Recombinant Human Alpha-protein kinase 2 (ALPK2), partial

中文名稱：

Recombinant Human Alpha-protein kinase 2(ALPK2) ,partial
貨號(hào)：

CSB-YP771429HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Alpha-protein kinase 2(ALPK2) ,partial
貨號(hào)：

CSB-EP771429HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Alpha-protein kinase 2(ALPK2) ,partial
貨號(hào)：

CSB-EP771429HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Alpha-protein kinase 2(ALPK2) ,partial
貨號(hào)：

CSB-BP771429HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Alpha-protein kinase 2(ALPK2) ,partial
貨號(hào)：

CSB-MP771429HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ALPK2
Uniprot No.：

Q86TB3
別名：

Alpha-protein kinase 2; ALPK2; ALPK2_HUMAN; FLJ34875; FLJ43253; Gm549; HAK; Heart alpha-protein kinase; RGD1564431
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation. Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling.
基因功能參考文獻(xiàn)：
1. Results showed that p.Q1853E variant of ALPK2, which had been accumulating in the Japanese population, induced a metastatic phenotype of colorectal tumors by disrupting ALPK2 function. PMID: 28668886
2. ALPK2 is crucial for luminal apoptosis and expression of DNA repair-related genes, possibly in the transition of normal colonic crypt to adenoma. PMID: 22641666
亞細(xì)胞定位：

Basolateral cell membrane.
蛋白家族：

Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily
組織特異性：

Expressed in developing cardiac tissue and cardiomyocytes (at protein level).
數(shù)據(jù)庫鏈接：

HGNC: 20565

KEGG: hsa:115701

STRING: 9606.ENSP00000354991

UniGene: Hs.628152