在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Ammonium transporter Rh type A (RHAG RH50)

Recombinant Human Ammonium transporter Rh type A (RHAG RH50)

  • 中文名稱：
  • 貨號：
    CSB-YP2254HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-EP2254HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-EP2254HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-BP2254HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
  • 貨號：
    CSB-MP2254HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    RHAG
  • Uniprot No.：
  • 別名：
    Ammonium transporter Rh type A; Erythrocyte membrane glycoprotein Rh50; Erythrocyte plasma membrane 50 kDa glycoprotein; Rh50A; Rhesus blood group family type A glycoprotein; Rh family type A glycoprotein; Rh type A glycoprotein; Rhesus blood group-associated ammonia channel; Rhesus blood group-associated glycoprotein; CD antigen CD241; RHAG RH50
  • 種屬：
    Homo sapiens (Human)
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

相關產品

靶點詳情

  • 功能：
    Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Involved in ammonia transport across the erythrocyte membrane. Seems to act in monovalent cation transport.
  • 基因功能參考文獻：
    1. A novel nucleotide deletion in RHAG allele identified in a Chinese Rhnull individual. PMID: 29266289
    2. Case Report: complex RHAG genotype including a novel de novo mutation associated with overhydrated stomatocytosis. PMID: 29559519
    3. These results indicated that the 540C>A nonsense mutation in RHAG gene caused the regulator type of Rhnull phenotype in a Chinese individual. PMID: 28063760
    4. novel allele in a Brazilian pregnant woman encoding the Rhnull phenotype due to a change in RHAG exon2 c.310C>T, which leads to a premature stop codon (Gln104Stop). PMID: 26175207
    5. We characterized ammonia and ammonium (NH3/NH4 (+)) transport by the rhesus-associated (Rh) glycoproteins RhAG, Rhbg, and Rhcg expressed in Xenopus oocytes. We used ion-selective microelectrodes and two-electrode voltage clamp to measure changes in intracellular pH, surface pH, and whole cell currents induced by NH3/NH4 (+) and methyl amine/ammonium (MA/MA(+)). PMID: 26354748
    6. A new Rh null allele (RHAG*01N.13) of the regulator type found in a consanguineous French-speaking quebecers'family. PMID: 25296744
    7. RhAG, RhBG and RhCG-exhibit significant permeability to NH3 and show for the first time that RhBG and RhCG can conduct CO2. PMID: 24077989
    8. Data from differentiating cultured erythroid precursor cells suggest that RhAG knockdown abolishes Rh blood group expression (RhoD [ras homolog family member D]; ICAM4 [intercellular adhesion molecule 4]; CD47 Rh-related antigen) in erythroid cells. PMID: 23417980
    9. Substitution of GPB with Gp.Mur significantly reduced the expression of Rh antigen and RhAG on the Mi.III(+/+) erythrocyte membrane PMID: 21883272
    10. Results provide new insights into the functional impact of the Phe65Ser mutation in RhAG. PMID: 22012326
    11. that the 672C>A missense mutation in the RHAG gene could result in Rh(null) of the regulator type, and the single-amino-acid change (Ser to Arg) might be critical for assembly of the Rh antigen complex within the membrane PMID: 21682734
    12. The results provide new insight into RhAG stomatocytosis mutant F65S as a combined loss-of-function/gain-of-function mutation for methylammonium/methylammonium+ transport PMID: 21849667
    13. identification as a mammalian ammonium transporter PMID: 11861637
    14. Cell-surface expression of RhD blood group polypeptide is posttranscriptionally regulated by the RhAG glycoprotein. PMID: 12130520
    15. interactions of CD47 and RhAG and the Rh proteins with one another and with the cytoskeleton of intact erythrocytes PMID: 12393442
    16. RhAG functions as a NH(4)(+)/H(+) exchanger; ammonium transport is coupled to the H(+) gradient PMID: 14966114
    17. RhAG facilitates CH(3)NH(2)/NH(3) movement across the RBC membrane and represents a potential example of a gas channel in mammalian cells. PMID: 15572441
    18. The combination of these polymorphisms could not be found in any control individuals, suggesting that they might be involved in genetic predisposition to migraine in this family. PMID: 16378686
    19. RhAG-mediated transport is an electroneutral process that is driven by the NH4+ concentration and the transmembrane H+ gradient, effectively exchanging NH4+ for H+ in a process that results in transport of net NH3. PMID: 16563829
    20. RhAG expression enhanced the ammonium-induced initial alkalinization (related to NH3 influx)& secondary acidification (related to NH4+ influx). Sub-millimolar NH4+ concentrations induced inward currents in voltage-clamped RhAG-expressing cells. PMID: 16564724
    21. Review. RhAG plays a major role in the NH3 conductance of erythrocytes, but probably not in CO2 transport. PMID: 16574458
    22. Rh protein, presumably the Rh-associated glycoprotein RhAG, possesses a gas channel that allows passage of CO2 in addition to NH3 PMID: 17712059
    23. Reduced amounts of Rh-associated glycoprotein is associated with overhydrated hereditary stomatocytosis. PMID: 18931342
    24. gas channels exhibit selectivity for CO(2) vs. NH(3) permeability, demonstrating the sequence AQP4 congruent with AQP5 > AQP1 > AmtB > RhAG. PMID: 19273840

    顯示更多

    收起更多

  • 相關疾病：
    Regulator type Rh-null hemolytic anemia (RHN); Overhydrated hereditary stomatocytosis (OHST)
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Ammonium transporter (TC 2.A.49) family, Rh subfamily
  • 組織特異性：
    Erythrocytes.
  • 數據庫鏈接：

    HGNC: 10006

    OMIM: 180297

    KEGG: hsa:6005

    STRING: 9606.ENSP00000360217

    UniGene: Hs.120950



主站蜘蛛池模板： 欧洲美女黑人粗性暴交| 草草影院精品一区二区三区 | 亚洲一区二区无码影院| 成人午夜福利视频后入| 狼人无码精华av午夜精品| 国产精品多p对白交换绿帽| 无码少妇高潮浪潮av久久| 舌头伸进去搅动好爽视频| 国产精品三级在线观看无码| 中文成人无码精品久久久不卡 | 又大又粗又爽18禁免费看| 老司机性色福利精品视频| 在线精品自偷自拍无码中文| 亚洲中文字幕无码中文字在线| 国产极品白嫩精品| 国产又粗又黄又爽的大片| 日本熟妇乱人伦a片免费高清| 97久久国产亚洲精品超碰热| 亚洲夜色噜噜av在线观看| 国产成人久久av免费看| 色婷婷香蕉在线一区二区| 国偷自产一区二区免费视频| 欧美国产激情18| 无码人妻aⅴ一区二区三区玉蒲团| 免费播放婬乱男女婬视频国产| 国产人妻精品午夜福利免费| 妺妺窝人体色www在线小说| 亚洲欧洲日产韩国在线看片| 国产高清在线精品一区下载| 国产欧美高清在线观看| 精品无码日韩一区二区三区不卡| 婷婷五月综合国产激情| 中国极品少妇videossexhd| 无码国产乱人伦偷精品视频| 日本人妻中文字幕乱码系列 | 成人无码影片精品久久久| 国产农村妇女aaaaa视频| 天堂岛国av无码免费无禁网站| 欧美午夜精品一区二区蜜桃| 免费的很黄很污的视频| 亚洲乱码日产精品bd|