在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Activating signal cointegrator 1 complex subunit 3 (ASCC3)

  • 中文名稱:
    Recombinant Human Activating signal cointegrator 1 complex subunit 3(ASCC3)
  • 貨號:
    CSB-EP002198HU
  • 規格:
    ¥1536
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    ASCC3
  • Uniprot No.:
  • 別名:
    Activating signal cointegrator 1 complex subunit 3; ASC-1 complex subunit p200; ASC-1 complex subunit p200-KD subunit; ASC1p200; ascc3; ATP binding 1; B630009I04Rik; dJ121G13.4; DJ467N11.1; HELC1_HUMAN; HELIC1; Helicase; helicase; ATP binding 1; p200; RNA helicase family; RNAH; RP1-121G13.4; Trip4 complex subunit p200
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Isoform 2
  • 來源:
    E.coli
  • 分子量:
    40.0kDa
  • 表達區域:
    1-111aa
  • 氨基酸序列
    MALPRLTGALRSFSNVTKQDNYNEEVADLKIKRSKLHEQVLDLGLTWKKIIKFLNEKLEKSKMQSINEDLKDILHAAKQIEVNCPFQKRRLDGKEEDEKMSRASDRFRGLR
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Also involved in activation of the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation. Drives the splitting of stalled ribosomes, as part of the ribosome quality control trigger (RQT) complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation.
  • 基因功能參考文獻:
    1. UV exposure results in spatial restriction of transcription and slower elongation, with the result that only the promoter-proximal 20-25 kb are efficiently transcribed; these events underlie a switch to expression of short mRNA isoforms and preferential use of alternative last exons in a number of genes, including ASCC3. PMID: 28215706
    2. ASCC3 Gene Polymorphism was associated with Chronic Hepatitis B. PMID: 26536629
    3. Silencing of ASCC3 resulted in upregulation of multiple antiviral interferon-stimulated genes, which correlated with inhibition of infection of several positive-strand RNA viruses. PMID: 23781071
    4. DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation. PMID: 22055184
  • 亞細胞定位:
    Nucleus. Nucleus speckle. Cytoplasm, cytosol.
  • 蛋白家族:
    Helicase family
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 18697

    OMIM: 614217

    KEGG: hsa:10973

    STRING: 9606.ENSP00000358159

    UniGene: Hs.486031



主站蜘蛛池模板: 久久久噜噜噜久久熟女| 色夜码无码av网站| 九九视频免费精品视频| 中文字幕无码第1页| 亚洲的天堂av无码| 久久久噜噜噜久久熟女aa片| 久久无码精品一一区二区三区| 国产精品成人一区二区三区| 午夜免费啪视频| 亚洲午夜成人久久久久久| 又色又爽又黄的视频女女| 粗大的内捧猛烈进出视频| 粗大猛烈进出高潮视频免费看| 亚洲欧美中文日韩在线视频一 | 婷婷综合另类小说色区| 男女野外做爰全过程69影院| 国产av亚洲精品ai换脸电影| 欧美人妻少妇精品久久黑人 | 日韩精品成人无码专区免费| 亚洲日韩精品一区二区三区无码 | 亚洲а∨天堂久久精品| 亚洲熟女综合色一区二区三区| 久久亚洲春色中文字幕久久久| 亚洲国产最大av| 麻豆视传媒官网免费观看| 亚洲乱码av中文一区二区| 自拍日韩亚洲一区在线| 国产成人精品永久免费视频| 久久精品一本到东京热| 亚洲aⅴ无码成人网站国产app| 亚洲国产精品无码一线岛国| 亚洲精品久久久无码av片软件 | 饥渴少妇做私密保健视频| 一区二区三区四区在线不卡高清| 色欲香天天天综合网站| 久久久精品人妻一区二区三区蜜桃| 丰满少妇做爰视频爽爽和| 无码专区久久综合久中文字幕| 日本丰满白嫩大屁股ass| 琪琪秋霞午夜av影视在线| 好爽好舒服要高潮了视频|