在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Adenosine kinase (ADK)

Recombinant Human Adenosine kinase (ADK)

  • 中文名稱：
    Recombinant Human Adenosine kinase(ADK)
  • 貨號：
    CSB-YP346232HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Adenosine kinase(ADK)
  • 貨號：
    CSB-EP346232HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Adenosine kinase(ADK)
  • 貨號：
    CSB-EP346232HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Adenosine kinase(ADK)
  • 貨號：
    CSB-BP346232HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Adenosine kinase(ADK)
  • 貨號：
    CSB-MP346232HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ADK
  • Uniprot No.：
  • 別名：
    2310026J05Rik; 5033405D03Rik; Adenosine 5''-phosphotransferase; Adenosine kinase; adk; ADK_HUMAN; AI255373; AI987814; AK; MGC6593; OTTHUMP00000019864; OTTHUMP00000019865
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-362
  • 氨基酸序列
    AAAEEEPKP KKLKVEAPQA LRENILFGMG NPLLDISAVV DKDFLDKYSL KPNDQILAED KHKELFDELV KKFKVEYHAG GSTQNSIKVA QWMIQQPHKA ATFFGCIGID KFGEILKRKA AEAHVDAHYY EQNEQPTGTC AACITGDNRS LIANLAAANC YKKEKHLDLE KNWMLVEKAR VCYIAGFFLT VSPESVLKVA HHASENNRIF TLNLSAPFIS QFYKESLMKV MPYVDILFGN ETEAATFARE QGFETKDIKE IAKKTQALPK MNSKRQRIVI FTQGRDDTIM ATESEVTAFA VLDQDQKEII DTNGAGDAFV GGFLSQLVSD KPLTECIRAG HYAASIIIRR TGCTFPEKPD FH
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
  • 基因功能參考文獻：
    1. The results of this study showed that over-expression of the major adenosine removing enzyme ADK in reactive astrocytes and subpopulation of remaining neurons in Rasmussen Encephalitis patients plays an important role in the epileptogensis of Rasmussen Encephalitis. PMID: 28789481
    2. rs11001109 rare allele homozygosity is associated with increased risk of post-traumatic epilepsy development after brain injury. PMID: 26040919
    3. The results of this study suggest that upregulation of ADK is a common pathologic component of FCDIIB. PMID: 25575137
    4. These results suggest that upregulation of ADK is a common pathologic hallmark of Rasmussen encephalitis and that ADK might be a target in the treatment of epilepsy associated with Rasmussen encephalitis. PMID: 24128682
    5. Data show that we a significantly higher expression of ADK in the peritumoral infiltrated tissue of patients with epilepsy than in patients without epilepsy. PMID: 22092111
    6. The results of this study suggested that dysregulation of ADK in astrocytes is a common pathologic hallmark of temporal lobe epilepsy. PMID: 21635241
    7. The cytoplasmic isoform of adenosine kinase is sufficient to alter sleep physiology. ADK might orchestrate neurotransmitter pathways involved in the generation of electroencephlogram oscillations and regulation of sleep. PMID: 20881134
    8. The catalytic properties, gene expression and protein levels of certain proteins involved in mitochondrial ATP synthesis, such as F1F0-ATPase, ANT and AK, in human skin fibroblasts with trisomic karyotype, compared them with euploid fibroblasts. PMID: 20698827
    9. Equilibrative nucleoside transporters (hENT1, hENT2) together with adenosine kinase and 5'-nucleotidase play a crucial role in the regulation of CFTR through an adenosine-dependent pathway in human airway epithelia. PMID: 12820662
    10. role for HIF-1alpha in transcriptional repression of AK in hypoxia PMID: 18309031
    11. adenosine kinase gene expression was significantly higher in cancer than in normal-appearing tissue, in line with our previous measurements of adenosine kinase enzyme activities in colorectal tumor samples PMID: 18600536
    12. both deoxycytidine kinase and adenosine kinase are involved in this model of ADA deficiency PMID: 18600545
    13. This study reports for the first time subcellular localization of the enzyme AdK in mammalian cells. PMID: 19635462

    顯示更多

    收起更多

  • 相關疾病：
    Hypermethioninemia due to adenosine kinase deficiency (HMAKD)
  • 亞細胞定位：
    [Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm.
  • 蛋白家族：
    Carbohydrate kinase PfkB family
  • 組織特異性：
    Widely expressed. Highest level in placenta, liver, muscle and kidney.
  • 數據庫鏈接：

    HGNC: 257

    OMIM: 102750

    KEGG: hsa:132

    STRING: 9606.ENSP00000286621

    UniGene: Hs.656586



主站蜘蛛池模板： 亚洲欧美日韩成人综合网 | 免费看成人午夜福利专区| 国产传媒麻豆剧精品av| 一区二区三区国产精华液| 717影院理论午夜伦八戒| 狠狠色噜噜狠狠狠888米奇| 精品蜜臀久久久久99网站| 暖暖视频日本在线观看| 亚洲 激情 小说 另类 欧美| 久久天天躁夜夜躁狠狠综合| 少妇大胆瓣开下部自慰| 成人试看120秒体验区| 少妇太爽了在线观看免费视频| 人人爽人人澡人人高潮| 无码动漫性爽xo视频在线观看 | 人与嘼交av免费| 亚洲处破女av日韩精品| 成人免费毛片内射美女app| 国产成人无码av一区二区| 色偷偷av亚洲男人的天堂| 国产精品亚洲专区无码web| 国产亚洲精品久久综合阿香| 亚洲乱码在线卡一卡二卡新区| 色婷婷综合中文久久一本| 国产产区一二三产区区别在线| 成人国产片视频在线观看| 天堂资源在线www在线观看| 午夜理论片yy6080私人影院| а√天堂资源官网在线资源| 日韩经典精品无码一区| 国产精品 精品国内自产拍| 男女性爽大片视频| 色婷婷国产精品高潮呻吟av久久| 国产农村毛卡片| av中文无码韩国亚洲色偷偷 | 久久久亚洲精华液精华液精华液 | 阳茎伸入女人阳道视频免费| 亚洲人成网站在线无码| 国产乱人伦偷精精品视频| 人妻激情另类乱人伦人妻| 狠狠躁夜夜躁人人爽天天 |