在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Alkaline ceramidase 3 (ACER3), partial

Recombinant Human Alkaline ceramidase 3 (ACER3), partial

  • 中文名稱：
    Recombinant Human Alkaline ceramidase 3(ACER3),partial
  • 貨號：
    CSB-YP001153HU1
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Alkaline ceramidase 3(ACER3),partial
  • 貨號：
    CSB-EP001153HU1
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Alkaline ceramidase 3(ACER3),partial
  • 貨號：
    CSB-EP001153HU1-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Alkaline ceramidase 3(ACER3),partial
  • 貨號：
    CSB-BP001153HU1
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Alkaline ceramidase 3(ACER3),partial
  • 貨號：
    CSB-MP001153HU1
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ACER3
  • Uniprot No.：
  • 別名：
    ACER3; APHC; PHCA; Alkaline ceramidase 3; AlkCDase 3; Alkaline CDase 3; Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; aPHC
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Endoplasmic reticulum and Golgi ceramidase that catalyzes the hydrolysis of unsaturated long-chain C18:1-, C20:1- and C20:4-ceramides, dihydroceramides and phytoceramides into sphingoid bases like sphingosine and free fatty acids at alkaline pH. Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation. Controls the generation of sphingosine in erythrocytes, and thereby sphingosine-1-phosphate in plasma. Through the regulation of ceramides and sphingosine-1-phosphate homeostasis in the brain may play a role in neurons survival and function. By regulating the levels of proinflammatory ceramides in immune cells and tissues, may modulate the inflammatory response.
  • 基因功能參考文獻(xiàn)：
    1. Our study suggests that Acer3 contributes to hepatocellular carcinoma propagation PMID: 30097213
    2. Homozygosity for the p.E33G mutation in the ACER3 gene results in inactivation of ACER3. PMID: 26792856
    3. The ACER3 deficiency resulted in decreased cell growth and colony formation, elevated apoptosis, and lower AKT signaling of leukemia cells. This study indicates that ACER3 contributes to AML pathogenesis, and suggests that alkaline ceramidase inhibition is an option to treat acute myeloid leukemia. PMID: 27470583
    4. ACER3 catalyzes the hydrolysis of unsaturated long chain ceramides and dihydroceramides and coordinates with ACER2 to regulate cell proliferation and survival PMID: 20068046
  • 亞細(xì)胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Alkaline ceramidase family
  • 組織特異性：
    Ubiquitously expressed. Highly expressed in placenta. Expressed in erythrocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16066

    KEGG: hsa:55331

    STRING: 9606.ENSP00000434480

    UniGene: Hs.23862



主站蜘蛛池模板： 蜜臀亚洲精品国产aⅴ综合第一| 在线看片人成视频免费无遮挡 | 亚洲欧美另类久久久精品能播放的| 亚洲欧洲日产国码久在线| 青青青国产在线视频在线观看| 午夜dy888国产精品影院| 亚洲精品人成无码中文毛片| 色综合99久久久无码国产精品| 天堂网www天堂在线资源| 最大胆裸体人体牲交免费| 精品国内在视频线2019| 色欲久久久天天天综合网精品| www激情内射在线看| 中国熟女仑乱hd| 一区二区视频| 四虎国产精品永久入口| 日本在线a一区视频高清视频| 精品精品国产高清a毛片| 极品熟妇大蝴蝶20p| 亚洲精品一品区二品区三区| 亚洲综合久久无码色噜噜| 伊人久久精品一区二区三区| 精品久久久久久久久中文字幕 | 亚洲精品中文字幕乱码4区| 亚洲中文字幕无码不卡电影| 四虎影视久久久免费观看| 九色精品国产成人综合网站| 久久99精品久久久久久不卡 | 日本又色又爽又黄的a片吻戏| 九九线精品视频在线观看| 少妇人妻大乳在线视频| 亚洲18色成人网站www| 白嫩无码人妻丰满熟妇啪啪区百度| 成人av一本不卡二卡| av免费网址在线观看| 久久精品国产99久久丝袜蜜桃| 欧美人与动性行为视频| 乱子伦视频在线看| 久久久亚洲欧洲日产国码606| 未满十八18禁止午夜免费网站| 久久天天躁狠狠躁夜夜2020一|