在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human 116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2), partial

  • 中文名稱:
    人EFTUD2重組蛋白
  • 貨號:
    CSB-YP617995HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人EFTUD2重組蛋白
  • 貨號:
    CSB-EP617995HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人EFTUD2重組蛋白
  • 貨號:
    CSB-EP617995HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人EFTUD2重組蛋白
  • 貨號:
    CSB-BP617995HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人EFTUD2重組蛋白
  • 貨號:
    CSB-MP617995HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    EFTUD2
  • Uniprot No.:
  • 別名:
    116 kDa; 116 kDa U5 small nuclear ribonucleoprotein component; EFTUD2; Elongation factor Tu GTP binding domain containing 2; Elongation factor Tu GTP-binding domain-containing protein 2; hSNU114; MFDGA; MFDM; SNRNP116; Snrp116; Snu114; SNU114 homolog; U5 116KD; U5 small nuclear ribonucleoprotein component; U5 snRNP specific protein, 116 kD; U5 snRNP specific protein, 116 kDa; U5 snRNP-specific protein; U5-116 kDa; U5-116KD; U5S1_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome.
  • 基因功能參考文獻:
    1. we report two individuals of Asian ancestry with Mandibulofacial dysostosis type Guion-Almeida (MFDGA), each harboring a novel, pathogenic splice site variant in EFTUD2 PMID: 29381487
    2. We report a clinical and extensive molecular study, including TCOF1, POLR1D, POLR1C, and EFTUD2 genes, in a series of 146 patients with TCS. PMID: 25790162
    3. An update on mandibulofacial dysostosis with microcephaly and EFTUD2 mutations has been presented. (Review) PMID: 26507355
    4. Novel heterozygous mutations in EFTUD2, detected by exome sequencing, in mandibulofacial dysostosis with Microcephaly syndrome. PMID: 25735261
    5. Results show that SNW1 directly associates with EFTUD2 and SNRNP200 and that disruption of SNW1 association with these proteins promotes the apoptosis of breast cancer cells. PMID: 25450007
    6. These data demonstrate that EFTUD2 restricts Hepatitis C Virus infection mainly through an RIG-I/MDA5-mediated, JAK-STAT-independent pathway, thereby revealing the participation of EFTUD2 as a novel innate immune regulator. PMID: 25878102
    7. A de nove deletion mutation at 17q21.31, encompassing the EFTUD2 gene, is associated with congenital mandibulofacial dysostosis with microcephaly. PMID: 24266672
    8. Three different mutations in EFTUD2 gene were found in patients with mandibulofacial dysostosis type Guion-Almeida syndrome PMID: 25387991
    9. Study describes loss-of-function mutations in EFTUD2 gene in patients with different clinical manifestations of Mandibulofacial dysostosis, Guion-Almeida type syndrome. PMID: 24470203
    10. the phenotype in patients with EFTUD2 mutations is much broader than previously anticipated; in addition to AFD type Guion-Almeida and syndromic esophageal atresia, oto-facial syndrome also belongs to the EFTUD2 mutation spectrum PMID: 23879989
    11. Novel mutations in EFTUD2 were discovered in 3 patients. These mutations expand the clinical features in patients with EFTUD2 mutations and demonstrate an overlap with oculo-auriculo-vertebral spectrum. PMID: 23239648
    12. EFTUD2 haploinsufficiency leads to syndromic oesophageal atresia. PMID: 23188108
    13. Validation studies of eight additional individuals with MFDM demonstrated causative EFTUD2 mutations in all affected individuals tested. PMID: 22305528

    顯示更多

    收起更多

  • 相關疾病:
    Mandibulofacial dysostosis with microcephaly (MFDM)
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, EF-G/EF-2 subfamily
  • 數(shù)據(jù)庫鏈接:

    HGNC: 30858

    OMIM: 603892

    KEGG: hsa:9343

    STRING: 9606.ENSP00000392094

    UniGene: Hs.151787



主站蜘蛛池模板: 亚洲成a∧人片在线观看无码| 一本一道波多野结衣av一区| 国产成人免费ā片在线观看| 日本最新免费二区| 老司机久久99久久精品播放免费| 伊人久久大香线蕉av仙人| 国产精品久久久爽爽爽麻豆色哟哟 | 欧美激情性做爰免费视频| 日韩精品无码一本二本三本色| 国产欧美另类久久久精品丝瓜| 久久人人做人人妻人人玩精品va| 国产免费无遮挡吸乳视频| 亚洲日韩欧美一区二区三区在线| 中文字幕一区二区精品区| 在线日韩av免费永久观看| 香港aa三级久久三级| 亚洲综合一区无码精品| 尤物193在线人妻精品免费| 久久狼人大香伊蕉国产| 一区二区三区无码高清视频| 亚洲色成人www永久网站| 欧美片内射欧美美美妇| 国产成av人片在线观看无码| 国产精品国产高清国产av | 国产在线无码一区二区三区视频| 人妻熟女一二三区夜夜爱| 午夜无码性爽快影院6080| 热99re久久精品这里都是精品免费| 亚洲国产成人久久综合一区| 丁香五月亚洲综合深深爱| 国产未成女一区二区| 天美麻花果冻视频大全英文版| 国产猛男猛女超爽免费视频| 东京热无码一区二区三区av| 日本污ww视频网站| 十八禁视频网站在线观看| 7777精品伊久久久大香线蕉| 2021久久国自产拍精品| 国产亚洲一区二区在线观看| 色综合欧美亚洲国产| 国产交换配偶在线视频|