LEEARLVQEL EDVDRNNARA AADLQAAQAE AAELDQQERQ HYRDYSALKR QQLELLDQLG NVENQLQYAR VQRDRLKEIN CFTATFEIWV EGPLGVINNF RLGRLPTVRV GWNEINTAWG QAALLLLTLA NTIGLQFQRY RLIPCGNHSY LKSLTDDRTE LPLFCYGGQD VFLNNKYDRA MVAFLDCMQQ FKEEAEKGEL GLSLPYGIQV ETGLMEDVGG RGECYSIRTH LNTQELWTKA LKFMLINFKW SLIWVASRYQ K
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1.
  • 基因功能參考文獻：
    1. Further data showed that reactive oxygen species-c-Jun activation by HBx resulted in the release of beclin-1 from its association with beclin-2 to form a complex with VPS34, thus enhancing autophagosome formation. PMID: 28515304
    2. polar BECN2 CCD interface residues result in a metastable homodimer, facilitating dissociation, but enable better interactions with polar ATG14 residues stabilizing the BECN2:ATG14 heterodimer. PMID: 28218432
    3. Both transfected and endogenous beclin 2 coimmunoprecipitated with vGPCR. Beclin 2 overexpression decreased HA-vGPCR steady-state levels. It regulates vGPCR levels by a lysosomal degradation pathway. PMID: 26929373
    4. distinct patterns of Beclin 1 and Beclin 2 were associated with aggressive clinical outcomes. Beclin 1 overexpression, as well as Beclin 2 overexpression and depletion, contributed to tumor growth. PMID: 26506105
    5. Study identified a previously uncharacterized mammalian-specific protein, Beclin 2, which, like Beclin 1, functions in autophagy and interacts with class III PI3K complex components.[Beclin 2] PMID: 23954414

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Beclin family
  • 組織特異性：
    Present in fetal and adult brain (at protein level).
  • 數據庫鏈接：

    HGNC: 38606

    OMIM: 615687

    KEGG: hsa:441925

    UniGene: Hs.731347



主站蜘蛛池模板： 亚洲一区在线日韩在线尤物| 99蜜桃在线观看免费视频网站| 伊在人天堂亚洲香蕉精品区| 人人爽天天碰狠狠添| 内射女校花一区二区三区| 日韩一区二区a片免费观看| 波多野结衣av一区二区全免费观看| 午夜福利18以下勿进免费| av天堂永久资源网亚洲高清| 亚洲高清专区日韩精品| 天天爽天天爽天天片a| 草草久久久无码国产专区| 国产精品国产免费无码专区不卡 | 五月婷六月婷婷俺也去| 国语对白嫖老妇胖老太| 国产在线精品一区二区中文| 国产成人无码区免费内射一片色欲 | 高清国产亚洲欧洲av综合一区| 无码国内精品久久综合88| 久久一日本道色综合久久| 亚洲伊人丝袜精品久久| 亚洲日本va中文字幕人妖| 免费人成激情视频在线观看冫| 奇米精品视频一区二区三区| 国产亚洲精品久久久久9999| 99久久伊人精品综合观看| 无码国产伦一区二区三区视频| 久在线精品视频线观看| 免费人成激情视频在线观看| 日产精品久久久久久久| 国产精品永久免费视频| 无码精品国产一区二区免费| 色八区人妻在线视频免费 | 国产真人无遮挡作爱免费视频| 成人高潮视频在线观看| 免费人成在线观看网站品爱网| 国产女人18毛片水真多| 色偷偷88888欧美精品久久久| 肉感饱满中年熟妇日本| 国产aⅴ精品一区二区三区| 亚洲 另类 熟女 字幕|