在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Arfaptin-2 (ARFIP2)

  • 中文名稱:
    Recombinant Human Arfaptin-2(ARFIP2)
  • 貨號:
    CSB-YP002003HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Arfaptin-2(ARFIP2)
  • 貨號:
    CSB-EP002003HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Arfaptin-2(ARFIP2)
  • 貨號:
    CSB-EP002003HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Arfaptin-2(ARFIP2)
  • 貨號:
    CSB-BP002003HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Arfaptin-2(ARFIP2)
  • 貨號:
    CSB-MP002003HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ARFIP2
  • Uniprot No.:
  • 別名:
    ADP ribosylation factor interacting protein 2; ADP-ribosylation factor-interacting protein 2; Arfaptin 2; Arfaptin-2; ARFIP2; ARFP2_HUMAN; FLJ18046; FLJ18697; FLJ99239; Partner of RAC1; POR1; Protein POR1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-341
  • 氨基酸序列
    MTDGILGKAA TMEIPIHGNG EARQLPEDDG LEQDLQQVMV SGPNLNETSI VSGGYGGSGD GLIPTGSGRH PSHSTTPSGP GDEVARGIAG EKFDIVKKWG INTYKCTKQL LSERFGRGSR TVDLELELQI ELLRETKRKY ESVLQLGRAL TAHLYSLLQT QHALGDAFAD LSQKSPELQE EFGYNAETQK LLCKNGETLL GAVNFFVSSI NTLVTKTMED TLMTVKQYEA ARLEYDAYRT DLEELSLGPR DAGTRGRLES AQATFQAHRD KYEKLRGDVA IKLKFLEENK IKVMHKQLLL FHNAVSAYFA GNQKQLEQTL QQFNIKLRPP GAEKPSWLEE Q
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2. Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site. In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG.
  • 基因功能參考文獻:
    1. The data indicate that arfaptin 2 is the first molecule to regulate NF-kappaB signaling by interacting with the functional IkappaB kinase complex but not by direct inhibiting IKKbeta phosphorylation. PMID: 26296658
    2. both Arf1 activation and high membrane curvature are required for efficient recruitment of Arfaptin2 to membranes PMID: 23638170
    3. The binding of arfaptin1, but not arfaptin2, to PI(4)P is regulated by protein kinase D (PKD) mediated phosphorylation at Ser100 within the AH. PMID: 23695357
    4. The Arl1.Arfaptin-2 BAR structure suggests that one of the two Arl1 molecules competes with Rac1, which binds to the concave face of the Arfaptin-2 BAR homodimer and may hinder its membrane association. PMID: 22679020
    5. arfaptin 2 is involved in regulating huntingtin protein aggregation PMID: 11854752
    6. arfaptin 2 phosphorylation at Ser260 by Akt inhibits PolyQ-huntingtin-induced toxicity by rescuing proteasome impairment PMID: 15809304

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.
  • 數據庫鏈接:

    HGNC: 17160

    OMIM: 601638

    KEGG: hsa:23647

    STRING: 9606.ENSP00000254584

    UniGene: Hs.732203



主站蜘蛛池模板: 久久久久国产精品人妻aⅴ牛牛| 国产情侣久久久久aⅴ免费| 无码国产精品一区二区免费虚拟vr| 中文天堂最新版在线www | 色舞月亚洲综合一区二区| 免费很黄无遮挡的视频| 国产精品第12页| 亚洲情xo亚洲色xo无码| 变态另类先锋影音| 手机真实国产乱子伦对白视频| 亚洲第一成人网站| 男人扒开女人内裤强吻桶进去| 国产在线观看免费视频软件 | 国产人无码a在线西瓜影音| 黑人大战欲求不满人妻| 人人妻人人澡人人爽秒播| 日本特黄特色特爽大片| 黑人尾随强伦姧人妻爽翻天| 亚洲精品久久久久一区二区三区 | 性欧美性另类巨大| 精品国产一区二区三区av色诱 | 欧美日产欧美日产国产精品| 中文字幕一区二区三区四区五区| 日本大片免a费观看视频三区| 成 人 亚洲 综合天堂| 成在人线无码aⅴ免费视频| 成人h动漫精品一区二区无码 | 日本熟妇浓毛hdsex| 天天躁夜夜踩很很踩2022| 亚欧成人中文字幕一区| 国产精品视频一区二区三区不卡| 久久久久国产综合av天堂| 中文无码精品a∨在线观看| 十八禁无码免费网站| 黑森林福利视频导航| 2021精品国夜夜天天拍拍| 九九热爱视频精品视频16 | 成人免费大片黄在线观看com| 中文字幕无码精品亚洲35| 国产精品多p对白交换绿帽| 日本老熟妇乱子伦视频|