在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Ammonium transporter Rh type A (RHAG RH50)

Recombinant Human Ammonium transporter Rh type A (RHAG RH50)

  • 中文名稱：
  • 貨號：
    CSB-YP2254HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-EP2254HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-EP2254HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-BP2254HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-MP2254HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    RHAG
  • Uniprot No.：
  • 別名：
    Ammonium transporter Rh type A; Erythrocyte membrane glycoprotein Rh50; Erythrocyte plasma membrane 50 kDa glycoprotein; Rh50A; Rhesus blood group family type A glycoprotein; Rh family type A glycoprotein; Rh type A glycoprotein; Rhesus blood group-associated ammonia channel; Rhesus blood group-associated glycoprotein; CD antigen CD241; RHAG RH50
  • 種屬：
    Homo sapiens (Human)
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

相關產品

靶點詳情

  • 功能：
    Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Involved in ammonia transport across the erythrocyte membrane. Seems to act in monovalent cation transport.
  • 基因功能參考文獻：
    1. A novel nucleotide deletion in RHAG allele identified in a Chinese Rhnull individual. PMID: 29266289
    2. Case Report: complex RHAG genotype including a novel de novo mutation associated with overhydrated stomatocytosis. PMID: 29559519
    3. These results indicated that the 540C>A nonsense mutation in RHAG gene caused the regulator type of Rhnull phenotype in a Chinese individual. PMID: 28063760
    4. novel allele in a Brazilian pregnant woman encoding the Rhnull phenotype due to a change in RHAG exon2 c.310C>T, which leads to a premature stop codon (Gln104Stop). PMID: 26175207
    5. We characterized ammonia and ammonium (NH3/NH4 (+)) transport by the rhesus-associated (Rh) glycoproteins RhAG, Rhbg, and Rhcg expressed in Xenopus oocytes. We used ion-selective microelectrodes and two-electrode voltage clamp to measure changes in intracellular pH, surface pH, and whole cell currents induced by NH3/NH4 (+) and methyl amine/ammonium (MA/MA(+)). PMID: 26354748
    6. A new Rh null allele (RHAG*01N.13) of the regulator type found in a consanguineous French-speaking quebecers'family. PMID: 25296744
    7. RhAG, RhBG and RhCG-exhibit significant permeability to NH3 and show for the first time that RhBG and RhCG can conduct CO2. PMID: 24077989
    8. Data from differentiating cultured erythroid precursor cells suggest that RhAG knockdown abolishes Rh blood group expression (RhoD [ras homolog family member D]; ICAM4 [intercellular adhesion molecule 4]; CD47 Rh-related antigen) in erythroid cells. PMID: 23417980
    9. Substitution of GPB with Gp.Mur significantly reduced the expression of Rh antigen and RhAG on the Mi.III(+/+) erythrocyte membrane PMID: 21883272
    10. Results provide new insights into the functional impact of the Phe65Ser mutation in RhAG. PMID: 22012326
    11. that the 672C>A missense mutation in the RHAG gene could result in Rh(null) of the regulator type, and the single-amino-acid change (Ser to Arg) might be critical for assembly of the Rh antigen complex within the membrane PMID: 21682734
    12. The results provide new insight into RhAG stomatocytosis mutant F65S as a combined loss-of-function/gain-of-function mutation for methylammonium/methylammonium+ transport PMID: 21849667
    13. identification as a mammalian ammonium transporter PMID: 11861637
    14. Cell-surface expression of RhD blood group polypeptide is posttranscriptionally regulated by the RhAG glycoprotein. PMID: 12130520
    15. interactions of CD47 and RhAG and the Rh proteins with one another and with the cytoskeleton of intact erythrocytes PMID: 12393442
    16. RhAG functions as a NH(4)(+)/H(+) exchanger; ammonium transport is coupled to the H(+) gradient PMID: 14966114
    17. RhAG facilitates CH(3)NH(2)/NH(3) movement across the RBC membrane and represents a potential example of a gas channel in mammalian cells. PMID: 15572441
    18. The combination of these polymorphisms could not be found in any control individuals, suggesting that they might be involved in genetic predisposition to migraine in this family. PMID: 16378686
    19. RhAG-mediated transport is an electroneutral process that is driven by the NH4+ concentration and the transmembrane H+ gradient, effectively exchanging NH4+ for H+ in a process that results in transport of net NH3. PMID: 16563829
    20. RhAG expression enhanced the ammonium-induced initial alkalinization (related to NH3 influx)& secondary acidification (related to NH4+ influx). Sub-millimolar NH4+ concentrations induced inward currents in voltage-clamped RhAG-expressing cells. PMID: 16564724
    21. Review. RhAG plays a major role in the NH3 conductance of erythrocytes, but probably not in CO2 transport. PMID: 16574458
    22. Rh protein, presumably the Rh-associated glycoprotein RhAG, possesses a gas channel that allows passage of CO2 in addition to NH3 PMID: 17712059
    23. Reduced amounts of Rh-associated glycoprotein is associated with overhydrated hereditary stomatocytosis. PMID: 18931342
    24. gas channels exhibit selectivity for CO(2) vs. NH(3) permeability, demonstrating the sequence AQP4 congruent with AQP5 > AQP1 > AmtB > RhAG. PMID: 19273840

    顯示更多

    收起更多

  • 相關疾病：
    Regulator type Rh-null hemolytic anemia (RHN); Overhydrated hereditary stomatocytosis (OHST)
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Ammonium transporter (TC 2.A.49) family, Rh subfamily
  • 組織特異性：
    Erythrocytes.
  • 數據庫鏈接：

    HGNC: 10006

    OMIM: 180297

    KEGG: hsa:6005

    STRING: 9606.ENSP00000360217

    UniGene: Hs.120950



主站蜘蛛池模板： 97色伦综合在线欧美视频| 成在线人免费视频一区二区| 美女张开腿黄网站免费| 国产午夜精品一区二区三区嫩草| 99在线精品免费视频九九视| 亚洲电影天堂av2017| 亚洲国产成人无码av在线播放| 国产网红女主播精品视频| 亚洲日韩欧洲乱码av夜夜摸| 免费无码又爽又刺激高潮| 国产97超碰人人做人人爱| 国产成人无码精品久久涩吧| 免费午夜男女高清视频| 免费欧洲美女牲交视频| 国产互换人妻hd| 99国产成人精品视频| 国产精品 精品国内自产拍| 丰满五十六十老熟女hd| 国产午夜鲁丝无码拍拍| 天天躁日日躁狠狠躁性色av| 国产精品久久久一区二区三区| 国产精品露脸国语对白| 中文字幕人成乱码熟女香港| 国产农村毛卡片| 国产精品永久久久久久久久久| 99热精品久久只有精品| 欧美 日韩 亚洲 在线| 精品一区二区三区影院在线午夜| 夜夜躁狠狠躁日日躁视频| 人妻丰满熟妞av无码区| 国产初高中生粉嫩无套第一次| 牲交a欧美牲交aⅴ免费一| 国产美女在线精品免费观看网址| 国产suv精品一区二人妻| 国产免费看又黄又大又污的胸 | 男女裸交免费无遮挡全过程| 国产情侣真实54分钟在线| 亚洲国产成人精品无码区一本| 久9视频这里只有精品| 性欧美疯狂xxxxbbbb| 国产精品久免费的黄牛仔短裤|