在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human All-trans-retinol dehydrogenase [NAD (+)] ADH7 (ADH7)

In Stock
  • 中文名稱:
    Recombinant Human All-trans-retinol dehydrogenase [NAD(+)] ADH7(ADH7)
  • 貨號:
    CSB-EP001362HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    ADH7
  • Uniprot No.:
  • 別名:
    ADH7; All-trans-retinol dehydrogenase [NAD(+)] ADH7; EC 1.1.1.105; Alcohol dehydrogenase class 4 mu/sigma chain; EC 1.1.1.1; Alcohol dehydrogenase class IV mu/sigma chain; Gastric alcohol dehydrogenase; Omega-hydroxydecanoate dehydrogenase ADH7; EC 1.1.1.66; Retinol dehydrogenase
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    45.5kDa
  • 表達區域:
    1-386aa
  • 氨基酸序列
    MFAEIQIQDKDRMGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTF
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation.
  • 基因功能參考文獻:
    1. These results suggest that variants near ADH7 may play a role in protection from alcohol dependence in this Mexican American cohort. PMID: 25527893
    2. Transcriptional regulatory elements of ADH7 were identified that effect gene expression. PMID: 24512552
    3. common ADH1-7 variants conferred risk for both schizophrenia in African-Americans and autism in European-Americans. PMID: 23468174
    4. The rs1573496 (ADH7) polymorphism was not associated with colorectal cancer risk overall in Western-European populations. However, the relationship between alcohol and colorectal cancer risk might be modulated by the rs1573496 (ADH7) polymorphism. PMID: 23149980
    5. The current results support the ADH7 A92G SNP as a marker for the risk of SCCHN in non-Hispanic white populations. PMID: 20336794
    6. An association between age at onset of regular alcohol use and a SNP just upstream of ADH7 (rs2654849, p = .003) was observed. PMID: 20158305
    7. ADH7 gene polymorphisms are associated with upper aerodigestive tract cancers. PMID: 19861527
    8. the ADH7 variation may contribute to the genetic component of variation in personality traits, with the risk for SD and personality traits being partially shared. PMID: 17918242
    9. A recombinational hotspot within intron 7 of the ADH7 gene were seen using 25 SNPs; haplotypes associated with inter-individual variation in the early stages of alcohol metabolism were identified. PMID: 17921519
    10. Changes in the activity of class IV ADH in the sera of patients with gastric cancer seems to be caused by release of the isoenzyme from cancer cells. PMID: 18231859
    11. Single Nucleotide Polymorphism in ADH7 gene is associated with upper aerodigestive cancer. PMID: 18500343

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Zinc-containing alcohol dehydrogenase family, Class-IV subfamily
  • 組織特異性:
    Preferentially expressed in stomach.
  • 數據庫鏈接:

    HGNC: 256

    OMIM: 600086

    KEGG: hsa:131

    STRING: 9606.ENSP00000420269

    UniGene: Hs.389



主站蜘蛛池模板: 久久久久久无码日韩欧美| 亚洲久悠悠色悠在线播放| 久久久综合九色综合88| 开心色婷婷色五月激情| 国产成人无码午夜视频在线播放 | 久久人人做人人妻人人玩精品hd| 久久人人97超碰超国产| 两性色午夜视频免费无码| 久久国语露脸国产精品电影| 超碰香蕉人人网99精品| 麻豆专媒体一区二区| 蜜臀国产在线视频| 亚洲熟妇国产熟妇肥婆| 成年无码动漫av片在线尤物| 亚洲中文无码mv| 野花社区视频www官网| 国产综合精品| 亚洲视频无码高清在线| 国产福利免费视频不卡| 午夜久久久久久禁播电影| 亲子乱av一区二区三区 | 欧美一区二区三区久久综| 亚欧洲乱码视频一二三区| 日本一区二区三区免费更新不卡| 久久久久影院美女国产主播| 国产色综合天天综合网| 日韩人妻无码精品久久久不卡| 亚洲国产另类久久久精品黑人| 国产精品午夜爆乳美女视频| 亚洲精品久久久www小说| 邻居少妇张开双腿让我爽一夜| 久久久久蜜桃精品成人片| 精品成人毛片一区二区| 少妇的肉体aa片免费| 久久婷婷激情综合色综合俺也去 | 国产精品国产av片国产| 国产精品门事件av| 日本一本二本三区免费| av成人无码无在线观看| 2021久久超碰国产精品最新| 国产乡下三级全黄三级|