在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Beclin-1-like protein 1 (BECN1L1)

  • 中文名稱:
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號:
    CSB-YP427931HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號:
    CSB-EP427931HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號:
    CSB-EP427931HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號:
    CSB-BP427931HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Beclin-1-like protein 1(BECN1L1)
  • 貨號:
    CSB-MP427931HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    BECN2; BECN1L1; BECN1P1Beclin-2; Beclin-1 autophagy-related pseudogene 1; Beclin-1-like protein 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-431
  • 氨基酸序列
    MSSIRFLCQR CHQALKLSGS SESRSLPAAP APTSGQAEPG DTREPGVTTR EVTDAEEQQD GASSRSPPGD GSVSKGHANI FTLLGELGAM HMLSSIQKAA GDIFDIVSGQ AVVDHPLCEE CTDSLLEQLD IQLALTEADS QNYQRCLETG ELATSEDEAA ALRAELRDLE LEEARLVQEL EDVDRNNARA AADLQAAQAE AAELDQQERQ HYRDYSALKR QQLELLDQLG NVENQLQYAR VQRDRLKEIN CFTATFEIWV EGPLGVINNF RLGRLPTVRV GWNEINTAWG QAALLLLTLA NTIGLQFQRY RLIPCGNHSY LKSLTDDRTE LPLFCYGGQD VFLNNKYDRA MVAFLDCMQQ FKEEAEKGEL GLSLPYGIQV ETGLMEDVGG RGECYSIRTH LNTQELWTKA LKFMLINFKW SLIWVASRYQ K
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1.
  • 基因功能參考文獻:
    1. Further data showed that reactive oxygen species-c-Jun activation by HBx resulted in the release of beclin-1 from its association with beclin-2 to form a complex with VPS34, thus enhancing autophagosome formation. PMID: 28515304
    2. polar BECN2 CCD interface residues result in a metastable homodimer, facilitating dissociation, but enable better interactions with polar ATG14 residues stabilizing the BECN2:ATG14 heterodimer. PMID: 28218432
    3. Both transfected and endogenous beclin 2 coimmunoprecipitated with vGPCR. Beclin 2 overexpression decreased HA-vGPCR steady-state levels. It regulates vGPCR levels by a lysosomal degradation pathway. PMID: 26929373
    4. distinct patterns of Beclin 1 and Beclin 2 were associated with aggressive clinical outcomes. Beclin 1 overexpression, as well as Beclin 2 overexpression and depletion, contributed to tumor growth. PMID: 26506105
    5. Study identified a previously uncharacterized mammalian-specific protein, Beclin 2, which, like Beclin 1, functions in autophagy and interacts with class III PI3K complex components.[Beclin 2] PMID: 23954414

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Beclin family
  • 組織特異性:
    Present in fetal and adult brain (at protein level).
  • 數據庫鏈接:

    HGNC: 38606

    OMIM: 615687

    KEGG: hsa:441925

    UniGene: Hs.731347



主站蜘蛛池模板: 人妻少妇中文字幕久久| av无码国产在线看免费网站| 亚洲成av人片无码迅雷下载| 色老板精品视频在线观看| 狠狠色婷婷久久综合频道日韩| 亚洲大尺度无码无码专线| 国产一卡2卡3卡四卡精品app| 久久久亚洲精品一区二区三区浴池| 亚洲乱码日产精品bd在线观看| 亚洲欧美成人a∨观看| 日产精品中文一区二区三区| 国产精品久久久久影院老司| 国产av无码专区亚洲awww| 亚洲精品欧美综合四区| 人妻aⅴ中文字幕无码| 少妇粉嫩小泬白浆流出| 最近免费中文字幕中文高清百度| 手机看黄av免费网址| 亚州久久久久区1区2少妇| 无遮挡又黄又刺激的视频| 9420免费高清在线观看视频| 午夜免费啪视频在线观看区| 国产精品夜色一区二区三区| 亚洲啪啪综合av一区| 亚洲综合最新无码专区| 亚洲精品国男人在线视频| 精品午夜福利无人区乱码一区| 亚洲欧洲av综合色无码| 无码中文字幕va精品影院| 被灌满精子的波多野结衣| 国产精品国产三级在线专区| 国内精品久久久久影院蜜芽| 韩日综合成人中文字幕| 业余 自由 性别 成熟偷窥| 大香伊蕉在人线国产网站首页 | 日韩免费人妻av无码专区蜜桃| 女女女女女裸体处开bbb| 免费看国产曰批40分钟| 丁香五月开心婷婷激情综合| 久久精品国产日本波多野结衣| 菠萝蜜视频在线观看入口|