在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human ADP-ribosylation factor-like protein 4C (ARL4C)

  • 中文名稱:
    Recombinant Human ADP-ribosylation factor-like protein 4C(ARL4C)
  • 貨號:
    CSB-YP002086HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human ADP-ribosylation factor-like protein 4C(ARL4C)
  • 貨號:
    CSB-EP002086HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human ADP-ribosylation factor-like protein 4C(ARL4C)
  • 貨號:
    CSB-EP002086HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human ADP-ribosylation factor-like protein 4C(ARL4C)
  • 貨號:
    CSB-BP002086HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human ADP-ribosylation factor-like protein 4C(ARL4C)
  • 貨號:
    CSB-MP002086HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ARL4C
  • Uniprot No.:
  • 別名:
    ADP ribosylation factor like 4C; ADP ribosylation factor like 7; ADP-ribosylation factor-like protein 4C; ADP-ribosylation factor-like protein 7; ADP-ribosylation factor-like protein LAK; Arl4c; ARL4C_HUMAN; ARL7; LAK
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-192
  • 氨基酸序列
    GNISSNISA FQSLHIVMLG LDSAGKTTVL YRLKFNEFVN TVPTIGFNTE KIKLSNGTAK GISCHFWDVG GQEKLRPLWK SYSRCTDGII YVVDSVDVDR LEEAKTELHK VTKFAENQGT PLLVIANKQD LPKSLPVAEI EKQLALHELI PATTYHVQPA CAIIGEGLTE GMDKLYEMIL KRRKSLKQKK KR
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process.
  • 基因功能參考文獻:
    1. We demonstrate that ARL4C knockdown likely attenuates osteogenesis of hASCs through inhibition of the Wnt signaling pathway. These results provide new insights into the mechanisms of osteogenic differentiation and provide a potential molecular target for bone tissue engineering. PMID: 29432742
    2. ARL4C is expressed due to hypomethylation in the 3'-UTR for certain types of cancers and that ARL4C methylation status is involved in squamous cell carcinoma cell function. PMID: 27835592
    3. Arl4c as a novel Wnt signal target molecule that links epithelial tubulogenesis to tumourigenesis. PMID: 28053143
    4. Results indicated that overexpression of Arl4c might contribute to the tumorigenesis and might play a pivotal role in the progression of CRC. PMID: 26756615
    5. Arl4c is involved in tumorigenesis and might represent a novel therapeutic target for suppressing proliferation and invasion of colorectal and lung cancer cells. PMID: 25486429
    6. Study shows that three related Arf-like GTPases Arl4a, Arl4c, and Arl4d, are able to recruit ARNO and other cytohesins to the plasma membrane by binding to their PH domains irrespective of whether they are in the diglycine or triglycine form. PMID: 17398095
    7. ARL7 might modulate the intracellular vesicular transport via interaction with microtubules. PMID: 19409876

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell projection, filopodium. Cell membrane. Cytoplasm.
  • 蛋白家族:
    Small GTPase superfamily, Arf family
  • 組織特異性:
    Expressed in several tumor cell lines (at protein level). Expressed in lung, brain, leukocytes and placenta.
  • 數據庫鏈接:

    HGNC: 698

    OMIM: 604787

    KEGG: hsa:10123

    STRING: 9606.ENSP00000375057

    UniGene: Hs.111554



主站蜘蛛池模板: 欧美性受xxxx狂喷水| 亚洲а∨天堂久久精品| 国产激情电影综合在线看| 在线成人一区二区| 青青国产线免观| 亚洲精品国产综合久久一线| 牲高潮99爽久久久久777| 亚洲精品久久久久久中文传媒| 男人扒女人添高潮视频| 国产一卡三卡四卡无卡精品| 亚洲桃色天堂网| 欧美男男大粗吊1069| 国产色婷婷五月精品综合在线| 18禁黄网站禁片无遮挡观看 | 97久久久人妻一区精品| 亚洲乱码av中文一区二区软件| 特黄三级又爽又粗又大| 亚洲欧美日韩成人高清在线一区| 一本色道无码道在线观看| 欧美成人免费全部观看| 少妇久久久久久被弄高潮| 亚洲欧美精品伊人久久| 一区二区精品视频日本| 亚洲男人的天堂在线aⅴ视频| 人人插人人插人人爽| 97久久久久人妻精品区一| 国内精品乱码卡一卡2卡| 无码播放一区二区三区| 国产思思99re99在线观看| 久草热8精品视频在线观看| 欧美 亚洲 日韩 中文2019| 狠狠躁夜夜躁av网站中文字幕| 人妻丝袜av中文系列先锋影音| 99精品国产在热久久无毒| 亚洲熟妇无码另类久久久| 亚洲国产成人久久一区二区三区 | 国产精品久久久久9999小说| 纯肉无遮挡无码日本动漫| 无码三级在线看中文字幕完整版| 中文字幕人妻中文av不卡专区 | 8ⅹ8x擦拨擦拨成人免费视频|