在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAMTS8)

Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAMTS8)

  • 中文名稱：
    Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 8(ADAMTS8)
  • 貨號：
    CSB-YP891979HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 8(ADAMTS8)
  • 貨號：
    CSB-EP891979HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 8(ADAMTS8)
  • 貨號：
    CSB-EP891979HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 8(ADAMTS8)
  • 貨號：
    CSB-BP891979HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 8(ADAMTS8)
  • 貨號：
    CSB-MP891979HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ADAMTS8
  • Uniprot No.：
  • 別名：
    ADAMTS8; METH2; A disintegrin and metalloproteinase with thrombospondin motifs 8; ADAM-TS 8; ADAM-TS8; ADAMTS-8; EC 3.4.24.-; METH-2; METH-8
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    214-889
  • 氨基酸序列
    FVSEARF VETLLVADAS MAAFYGADLQ NHILTLMSVA ARIYKHPSIK NSINLMVVKV LIVEDEKWGP EVSDNGGLTL RNFCNWQRRF NQPSDRHPEH YDTAILLTRQ NFCGQEGLCD TLGVADIGTI CDPNKSCSVI EDEGLQAAHT LAHELGHVLS MPHDDSKPCT RLFGPMGKHH VMAPLFVHLN QTLPWSPCSA MYLTELLDGG HGDCLLDAPA AALPLPTGLP GRMALYQLDQ QCRQIFGPDF RHCPNTSAQD VCAQLWCHTD GAEPLCHTKN GSLPWADGTP CGPGHLCSEG SCLPEEEVER PKPVADGGWA PWGPWGECSR TCGGGVQFSH RECKDPEPQN GGRYCLGRRA KYQSCHTEEC PPDGKSFREQ QCEKYNAYNY TDMDGNLLQW VPKYAGVSPR DRCKLFCRAR GRSEFKVFEA KVIDGTLCGP ETLAICVRGQ CVKAGCDHVV DSPRKLDKCG VCGGKGNSCR KVSGSLTPTN YGYNDIVTIP AGATNIDVKQ RSHPGVQNDG NYLALKTADG QYLLNGNLAI SAIEQDILVK GTILKYSGSI ATLERLQSFR PLPEPLTVQL LTVPGEVFPP KVKYTFFVPN DVDFSMQSSK ERATTNIIQP LLHAQWVLGD WSECSSTCGA GWQRRTVECR DPSGQASATC NKALKPEDAK PCESQLCPL
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Has anti-angiogenic properties.
  • 基因功能參考文獻：
    1. This study showed that ADAMTS1, 8, and 18 are highly expressed in GC and its nodal metastases, suggesting important roles of these proteases in carcinogenesis and lymphatic metastasis. The findings from the present study indicate that these proteases may be promising candidates for novel and alternative treatments in GC (gastric cancer) PMID: 28814085
    2. ADAMTS8 hypermethylation is associated with decreased expression in gastric cancer. PMID: 27493958
    3. Study uncovers the tumor suppressive function of ADAMTS8 and its frequent methylation in certain tumors could be developed as a potential biomarker. PMID: 24184540
    4. Ability of ADAMTS-8 to cleave aggrecan at aggrecanase-susceptible Glu373-Ala374 peptide bond. Presence of ADAMTS-8 mRNA transcripts in normal and osteoarthritic human cartilage. (ADAMTS-8) PMID: 15296936
    5. Downdownregulation of METH-2 expression in primary NSCLC, often associated with promoter hypermethylation, is a frequent event, which may be related to the development of the disease. PMID: 15328519
    6. ADAMTS8 and ADAMTS15 have emerged as novel predictors of survival in patients with breast carcinoma PMID: 16152618
    7. Immunohistochemistry and Western analysis indicated downregulation of ADAMTS-8 protein in >77% brain tumours. A role for ADAMTS-8 in brain tumorigenesis, warranting further investigation into its role in regulation of tumour angiogenesis. PMID: 16570050
    8. ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of atherosclerotic plaques PMID: 17606262

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 組織特異性：
    Highly expressed in adult and fetal lung, lower expression in brain, placenta, heart, stomach and fetal brain and kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 224

    OMIM: 605175

    KEGG: hsa:11095

    STRING: 9606.ENSP00000257359

    UniGene: Hs.271605



主站蜘蛛池模板： 欧美亚洲精品一区二区| 国产成人亚洲综合色婷婷秒播 | 狠狠躁夜夜躁av网站中文字幕| 久久亚洲私人国产精品va| 亚洲一卡2卡3卡4卡国产| 免费国产污网站在线观看| 国产欧美亚洲日韩图片| 国产精品成人99一区无码 | 国产区图片区小说区亚洲区| 亚洲中文字幕日产乱码在线| 他掀开裙子把舌头伸进去添视频| 高清不卡一区二区三区| 亚洲午夜福利av一区二区无码| 亚洲国产精品一区二区久久| 久久人妻xunleige无码| 亚洲大码熟女在线| 亚洲精品色午夜无码专区日韩| 吃奶呻吟打开双腿做受在线视频| 曰本大码熟中文字幕| 啪一啪射一射插一插| 女性高爱潮视频| 四虎成人精品无码永久在线 | 野外做受又硬又粗又大视幕| 全免费又大粗又黄又爽少妇片| 久久亚洲精品国产亚洲老地址| 国产成人亚洲精品无码车a| 国产精品久久久久久人妻精品| 亚洲日韩中文无码久久| 精品成人免费国产片| 久久精品一本到东京热| 欧美特级特黄aaaaaa在线看| 欧美丰满少妇xxxx性| 久久久久久成人综合网| 久久丫精品系列| 99这里只有精品| 激情久久亚洲小说| 色欲综合久久躁天天躁| 日日碰狠狠躁久久躁蜜桃| 亚洲色大网站www永久网站| 国产免费高清69式视频在线观看| 久久久久成人精品免费播放动漫|