在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human BTB/POZ domain-containing protein KCTD12 (KCTD12)

Recombinant Human BTB/POZ domain-containing protein KCTD12 (KCTD12)

  • 中文名稱：
    人KCTD12重組蛋白
  • 貨號：
    CSB-YP842652HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人KCTD12重組蛋白
  • 貨號：
    CSB-EP842652HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人KCTD12重組蛋白
  • 貨號：
    CSB-EP842652HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人KCTD12重組蛋白
  • 貨號：
    CSB-BP842652HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人KCTD12重組蛋白
  • 貨號：
    CSB-MP842652HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    KCTD12
  • Uniprot No.：
  • 別名：
    13orf2; BTB/POZ domain-containing protein KCTD12; KCD12_HUMAN; KCTD12; KIAA1778; PFET1; Pfetin; potassium channel tetramerisation domain containing 12 USA ; Predominantly fetal expressed T1 domain
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-325
  • 氨基酸序列
    ALADSTRGL PNGGGGGGGS GSSSSSAEPP LFPDIVELNV GGQVYVTRRC TVVSVPDSLL WRMFTQQQPQ ELARDSKGRF FLDRDGFLFR YILDYLRDLQ LVLPDYFPER SRLQREAEYF ELPELVRRLG APQQPGPGPP PSRRGVHKEG SLGDELLPLG YSEPEQQEGA SAGAPSPTLE LASRSPSGGA AGPLLTPSQS LDGSRRSGYI TIGYRGSYTI GRDAQADAKF RRVARITVCG KTSLAKEVFG DTLNESRDPD RPPERYTSRY YLKFNFLEQA FDKLSESGFH MVACSSTGTC AFASSTDQSE DKIWTSYTEY VFCRE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
  • 基因功能參考文獻：
    1. KCTD12 may exert its inhibitory role in ESCC through the suppression of WNT /NOTCH, stem cell factors, and chromatin remodelers and can be introduced as an efficient therapeutic marker. PMID: 30157793
    2. our study demonstrate that KCTD12 binds to CDC25B and activates CDK1 and Aurora A to facilitate the G2/M transition and promote tumorigenesis and that Aurora A phosphorylates KCTD12 at serine 243 to trigger a positive feedback loop, thereby potentiating the effects of KCTD12. Thus, the KCTD12-CDC25B-CDK1-Aurora A axis has important implications for cancer diagnoses and prognoses. PMID: 28869606
    3. Low KCTD12 expression is associated with uveal melanoma. PMID: 28000887
    4. Studies determined that KCTD12 plays an important role in the tumorigenesis of colorectal cancer progression via activation of the ERK signaling pathway. PMID: 26847701
    5. N-terminal domain of KCTD12 assumes an alpha/beta structure, whereas the C-terminal domain is predominantly characterized by a beta-structure. PMID: 23996491
    6. KCTD12 is a useful and reliable biomarker for both the diagnosis and prognosis of gastrointestinal stromal tumor. PMID: 23290008
    7. This study provided that kctd12 are associated with Bipolar I in the Han Chinese population. PMID: 20386566
    8. novel human gene, designated PFET1 (predominantly fetal expressed T1 domain) present in a variety of fetal organs, with highest expression levels in the cochlea and brain PMID: 15357420
    9. Pfetin is a powerful prognostic marker for gastrointestinal stromal tumors. PMID: 18347171

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane.
  • 組織特異性：
    Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung.
  • 數據庫鏈接：

    HGNC: 14678

    OMIM: 610521

    KEGG: hsa:115207

    STRING: 9606.ENSP00000317141

    UniGene: Hs.644125



主站蜘蛛池模板： 色欲色香天天天综合无码www| 国产成人精品日本亚洲999| 人妻少妇熟女javhd| 天天躁日日躁狠狠躁av麻豆| 久久精品国产精品青草| 午夜爽爽爽男女污污污网站| 国产成人综合亚洲看片| 亚洲成av人片在线观看无码 | 伊人久久大香线焦av综合影院 | 国产精品免费看久久久无码| 亚洲aⅴ天堂av天堂无码麻豆| 中文字幕亚洲无线码一区女同| 黑人强伦姧人妻久久| 国产成人愉拍精品| 国产真实乱对白精彩久久老熟妇女| 国产精品怡红院在线观看| 男女啪啪抽搐高潮动态图| 茄子视频国产在线观看| 中文天堂网www新版资源在线| 国产精品久久久久久久久动漫 | 国产丝袜在线精品丝袜不卡| 中文字幕人妻丝袜成熟乱 | 午夜成人理论福利片| 大帝av在线一区二区三区| 亚洲大尺度专区无码浪潮av| 国产成人精品一区二区三区| 欧美在线看片a免费观看 | 国产欧美一区二区精品仙草咪| 国产精品中文久久久久久久| 久久www免费人成精品| 亚洲综合色婷婷六月丁香宅男大增 | 亚洲一二三四2021不卡| 少妇爱做高清免费视频| 亚洲 欧美 综合 另类 中字| 乱色欧美激惰| 一个色综合国产色综合| 日本边添边摸边做边爱边| 亚洲综合天堂av网站在线观看| 99国产精品久久久蜜芽| 中文字幕v亚洲日本在线电影| 久久99精品久久久久子伦|