在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (PLCD4)

  • 中文名稱:
    人PLCD4重組蛋白
  • 貨號:
    CSB-YP866264HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PLCD4重組蛋白
  • 貨號:
    CSB-EP866264HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PLCD4重組蛋白
  • 貨號:
    CSB-BP866264HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PLCD4重組蛋白
  • 貨號:
    CSB-MP866264HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase delta 4; 1-phosphatidylinositol 4; 1-phosphatidylinositol-4; 5-bisphosphate phosphodiesterase delta-4; hPLCD4; MGC12837; Phosphoinositide phospholipase C delta 4; Phosphoinositide phospholipase C-delta-4; Phospholipase C delta 4; Phospholipase C-delta-4; PLC delta 4; PLC delta4; PLC-delta-4; PLCD4; PLCD4_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-762
  • 氨基酸序列
    MASLLQDQLT TDQDLLLMQE GMPMRKVRSK SWKKLRYFRL QNDGMTVWHA RQARGSAKPS FSISDVETIR NGHDSELLRS LAEELPLEQG FTIVFHGRRS NLDLMANSVE EAQIWMRGLQ LLVDLVTSMD HQERLDQWLS DWFQRGDKNQ DGKMSFQEVQ RLLHLMNVEM DQEYAFSLFQ AADTSQSGTL EGEEFVQFYK ALTKRAEVQE LFESFSADGQ KLTLLEFLDF LQEEQKERDC TSELALELID RYEPSDSGKL RHVLSMDGFL SYLCSKDGDI FNPACLPIYQ DMTQPLNHYF ICSSHNTYLV GDQLCGQSSV EGYIRALKRG CRCVEVDVWD GPSGEPVVYH GHTLTSRILF KDVVATVAQY AFQTSDYPVI LSLETHCSWE QQQTMARHLT EILGEQLLST TLDGVLPTQL PSPEELRRKI LVKGKKLTLE EDLEYEEEEA EPELEESELA LESQFETEPE PQEQNLQNKD KKKKSKPILC PALSSLVIYL KSVSFRSFTH SKEHYHFYEI SSFSETKAKR LIKEAGNEFV QHNTWQLSRV YPSGLRTDSS NYNPQELWNA GCQMVAMNMQ TAGLEMDICD GHFRQNGGCG YVLKPDFLRD IQSSFHPEKP ISPFKAQTLL IQVISGQQLP KVDKTKEGSI VDPLVKVQIF GVRLDTARQE TNYVENNGFN PYWGQTLCFR VLVPELAMLR FVVMDYDWKS RNDFIGQYTL PWTCMQQGYR HIHLLSKDGI SLRPASIFVY ICIQEGLEGD ES
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.; Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3.
  • 基因功能參考文獻(xiàn):
    1. Here, the authors report that the zebrafish/human phosphatidylinositol transfer protein Sec14l3/SEC14L2 act as GTPase proteins to transduce Wnt signals from Frizzled to phospholipase C (PLC). PMID: 28463110
    2. PLCdelta(1) and PLCdelta(4) are probably differentially regulated in distinct cellular compartments by PI(4,5)P(2) and the PH domain of PLCdelta(4) does not act as a localization signal PMID: 15037625
    3. Serial deletion analysis identified the core PLC-delta4 promoter region as being between -402 and -67, in which an E-box and an AP-1 binding site played important roles in the promoter activity. PMID: 17394098
  • 亞細(xì)胞定位:
    Membrane; Peripheral membrane protein. Nucleus. Cytoplasm. Endoplasmic reticulum. Note=Localizes primarily to intracellular membranes mostly to the endoplasmic reticulum.
  • 組織特異性:
    Highly expressed in skeletal muscle and kidney tissues, and at moderate level in intestinal tissue. Expressed in corneal epithelial cells.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 9062

    OMIM: 605939

    KEGG: hsa:84812

    STRING: 9606.ENSP00000388631

    UniGene: Hs.632528



主站蜘蛛池模板: 俄罗斯老熟妇色xxxx| 精品国产不卡一区二区三区| 国产亚洲成av人片在线观看| 午夜在线看的免费网站 | 精品欧美小视频在线观看| av鲁丝一区鲁丝二区鲁丝三区| 男女做爰猛烈叫床视频免费| 尤物av无码色av无码| 亚洲国产综合av在线观看| 免费无码av片在线观看网址| 亚洲精品揄拍自拍首页一| 女人与拘做受全过程免费视频| 男女啪啪做爰高潮无遮挡| 少妇精品偷拍高潮少妇小说| 国产亚洲综合欧美一区二区| 日本丰满少妇裸体自慰| 少妇的肉体k8经典| 成年免费视频播放网站推荐| 国产产在线精品亚洲aavv| 高潮喷水的毛片| 亚洲一线二线三线写真| 久久免费视频精品在线| 女人被爽到高潮视频免费国产| 黄页网址大全免费观看| 日本亲近相奷中文字幕| 免费人成网视频在线观看| 天堂а√在线地址8| 高潮毛片无遮挡高清免费| 欧美成人看片一区二区| 国产超碰人人做人人爽av| 国产午夜高潮熟女精品av软件| 香蕉久久福利院| 国产又色又爽又黄好看的视频| 亚洲精品无码不卡在线播放he| 永久不封国产av毛片| 国产成人艳妇aa视频在线| 亚洲成aⅴ人片久青草影院| 1313午夜精品理论片| 一个添下面两个吃奶把腿扒开 | 中文字幕人乱码中文| 伊人情人综合网|