在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KCTD12 Antibody

KCTD12 Antibody

  • 中文名稱：
    KCTD12兔多克隆抗體
  • 貨號：
    CSB-PA012108GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    KCTD12
  • 別名：
    tibody; BTB/POZ domain-containing protein KCTD12 antibody; KCD12_HUMAN antibody; KCTD12 antibody; KIAA1778 antibody; PFET1 antibody; Pfetin antibody; potassium channel tetramerisation domain containing 12 USA antibody; Predominantly fetal expressed T1 domain antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human KCTD12
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
  • 基因功能參考文獻：
    1. KCTD12 may exert its inhibitory role in ESCC through the suppression of WNT /NOTCH, stem cell factors, and chromatin remodelers and can be introduced as an efficient therapeutic marker. PMID: 30157793
    2. our study demonstrate that KCTD12 binds to CDC25B and activates CDK1 and Aurora A to facilitate the G2/M transition and promote tumorigenesis and that Aurora A phosphorylates KCTD12 at serine 243 to trigger a positive feedback loop, thereby potentiating the effects of KCTD12. Thus, the KCTD12-CDC25B-CDK1-Aurora A axis has important implications for cancer diagnoses and prognoses. PMID: 28869606
    3. Low KCTD12 expression is associated with uveal melanoma. PMID: 28000887
    4. Studies determined that KCTD12 plays an important role in the tumorigenesis of colorectal cancer progression via activation of the ERK signaling pathway. PMID: 26847701
    5. N-terminal domain of KCTD12 assumes an alpha/beta structure, whereas the C-terminal domain is predominantly characterized by a beta-structure. PMID: 23996491
    6. KCTD12 is a useful and reliable biomarker for both the diagnosis and prognosis of gastrointestinal stromal tumor. PMID: 23290008
    7. This study provided that kctd12 are associated with Bipolar I in the Han Chinese population. PMID: 20386566
    8. novel human gene, designated PFET1 (predominantly fetal expressed T1 domain) present in a variety of fetal organs, with highest expression levels in the cochlea and brain PMID: 15357420
    9. Pfetin is a powerful prognostic marker for gastrointestinal stromal tumors. PMID: 18347171

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane.
  • 組織特異性：
    Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung.
  • 數據庫鏈接：

    HGNC: 14678

    OMIM: 610521

    KEGG: hsa:115207

    STRING: 9606.ENSP00000317141

    UniGene: Hs.644125



主站蜘蛛池模板： 欧美黑人又粗又大久久久| 忍着娇喘人妻被中出中文字幕| 午夜福利视频极品国产83| 天堂在/线资源中文在线8| 大伊香蕉精品视频在线| 综合久久给合久久狠狠狠97色| 国产精品免费一区二区三区四区| 丁香五月亚洲综合深深爱| 国产亚洲日本精品无码| 久久精品aⅴ无码中文字字幕| 欧美顶级少妇做爰hd| 色两性网欧美| 强辱丰满人妻hd中文字幕| 久久 国产 尿 小便 嘘嘘| 亚洲色大成网站www永久在线观看 亚洲日韩国产精品无码av | 吃奶摸下高潮60分钟免费视频| 久久国产福利国产秒拍飘飘网| 精品欧洲av无码一区二区| 欧美激情乱人伦| 亚洲精品色播一区二区| 无码抽搐高潮喷水流白浆| 久久99精品久久久大学生| 国产精品成人国产乱| 亚洲中文字幕aⅴ无码天堂| 国产女主播白浆在线看 | 内射囯产旡码丰满少妇| 在线 | 一区二区三区| 久久精品国产久精国产果冻传媒| 国产精品18久久久久久欧美| 欧美巨大巨粗黑人性aaaaaa| 免费夜色污私人影院在线观看| 色婷婷综合和线在线| 亚洲国产精品无码专区影院| 特黄特色大片免费播放器图片| 久久精品国产99国产精品导航| 亚洲精品日本一区二区三区| 国模小黎自慰337p人体| 国产午夜毛片v一区二区三区| 久久精品女人天堂av麻| 国产萌白酱喷水视频在线播放| 欧美牲交a欧美牲交aⅴ|