在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human RNA-binding protein RO60 (RO60)

Recombinant Human RNA-binding protein RO60 (RO60)

  • 中文名稱：
    人TROVE2重組蛋白
  • 貨號：
    CSB-YP025071HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人TROVE2重組蛋白
  • 貨號：
    CSB-EP025071HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人TROVE2重組蛋白
  • 貨號：
    CSB-EP025071HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人TROVE2重組蛋白
  • 貨號：
    CSB-BP025071HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人TROVE2重組蛋白
  • 貨號：
    CSB-MP025071HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    TROVE2
  • Uniprot No.：
  • 別名：
    60 kDa ribonucleoprotein Ro; 60 kDa Ro protein; 60 kDa SS A/Ro ribonucleoprotein; 60 kDa SS-A/Ro ribonucleoprotein; Autoantigen Ro/SSA, 60-KD; bA101E13.2; Gastric cancer multi drug resistance protein; Ribonucleoprotein autoantigen SS A/Ro; RO 60; Ro 60 kDa autoantigen; RO60; RO60_HUMAN; RoRNP; Sjoegren syndrome antigen A2; Sjoegren syndrome type A antigen; Sjogren syndrome antigen A2 (60kD ribonucleoprotein autoantigen SS A/Ro); Sjogren syndrome antigen A2 (60kDa ribonucleoprotein autoantigen SS A/Ro); Sjogren syndrome antigen A2; SS A; SS-A; SS-A/Ro; SSA 2; SSA; SSA2; TROVE 2; TROVE domain family member 2; TROVE2
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-538
  • 氨基酸序列
    MEESVNQMQP LNEKQIANSQ DGYVWQVTDM NRLHRFLCFG SEGGTYYIKE QKLGLENAEA LIRLIEDGRG CEVIQEIKSF SQEGRTTKQE PMLFALAICS QCSDISTKQA AFKAVSEVCR IPTHLFTFIQ FKKDLKESMK CGMWGRALRK AIADWYNEKG GMALALAVTK YKQRNGWSHK DLLRLSHLKP SSEGLAIVTK YITKGWKEVH ELYKEKALSV ETEKLLKYLE AVEKVKRTRD ELEVIHLIEE HRLVREHLLT NHLKSKEVWK ALLQEMPLTA LLRNLGKMTA NSVLEPGNSE VSLVCEKLCN EKLLKKARIH PFHILIALET YKTGHGLRGK LKWRPDEEIL KALDAAFYKT FKTVEPTGKR FLLAVDVSAS MNQRVLGSIL NASTVAAAMC MVVTRTEKDS YVVAFSDEMV PCPVTTDMTL QQVLMAMSQI PAGGTDCSLP MIWAQKTNTP ADVFIVFTDN ETFAGGVHPA IALREYRKKM DIPAKLIVCG MTSNGFTIAD PDDRGMLDMC GFDTGALDVI RNFTLDMI
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation. Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammaotry cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes.; May play roles in cilia formation and/or maintenance.
  • 基因功能參考文獻：
    1. TROVE2 is a novel target of miR-128 in astrocytoma tissues and the expression of TROVE2 is increased with the pathological stages increasing. PMID: 26307612
    2. Significant relationships were found between clinical and laboratory manifestations of autoimmune and rheumatic diseases with different patterns of antibodies to anti-Ro52, anti-Ro60 and anti-La. PMID: 26725021
    3. These findings establish a link among the lupus autoantigen Ro60, Alu retroelements, and type I interferon. PMID: 26382853
    4. Findings indicate a relentless turnover of short-lived clonotypic variants, masquerading as long-lived Ro60 humoral autoimmunity. PMID: 23644453
    5. The Y3 RNA moiety of the Ro60 ribonucleoprotein plays a critical role in the pathogenesis of fetal cardiac injury by altering the subcellular location of Ro60 autoantibodies. PMID: 23698747
    6. these data indicate that ZBP1 may function as an adapter to export the Ro/Y3 RNA complex from nuclei. PMID: 22114317
    7. conclude that RNPs containing hY RNAs and Ro60, La or nucleolin are not required for the function of hY RNAs in chromosomal DNA replication in a human cell-free system, which can be mediated by Y RNAs outside of these RNPs PMID: 21060685
    8. dichotomy of human autoantibody responses against mutually exclusive determinants linked to a single domain of a systemic autoantigen and supports a model in which tolerance is broken by different immunogenic forms of Ro 60 PMID: 20131295
    9. Activation of Toll-like receptors by fetal factor Ro60-associated single-stranded RNA particles is relevant in autoimmune-associated congenital heart block, where the obligate maternal factor is an anti-SSA/Ro autoantibody. PMID: 20089705
    10. In viitro RNA chaperone activity of SSA2 was studied. PMID: 15928345
    11. The structural organization and Zn2+-dependent subdomain interactions involving autoiantigenic epitopes in the RBBC region of SS-A were studied. PMID: 15964842
    12. interactions between Ro-Y5 and L5-5S RNPs establish 5S RNA as a target of quality control PMID: 18056422
    13. results demonstrate that Ro 60 functions as a novel receptor for beta(2)GPI on the surface of apoptotic cells. The formation of Ro 60-beta(2)GPI complexes may protect against anti-Ro 60 autoantibody-mediated tissue injury. PMID: 19248095

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • 蛋白家族：
    Ro 60 kDa family
  • 數據庫鏈接：

    HGNC: 11313

    OMIM: 600063

    KEGG: hsa:6738

    STRING: 9606.ENSP00000356411

    UniGene: Hs.288178



主站蜘蛛池模板： 骚动漫十八禁在线观看| 日本亚洲色大成网站www久久| 亚洲一区二区三区丝袜| 尤物av无码色av无码| 成在人线av无码免费看| 2020精品自拍视频曝光| 2019久久视频这里有精品15| 天天躁日日躁狠狠躁人妻| 人妻熟妇乱又伦精品视频无广告| 亚洲一区二区| 自拍性旺盛老熟女| 噜噜噜亚洲色成人网站| 国产精品久久久久久成人影院| 越猛烈欧美xx00动态图| 丝袜高潮流白浆潮喷在线播放 | 国产日产久久高清欧美一区| 亚洲伊人久久精品影院| 日韩欧美在线综合网| av香港经典三级级 在线| 国产一二三四区乱码免费| 国产99视频精品免费观看9| 国产午夜精品无码一区二区| 92电影网午夜福利| 亚洲精品天天影视综合网| 精品国产乱码久久久久久乱码| 欧美自拍亚洲综合图区| 中文国产成人精品久久不卡| 亚洲偷自拍国综合| 国内偷窥一区二区三区视频| 亚洲成在人线在线播放无码| 国产午夜福利在线观看红一片 | 国产沙发午睡系列999| 精品无码成人久久久久久| 欧美性猛交aaaa片黑人| 男人添女人下部高潮视频| 香港特级三a毛片免费观看| 清纯小美女主播流白浆| 丰满少妇被猛烈进入无码| 国产精品制服| 女人夜夜春高潮爽a∨片| 成人免费ā片在线观看|