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  4. Recombinant Human Band 4.1-like protein 2 (EPB41L2), partial

Recombinant Human Band 4.1-like protein 2 (EPB41L2), partial

  • 中文名稱：
    人EPB41L2重組蛋白
  • 貨號：
    CSB-YP007708HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人EPB41L2重組蛋白
  • 貨號：
    CSB-EP007708HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人EPB41L2重組蛋白
  • 貨號：
    CSB-EP007708HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人EPB41L2重組蛋白
  • 貨號：
    CSB-BP007708HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人EPB41L2重組蛋白
  • 貨號：
    CSB-MP007708HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    EPB41L2
  • Uniprot No.：
  • 別名：
    4.1 G ; 4.1G; AW555191; Band 4.1 like protein 2 ; Band 4.1-like protein 2; D10Ertd398e; DKFZp781D1972; DKFZp781H1755; E41L2_HUMAN; Epb41l2; Erythrocyte membrane protein band 4.1 like 2; Erythrocyte membrane protein band 4.1 like protein 2; Generally expressed protein 4.1; NBL2; OTTHUMP00000017197; OTTHUMP00000040262
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.
  • 基因功能參考文獻：
    1. Ca(2+)/CaM binding to GHP, and more specifically to pepG, has profound effects on other functional domains of 4.1G PMID: 23354586
    2. 4.1G protein depresses PTH-related protein receptor-mediated Gs signaling pathway by suppression of adenylyl cyclase-mediated cAMP production. PMID: 23201780
    3. A phosphoserine-dependent tethering role for protein 4.1G in lipid rafts provides insight into the unique phosphoserine-based regulation of FcgammaRI receptor signaling. PMID: 22003208
    4. PTA-1(CD226 antigen) is localized to membrane rafts and binds the carboxyl-terminal domain of isoforms of the actin-binding protein 4.1G and also can bind human discs large providing the structural basis for a regulated molecular adhesive complex PMID: 15138281
    5. An alternatively spliced 4.1G product is shown to be associated with increased Fc gamma RI binding in yeast two-hybrid assays, and to be selectively enriched in most immune cells at the transcript level. PMID: 18023480

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  • 亞細胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cell membrane.
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 3379

    OMIM: 603237

    KEGG: hsa:2037

    STRING: 9606.ENSP00000338481

    UniGene: Hs.486470



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