在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human AT-hook-containing transcription factor (AKNA), partial

  • 中文名稱:
    Recombinant Human AT-hook-containing transcription factor(AKNA) ,partial
  • 貨號:
    CSB-YP767203HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human AT-hook-containing transcription factor(AKNA) ,partial
  • 貨號:
    CSB-EP767203HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human AT-hook-containing transcription factor(AKNA) ,partial
  • 貨號:
    CSB-EP767203HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human AT-hook-containing transcription factor(AKNA) ,partial
  • 貨號:
    CSB-BP767203HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human AT-hook-containing transcription factor(AKNA) ,partial
  • 貨號:
    CSB-MP767203HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    AKNA
  • Uniprot No.:
  • 別名:
    AKNA; KIAA1968; Microtubule organization protein AKNA; AT-hook-containing transcription factor
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Centrosomal protein that plays a key role in cell delamination by regulating microtubule organization. Required for the delamination and retention of neural stem cells from the subventricular zone during neurogenesis. Also regulates the epithelial-to-mesenchymal transition in other epithelial cells. Acts by increasing centrosomal microtubule nucleation and recruiting nucleation factors and minus-end stabilizers, thereby destabilizing microtubules at the adherens junctions and mediating constriction of the apical endfoot. In addition, may also act as a transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development. Binds to A/T-rich promoters. It is unclear how it can both act as a microtubule organizer and as a transcription factor; additional evidences are required to reconcile these two apparently contradictory functions.
  • 基因功能參考文獻:
    1. Authors suggest that regulatory and coding polymorphisms of the inflammatory modulator gene AKNA can influence the development of KOA. PMID: 29368274
    2. identified HIF1A Pro582Ser T allele and C/T genotype as well as AKNA -1372C>A polymorphism A/A genotype as genetic factors associated with Primary Sjogren's Syndrome. PMID: 28484714
    3. Results support the hypothesis that akna is a cervical cancer susceptibility genetic factor and suggest that akna transcriptional regulation has a role in the disease; identified an association between high akna expression levels and cervical cancer and squamous intraepithelial lesion, but its direction differs in each disease stage. PMID: 25373726
    4. significantly decreased expression of CD18 and AKNA suggests a role for both proteins in the pathogenesis of Vogt-Koyanagi-Harada syndrome PMID: 21297967
    5. Data indicate that AKNA appears to be an important genetic factor associated with the risk cervical cancer. PMID: 20507260
    6. AKNA expresses multiple transcripts and protein isoforms as a result of alternative promoter usage, splicing, and polyadenylation. PMID: 15869410

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus.
  • 組織特異性:
    Predominantly expressed by lymphoid tissues. Highly expressed in the spleen, lymph nodes and peripheral blood leukocytes, expressed at lower level in the thymus. Mainly expressed by germinal center B-lymphocytes, a stage in which receptor and ligand inter
  • 數據庫鏈接:

    HGNC: 24108

    OMIM: 605729

    KEGG: hsa:80709

    STRING: 9606.ENSP00000303769

    UniGene: Hs.494895



主站蜘蛛池模板: 无码人妻一区、二区、三区免费视频| 成人欧美一区二区三区在线| 日本在线看片免费人成视频| 亚洲不卡一卡2卡三卡4卡5卡| 亚洲综合伊人久久大杳蕉| 亚洲视频在线观看| 玩弄少妇人妻| 四虎一区二区成人免费影院网址| 午夜人妻理论片天堂影院| 国产亚洲精品久久久久丝瓜| 97人人模人人爽人人喊网| 日本又色又爽又黄的视频免| 九九久久精品国产免费看小说| 国产精品久久国产精品99 | 国产午夜a理论毛片| 国产精品人妻久久久久| 国产精品成人va在线观看| 无码国产欧美一区二区三区不卡 | 私人毛片免费高清影视院| 无码中文av有码中文a| 69风韵老熟女口爆吞精| 国内精品久久久久久久小说| 日本一二三区视频在线| 久久久久精品无码一区二区三区| 无码中文av波多野结衣一区| 国产精品99精品无码视亚| 大香伊蕉在人线国产网站首页| 久青青在线观看视频国产| 国产成人精品一区二三区| 久久国产劲暴∨内射新川| 国产1卡2卡3卡4卡免费| 国产日韩在线视看第一页| 精品熟人妻一区二区三区四区不卡| 麻豆丰满少妇chinese| aⅴ亚洲 日韩 色 图网站 播放| 精品无码三级在线观看视频| 狼人亚洲国内精品自在线| 美女露出粉嫩小奶头在视频18禁| 亚洲国产精品无码久久98| 久久亚洲精品国产精品777777| 国产成人av在线影院无毒|