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  4. Recombinant Human Arginine-glutamic acid dipeptide repeats protein (RERE), partial

Recombinant Human Arginine-glutamic acid dipeptide repeats protein (RERE), partial

  • 中文名稱：
    人RERE重組蛋白
  • 貨號：
    CSB-YP879073HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人RERE重組蛋白
  • 貨號：
    CSB-EP879073HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人RERE重組蛋白
  • 貨號：
    CSB-EP879073HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人RERE重組蛋白
  • 貨號：
    CSB-BP879073HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人RERE重組蛋白
  • 貨號：
    CSB-MP879073HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    RERE
  • Uniprot No.：
  • 別名：
    1110033A15Rik; AI414665; ARG; arginine glutamic acid dipeptide (RE) repeats; arginine glutamic acid dipeptide repeats; Arginine glutamic acid dipeptide repeats protein; Arginine-glutamic acid dipeptide repeats protein; ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE; ARP; ATN1L; Atr2; atrophin 1 like; Atrophin 1 like protein; Atrophin 1 related protein; atrophin 2; atrophin related protein; ATROPHIN-1-ASSOCIATED PROTEIN; Atrophin-1-like protein; Atrophin-1-related protein; atrophin-2; ATROPHIN-RELATED PROTEIN; AW742570; DNB1; FLJ38775; KIAA0458; mKIAA0458; NEDBEH; OTTHUMP00000001701; Rere; RERE_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
  • 基因功能參考文獻：
    1. suggest that mutations in RERE cause a genetic syndrome and that haploinsufficiency of RERE might be sufficient to cause many of the phenotypes associated with proximal 1p36 deletions PMID: 27087320
    2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    3. Observational study of gene-disease association. (HuGE Navigator) PMID: 18597038
    4. The mouse ortholog of RERE is required for embryonic development PMID: 14645126
  • 相關疾病：
    Neurodevelopmental disorder with or without anomalies of the brain, eye, or heart (NEDBEH)
  • 亞細胞定位：
    Nucleus. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.
  • 組織特異性：
    Widely expressed. Expressed in tumor cell lines.
  • 數據庫鏈接：

    HGNC: 9965

    OMIM: 605226

    KEGG: hsa:473

    STRING: 9606.ENSP00000338629

    UniGene: Hs.463041



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