在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8), partial

Recombinant Human 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8), partial

  • 中文名稱：
    人UGT8重組蛋白
  • 貨號：
    CSB-YP618101HU1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人UGT8重組蛋白
  • 貨號：
    CSB-EP618101HU1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人UGT8重組蛋白
  • 貨號：
    CSB-EP618101HU1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人UGT8重組蛋白
  • 貨號：
    CSB-BP618101HU1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人UGT8重組蛋白
  • 貨號：
    CSB-MP618101HU1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    UGT8
  • Uniprot No.：
  • 別名：
    UGT8; CGT; UGT4; 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; Ceramide UDP-galactosyltransferase; Cerebroside synthase; UDP-galactose-ceramide galactosyltransferase
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Galactosylates both hydroxy- and non-hydroxy fatty acid-containing ceramides and diglycerides.
  • 基因功能參考文獻：
    1. An increase in the immunolabelling of ceramide was observed in cells where UDP glycosyltransferase 8 (UGT8) was down-regulated as opposed to cells where UGT8 was either not regulated or was up-regulated. PMID: 28746357
    2. Data indicate that ceramide galactosyltransferase (UGT8), although enhanced in non-small cell lung carcinoma (NSCLC) tissues, does not meet the criteria of a lung tumor marker. PMID: 27620310
    3. Our study suggests that CGT expression is controlled by balanced expression of the negative modulator OLIG2 and positive regulator Nkx2.2, providing new insights into how expression of GalCer is tightly regulated in cell-type- and stage-specific manners. PMID: 24821492
    4. A new role was identified for UGT8 as a modulator of bile acid homeostasis. PMID: 25519837
    5. High expression of UGT8 accompanied by accumulation of GalCer in MDA-MB-231 cells is associated with a much higher proliferative index and a lower number of apoptotic cells in comparison to the MDA/LUC-shUGT8 cells. PMID: 24391908
    6. Comprehensive genomic analyses associate UGT8 variants with musical ability in a Mongolian population. PMID: 23118445
    7. UGT8 is a significant index of tumour aggressiveness and is seen in lung metastases of breast cancer. PMID: 20648017
    8. Single-nucleotide polymorphisms (SNPs) were found in UGT8 gene PMID: 12376738
    9. the GC-box and CRE function cooperatively, and that the CRE regulates the cell-specific expression of the hCGT gene PMID: 15229398
    10. We postulate that molecular link between defective GALT enzyme, which result in classic galactosemia and the cerebroside galactosyl transferase, responsible for galactosylation of cerebrosides, is dependent on concentrations of UDP-galactose. PMID: 16125333
    11. Gene expression of galactosyl ceramide synthase associated with poor pathohistological grading in breast cancer PMID: 19125296

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Single-pass membrane protein. Endoplasmic reticulum.
  • 蛋白家族：
    UDP-glycosyltransferase family
  • 數據庫鏈接：

    HGNC: 12555

    OMIM: 601291

    KEGG: hsa:7368

    STRING: 9606.ENSP00000311648

    UniGene: Hs.144197



主站蜘蛛池模板： 欧美黑人又大又粗xxxxx| 中文字幕日本乱码仑区在线| 国产欧美日韩精品丝袜高跟鞋| 日韩欧美猛交xxxxx无码| 成全世界免费高清观看| 国产日产欧产精品精品app| 日韩亚洲国产主播在线不卡| 国模丽丽啪啪一区二区| 无遮挡又爽又刺激的视频 | 中文字幕无码人妻丝袜| 欧美乱码卡一卡二卡四卡免费| 日本中文字幕在线| 毛色毛片免费观看| 婷婷五月综合丁香在线| 免费观看又色又爽又湿的软件| 少妇人妻精品一区二区三区| 国产成人午夜福利在线观看| 欧美日韩人妻精品一区二区在线| 人人爽人人爽人人爽| 97人人模人人爽人人喊网| 婷婷丁香六月激情综合在线人| 亚洲精品无码不卡av| 欧洲美熟女乱又伦| 亚洲精品久久久久中文第一幕| 在线无码免费的毛片视频| 欧美做受又硬又粗又大视频| 无码中文字幕在线播放2| 亚洲自偷自偷在线成人网址| 色偷偷久久一区二区三区| 亚洲午夜成人片| 777米奇影视第四色| 美女扒开腿让男人桶爽揉| 国产精品一区二区av在线观看| 久久综合久久美利坚合众国| 久久精品香蕉绿巨人登场| 少妇无码av无码专区| av怡红院一区二区三区| 伊人无码精品久久一区二区| 性饥渴少妇av无码毛片| 亚洲欧美中文日韩在线v日本| 国色精品卡一卡2卡3卡4卡在线|